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Polygenic risk and hostile environments: Links to stable and dynamic antisocial behaviors across adolescence

Author(s): E L Acland

Adverse environments are linked to elevated youth antisocial behavior. However, this relation is thought to depend, in part, on genetic susceptibility. The present study investigated whether polygenic risk for antisociality moderates relations between hosti...

Article GUID: 38329116
Title:Polygenic risk and hostile environments: Links to stable and dynamic antisocial behaviors across adolescence
Authors:E L Acland
Link:https://pubmed.ncbi.nlm.nih.gov/38329116/
DOI:10.1017/S095457942400004X
Category:
PMID:38329116
Dept Affiliation: PSYCHOLOGY
1 School of Psychoeducation, University of Montreal, Montreal, QC, Canada.
2 Research Centre, Sainte-Justine University Hospital, Montreal, QC, Canada.
3 Department of Educational and Counselling Psychology, McGill University, Montreal, QC, Canada.
4 School of Psychology, University of Queensland, Brisbane, Australia.
5 Department of Psychology, The Pennsylvania State University, University Park, PA, USA.
6 Ecole de Psychologie, Université Laval, Quebec, QC, Canada.
7 School of Criminology, Université de Montréal & Research Center of the Montreal Mental Health University Institute, Montreal, QC, Canada.
8 Department of Neurology, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munchen, Germany.
9 Department of Psychology, Concordia University, Montreal, QC, Canada.
10 School of Public Health, University of Montreal, Montreal, QC, Canada.
11 Départements de Pédiatrie et de Psychologie, Université de Montreal, Montreal, QC, Canada.

Description:

Adverse environments are linked to elevated youth antisocial behavior. However, this relation is thought to depend, in part, on genetic susceptibility. The present study investigated whether polygenic risk for antisociality moderates relations between hostile environments and stable as well as dynamic antisocial behaviors across adolescence. We derived two antisocial-linked polygenic risk scores (PRS) (N = 721) based on previous genome-wide association studies. Forms of antisocial behavior...