Keyword search (3,619 papers available)


Energy loss associated with in-vitro modeling of mitral annular calcification.

Author(s): Wiener PC, Darwish A, Friend E, Kadem L, Pressman GS

INTRODUCTION: Study aims were to compare hemodynamics and viscous energy dissipation (VED) in 3D printed mitral valves-one replicating a normal valve and the other a valve with severe mitral annular calcification (MAC). Patients with severe MAC develop tran...

Article GUID: 33591991
The need for exercise sciences and an integrated response to COVID-19: A position statement from the international HL-PIVOT network.

Author(s): Faghy MA, Arena R, Stoner L, Haraf RH, Josephson R, Hills AP, Dixit S, Popovic D, Smith A, Myers J, Bacon SL, Niebauer J, Dourado VZ, Babu A...

COVID-19 is one of the biggest health crises that the world has seen. Whilst measures to abate transmission and infection are ongoing, there continues to be growing numbers of patients requiring ch...

Article GUID: 33549590
Proper Orthogonal Decomposition Analysis of the Flow Downstream of a Dysfunctional Bileaflet Mechanical Aortic Valve.

Author(s): Darwish A, Di Labbio G, Saleh W, Kadem L

PURPOSE: Aortic valve replacement remains the only viable solution for symptomatic patients with severe aortic valve stenosis. Despite their improved design and long history of successful operation, bileaflet mechanical heart valves are still associated wit...

Article GUID: 33469847
Impact of Mitral Regurgitation on the Flow in a Model of a Left Ventricle.

Author(s): Papolla C, Darwish A, Kadem L, Rieu R

PURPOSE: Mitral regurgitation (MR) is the second most common valve disease in industrialized countries. Despite its high prevalence, little is known about its impact on the flow dynamics in the left ventricle (LV). Because of the interdependence between val...

Article GUID: 33000444
Impact of fluorination on interface energetics and growth of pentacene on Ag(111).

Author(s): Wang Q, Chen MT, Franco-Cañellas A, Shen B, Geiger T, F Bettinger H, Schreiber F, Salzmann I, Gerlach A, Duhm S...

We studied the structural and electronic properties of 2,3,9,10-tetrafluoropentacene (F4PEN) on Ag(111) via X-ray standing waves (XSW), low-energy electron diffraction (LEED) as well as ultraviolet...

Article GUID: 32974114
Improving Safety of MRI in Patients with Deep Brain Stimulation Devices.

Author(s): Boutet A, Chow CT, Narang K, Elias GJB, Neudorfer C, Germann J, Ranjan M, Loh A, Martin AJ, Kucharczyk W, Steele CJ, Hancu I, Rezai AR, Lozano AM

Radiology. 2020 Jun 23;:192291 Authors: Boutet A, Chow CT, Narang K, Elias GJB, Neudorfer C, Germann J, Ranjan M, Loh A, Martin AJ, Kucharczyk W, Steele CJ, Hancu I, Rezai AR, Lozano AM

Article GUID: 32573388
Modular Construction of Porous Hydrogen-Bonded  Molecular Materials from Melams.

Author(s): Khadivjam T, Che-Quang H, Maris T, Ajoyan Z, Howarth A, Wuest JD

Chemistry. 2020 Mar 01;: Authors: Khadivjam T, Che-Quang H, Maris T, Ajoyan Z, Howarth A, Wuest JD

Article GUID: 32115786
Metabolic networks of the human gut microbiota.

Author(s): Selber-Hnatiw S, Sultana T, Tse W, Abdollahi N, Abdullah S, Al Rahbani J, Alazar D, Alrumhein NJ, Aprikian S, Arshad R, Azuelos JD, Bernadot...

Metabolic networks of the human gut microbiota.

Microbiology. 2019 Dec 04;:

Authors: Selber-Hnatiw S, Sultana T, Tse W, Abdollahi N, Abdullah S, Al Rahbani J, Alazar D, Alrumhei...

Article GUID: 31799915
Nano-Bio Interactions of Extracellular Vesicles with Gold Nanoislands for Early Cancer Diagnosis.

Author(s): Bathini S, Raju D, Badilescu S, Kumar A, Ouellette RJ, Ghosh A, Packirisamy M

Res (Wash D C). 2018;2018:3917986 Authors: Bathini S, Raju D, Badilescu S, Kumar A, Ouellette RJ, Ghosh A, Packirisamy M

Article GUID: 31549028
Dielectrophoresis Multipath Focusing of Microparticles through Perforated Electrodes in Microfluidic Channels.

Author(s): Alazzam A, Al-Khaleel M, Riahi MK, Mathew B, Gawanmeh A, Nerguizian V

Biosensors (Basel). 2019 Aug 07;9(3): Authors: Alazzam A, Al-Khaleel M, Riahi MK, Mathew B, Gawanmeh A, Nerguizian V

Article GUID: 31394810
The priming effect of food persists following blockade of dopamine receptors.

Author(s): Evangelista C, Hantson A, Shams WM, Almey A, Pileggi M, Voisard JR, Boulos V, Al-Qadri Y, Gonzalez Cautela BV, Zhou FX, Duchemin J, Habrich ...

Eur J Neurosci. 2019 Jul 27;: Authors: Evangelista C, Hantson A, Shams WM, Almey A, Pileggi M, Voisard JR, Boulos V, Al-Qadri Y, Gonzalez Cautela BV, Zhou FX, Duchemin J, Habrich A, Tito N, Koumro...

Article GUID: 31350860
Lithocholic bile acid accumulated in yeast mitochondria orchestrates a development of an anti-aging cellular pattern by causing age-related changes in cellular proteome.

Author(s): Beach A, Richard VR, Bourque S, Boukh-Viner T, Kyryakov P, Gomez-Perez A, Arlia-Ciommo A, Feldman R, Leonov A, Piano A, Svistkova V, Titorenko VI

Cell Cycle. 2015;14(11):1643-56 Authors: Beach A, Richard VR, Bourque S, Boukh-Viner T, Kyryakov P, Gomez-Perez A, Arlia-Ciommo A, Feldman R, Leonov A, Piano A, Svistkova V, Titorenko VI

Article GUID: 25839782
Caloric restriction delays yeast chronological aging by remodeling carbohydrate and lipid metabolism, altering peroxisomal and mitochondrial functionalities, and postponing the onsets of apoptotic and liponecrotic modes of regulated cell death.

Author(s): Arlia-Ciommo A, Leonov A, Beach A, Richard VR, Bourque SD, Burstein MT, Kyryakov P, Gomez-Perez A, Koupaki O, Feldman R, Titorenko VI

Oncotarget. 2018 Mar 23;9(22):16163-16184 Authors: Arlia-Ciommo A, Leonov A, Beach A, Richard VR, Bourque SD, Burstein MT, Kyryakov P, Gomez-Perez A, Koupaki O, Feldman R, Titorenko VI

Article GUID: 29662634
Genetic combining ability of coriander genotypes for agronomic and phytochemical traits in response to contrasting irrigation regimes.

Author(s): Gholizadeh A, Dehghani H, Khodadadi M, Gulick PJ

PLoS One. 2018;13(6):e0199630 Authors: Gholizadeh A, Dehghani H, Khodadadi M, Gulick PJ

Article GUID: 29953470
Mechanisms through which lithocholic acid delays yeast chronological aging under caloric restriction conditions.

Author(s): Arlia-Ciommo A, Leonov A, Mohammad K, Beach A, Richard VR, Bourque SD, Burstein MT, Goldberg AA, Kyryakov P, Gomez-Perez A, Koupaki O, Titorenko VI

Oncotarget. 2018 Oct 09;9(79):34945-34971 Authors: Arlia-Ciommo A, Leonov A, Mohammad K, Beach A, Richard VR, Bourque SD, Burstein MT, Goldberg AA, Kyryakov P, Gomez-Perez A, Koupaki O, Titorenko VI

Article GUID: 30405886
Geo-referenced population-specific microsatellite data across American continents, the MacroPopGen Database.

Author(s): Lawrence ER, Benavente JN, Matte JM, Marin K, Wells ZRR, Bernos TA, Krasteva N, Habrich A, Nessel GA, Koumrouyan RA, Fraser DJ

Sci Data. 2019 04 03;6(1):14 Authors: Lawrence ER, Benavente JN, Matte JM, Marin K, Wells ZRR, Bernos TA, Krasteva N, Habrich A, Nessel GA, Koumrouyan RA, Fraser DJ

Article GUID: 30944329
Experimental investigation of the flow downstream of a dysfunctional bileaflet mechanical aortic valve.

Author(s): Darwish A, Di Labbio G, Saleh W, Smadi O, Kadem L

Artif Organs. 2019 May 08;: Authors: Darwish A, Di Labbio G, Saleh W, Smadi O, Kadem L

Article GUID: 31066923
Synthesis of Highly Functionalized Triarylbismuthines by Functional Group Manipulation and Use in Palladium- and Copper-Catalyzed Arylation Reactions.

Author(s): Hébert M, Petiot P, Benoit E, Dansereau J, Ahmad T, Le Roch A, Ottenwaelder X, Gagnon A

J Org Chem. 2016 07 01;81(13):5401-16 Authors: Hébert M, Petiot P, Benoit E, Dansereau J, Ahmad T, Le Roch A, Ottenwaelder X, Gagnon A

Article GUID: 27231755
Pyrrole and Fused Pyrrole Compounds with Bioactivity against Inflammatory Mediators.

Author(s): Said Fatahala S, Hasabelnaby S, Goudah A, Mahmoud GI, Helmy Abd-El Hameed R

Molecules. 2017 Mar 17;22(3): Authors: Said Fatahala S, Hasabelnaby S, Goudah A, Mahmoud GI, Helmy Abd-El Hameed R

Article GUID: 28304349
Are Magnetic Resonance Imaging Technologies Crucial to Our Understanding of Spinal Conditions?

Author(s): Crawford RJ, Fortin M, Weber KA, Smith A, Elliott JM

Are Magnetic Resonance Imaging Technologies Crucial to Our Understanding of Spinal Conditions?

J Orthop Sports Phys Ther. 2019 Mar 26;:1-32

Authors: Crawford RJ, Fortin M, Weber KA, Smith A, Elliott JM

Abstract
SYNOPSIS: T...

Article GUID: 30913967
Title:Impact of Mitral Regurgitation on the Flow in a Model of a Left Ventricle.
Authors:Papolla C,  Darwish A,  Kadem L,  Rieu R
Link:https://www.ncbi.nlm.nih.gov/pubmed/33000444
DOI:10.1007/s13239-020-00490-y
Category:Cardiovasc Eng Technol
PMID:33000444
Dept Affiliation: ENCS
1 Aix-Marseille University, Gustave Eiffel University, LBA UMR_T 24, Marseille, France.
2 Képhalios, part of Affluent Medical Group, Aix-en-Provence, France.
3 Laboratory of Cardiovascular Fluid Dynamics, Mechanical, Industrial and Aerospace Engineering, Concordia University, Montréal, QC, Canada.
4 Aix-Marseille University, Gustave Eiffel University, LBA UMR_T 24, Marseille, France. regis.rieu@univ-amu.fr.
5 Laboratoire de Biomécanique Appliquée, Bd. P. Dramard, Faculté de Medecine secteur-Nord, 13916, Marseille Cedex 20, France. regis.rieu@univ-amu.fr.

Description:

Impact of Mitral Regurgitation on the Flow in a Model of a Left Ventricle.

Cardiovasc Eng Technol. 2020 Sep 30; :

Authors: Papolla C, Darwish A, Kadem L, Rieu R

Abstract

PURPOSE: Mitral regurgitation (MR) is the second most common valve disease in industrialized countries. Despite its high prevalence, little is known about its impact on the flow dynamics in the left ventricle (LV). Because of the interdependence between valvular function and hemodynamics in the heart chambers, an exploration of the dynamics in the LV could lead to a diagnosis of MR. This in vitro study aimed to develop an advanced left heart simulator capable of reproducing several conditions of MR and to evaluate their impact on the LV flow dynamics in terms of flow structures and viscous energy dissipation (VED).

METHODS: A simulator, previously developed to test mechanical and biological valves, was upgraded with an original anatomically-shaped mitral valve made from a hydrogel. The valve can be used in healthy or pathological configurations. The nature and severity of the disease was controlled by applying specific strain to the chordae. In this study, in addition to a healthy condition, two different severities of MR were investigated: moderate MR and severe MR. Planar time-resolved particle image velocimetry measurements were performed in order to evaluate the velocity field in the LV and the VED induced by each condition.

RESULTS: Our results showed that MR led to flow disturbances in the LV that were characterized by an increase in mitral inflow velocity and by elevated values of VED. Interestingly VED increased in proportion to the severity of MR and with a dissipation predominating during systole.

CONCLUSION: Considering these results, the introduction of new parameters based on LV VED could provide crucial information regarding the coupling between the mitral valve and the LV and allow for a better stratification of patients with MR.

PMID: 33000444 [PubMed - as supplied by publisher]