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Glucose-mediated repression of plant biomass utilization in the white-rot fungus Dichomitus squalens.

Author(s): Daly P, Peng M, Di Falco M, Lipzen A, Wang M, Ng V, Grigoriev IV, Tsang A, Mäkelä MR, de Vries RP

Appl Environ Microbiol. 2019 Oct 04;: Authors: Daly P, Peng M, Di Falco M, Lipzen A, Wang M, Ng V, Grigoriev IV, Tsang A, Mäkelä MR, de Vries RP

Article GUID: 31585998
Genetics of mating in members of the Chaetomiaceae as revealed by experimental and genomic characterization of reproduction in Myceliophthora heterothallica.

Author(s): Hutchinson MI, Powell AJ, Tsang A, O'Toole N, Berka RM, Barry K, Grigoriev IV, Natvig DO

Fungal Genet Biol. 2016 Jan;86:9-19 Authors: Hutchinson MI, Powell AJ, Tsang A, O'Toole N, Berka RM, Barry K, Grigoriev IV, Natvig DO

Article GUID: 26608618
Introduction: Overview of Fungal Genomics.

Author(s): de Vries RP, Grigoriev IV, Tsang A

Methods Mol Biol. 2018;1775:1-7 Authors: de Vries RP, Grigoriev IV, Tsang A

Article GUID: 29876804
Investigation of inter- and intraspecies variation through genome sequencing of Aspergillus section Nigri.

Author(s): Vesth TC, Nybo JL, Theobald S, Frisvad JC, Larsen TO, Nielsen KF, Hoof JB, Brandl J, Salamov A, Riley R, Gladden JM, Phatale P, Nielsen MT, ...

Nat Genet. 2018 12;50(12):1688-1695 Authors: Vesth TC, Nybo JL, Theobald S, Frisvad JC, Larsen TO, Nielsen KF, Hoof JB, Brandl J, Salamov A, Riley R, Gladden JM, Phatale P, Nielsen MT, Lyhne EK, K...

Article GUID: 30349117
The obligate alkalophilic soda-lake fungus Sodiomyces alkalinus has shifted to a protein diet.

Author(s): Grum-Grzhimaylo AA, Falkoski DL, van den Heuvel J, Valero-Jiménez CA, Min B, Choi IG, Lipzen A, Daum CG, Aanen DK, Tsang A, Henrissat B, Bil...

Mol Ecol. 2018 12;27(23):4808-4819 Authors: Grum-Grzhimaylo AA, Falkoski DL, van den Heuvel J, Valero-Jiménez CA, Min B, Choi IG, Lipzen A, Daum CG, Aanen DK, Tsang A, Henrissat B, Bilanenko ...

Article GUID: 30368956
The gold-standard genome of Aspergillus niger NRRL 3 enables a detailed view of the diversity of sugar catabolism in fungi.

Author(s): Aguilar-Pontes MV, Brandl J, McDonnell E, Strasser K, Nguyen TTM, Riley R, Mondo S, Salamov A, Nybo JL, Vesth TC, Grigoriev IV, Andersen MR,...

Stud Mycol. 2018 Sep;91:61-78 Authors: Aguilar-Pontes MV, Brandl J, McDonnell E, Strasser K, Nguyen TTM, Riley R, Mondo S, Salamov A, Nybo JL, Vesth TC, Grigoriev IV, Andersen MR, Tsang A, de Vrie...

Article GUID: 30425417
Title:The obligate alkalophilic soda-lake fungus Sodiomyces alkalinus has shifted to a protein diet.
Authors:Grum-Grzhimaylo AA,  Falkoski DL,  van den Heuvel J,  Valero-Jiménez CA,  Min B,  Choi IG,  Lipzen A,  Daum CG,  Aanen DK,  Tsang A,  Henrissat B,  Bilanenko EN,  de Vries RP,  van Kan JAL,  Grigoriev IV,  Debets AJM
Link:https://www.ncbi.nlm.nih.gov/pubmed/30368956?dopt=Abstract
DOI:10.1111/mec.14912
Category:Mol Ecol
PMID:30368956
Dept Affiliation: GENOMICS
1 Laboratory of Genetics, Wageningen University, Wageningen, The Netherlands.
2 Fungal Physiology, Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands.
3 R&D Department, Novozymes Latin America, Araucária, Paraná, Brazil.
4 Laboratory of Phytopathology, Wageningen University, Wageningen, The Netherlands.
5 US Department of Energy Joint Genome Institute, Walnut Creek, California.
6 Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Korea.
7 Centre for Structural and Functional Genomics, Concordia University, Montreal, Quebec, Canada.
8 Architecture et Fonction des Macromolécules Biologiques, Aix-Marseille University, Marseille, France.
9 Institut National de la Recherche Agronomique, USC 1408 AFMB, Marseille, France.
10 Department of Biological Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
11 Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
12 Fungal Molecular Physiology, Utrecht University, Utrecht, The Netherlands.

Description:

The obligate alkalophilic soda-lake fungus Sodiomyces alkalinus has shifted to a protein diet.

Mol Ecol. 2018 12;27(23):4808-4819

Authors: Grum-Grzhimaylo AA, Falkoski DL, van den Heuvel J, Valero-Jiménez CA, Min B, Choi IG, Lipzen A, Daum CG, Aanen DK, Tsang A, Henrissat B, Bilanenko EN, de Vries RP, van Kan JAL, Grigoriev IV, Debets AJM

Abstract

Sodiomyces alkalinus is one of the very few alkalophilic fungi, adapted to grow optimally at high pH. It is widely distributed at the plant-deprived edges of extremely alkaline lakes and locally abundant. We sequenced the genome of S. alkalinus and reconstructed evolution of catabolic enzymes, using a phylogenomic comparison. We found that the genome of S. alkalinus is larger, but its predicted proteome is smaller and heavily depleted of both plant-degrading enzymes and proteinases, when compared to its closest plant-pathogenic relatives. Interestingly, despite overall losses, S. alkalinus has retained many proteinases families and acquired bacterial cell wall-degrading enzymes, some of them via horizontal gene transfer from bacteria. This fungus has very potent proteolytic activity at high pH values, but slowly induced low activity of cellulases and hemicellulases. Our experimental and in silico data suggest that plant biomass, a common food source for most fungi, is not a preferred substrate for S. alkalinus in its natural environment. We conclude that the fungus has abandoned the ancestral plant-based diet and has become specialized in a more protein-rich food, abundantly available in soda lakes in the form of prokaryotes and small crustaceans.

PMID: 30368956 [PubMed - in process]