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Neural correlates of resilience to the effects of hippocampal atrophy on memory.

Author(s): Belleville S, Mellah S, Cloutier S, Dang-Vu TT, Duchesne S, Maltezos S, Phillips N, Hudon C, CIMA-Q group...

INTRODUCTION: Cognitive reserve can be defined as a property of the brain that enables an individual to sustain cognitive performance in spite of age-related neural changes. This study uses brain i...

Article GUID: 33360019
Behavioral and Psychological Symptoms that Predict Cognitive Decline or Impairment in Cognitively Normal Middle-Aged or Older Adults: a Meta-Analysis.

Author(s): Hudon C, Escudier F, De Roy J, Croteau J, Cross N, Dang-Vu TT, Zomahoun HTV, Grenier S, Gagnon JF, Parent A, Bruneau MA, Belleville S, Conso...

Neuropsychol Rev. 2020 May 11;: Authors: Hudon C, Escudier F, De Roy J, Croteau J, Cross N, Dang-Vu TT, Zomahoun HTV, Grenier S, Gagnon JF, Parent A, Bruneau MA, Belleville S, Consortium for the E...

Article GUID: 32394109
The Impairment of Number Transcoding Abilities in Individuals with Amnestic Mild Cognitive Impairment and Alzheimer Disease: Associations With Attentional and Executive Functions.

Author(s): Macoir J, Lafay A, Hudon C

Cogn Behav Neurol. 2020 Mar;33(1):33-44 Authors: Macoir J, Lafay A, Hudon C

Article GUID: 32132401
Drivers with Amnestic Mild Cognitive Impairment Can Benefit from a Multiple-Session Driving Simulator Automated Training Program.

Author(s): Teasdale N, Simoneau M, Hudon L, Moszkowicz T, Laurendeau D, Germain Robitaille M, Bherer L, Duchesne S, Hudon C

J Am Geriatr Soc. 2016 09;64(9):e16-8 Authors: Teasdale N, Simoneau M, Hudon L, Moszkowicz T, Laurendeau D, Germain Robitaille M, Bherer L, Duchesne S, Hudon C PMID: 27564992 [PubMed - indexed for MEDLINE]

Article GUID: 27564992
Title:The Impairment of Number Transcoding Abilities in Individuals with Amnestic Mild Cognitive Impairment and Alzheimer Disease: Associations With Attentional and Executive Functions.
Authors:Macoir J,  Lafay A,  Hudon C
Link:https://www.ncbi.nlm.nih.gov/pubmed/32132401?dopt=Abstract
DOI:10.1097/WNN.0000000000000225
Category:Cogn Behav Neurol
PMID:32132401
Dept Affiliation: MATHSTATS
1 Faculty of Medicine, Department of Rehabilitation.
2 CERVO Brain Research Centre, Québec, Canada.
3 Mathematics Teaching and Learning Lab, Concordia University, Montreal, Canada.
4 School of Psychology, Laval University, Québec, Canada.

Description:

The Impairment of Number Transcoding Abilities in Individuals with Amnestic Mild Cognitive Impairment and Alzheimer Disease: Associations With Attentional and Executive Functions.

Cogn Behav Neurol. 2020 Mar;33(1):33-44

Authors: Macoir J, Lafay A, Hudon C

Abstract

BACKGROUND: Studies have shown that number transcoding abilities (ie, translating numbers from one numerical code to another) are affected early in the development of Alzheimer disease (AD). However, no study has extensively explored how these abilities are affected in individuals with mild cognitive impairment (MCI).

OBJECTIVE: To determine the contribution that number transcoding tasks make to the identification of MCI, and to pinpoint the cognitive correlates of performance in these tasks.

METHODS: We compared the performance of 20 individuals with the amnestic subtype of MCI, eight individuals with AD, and 20 healthy controls on three number transcoding tasks.

RESULTS: The results confirmed the presence of number transcoding impairment in the individuals with AD. The individuals with MCI were found to be impaired in two of the transcoding tasks; these individuals produced perseverations of the input code-the most noteworthy error type in individuals with AD. In addition, the relationship between impairment in attentional and executive functions and impairment in number transcoding was supported by the correlational analyses.

CONCLUSIONS: This study confirmed that number transcoding abilities are impaired in individuals with MCI, although less severely than in individuals with AD. Our results provide evidence for the clinical value of including number transcoding tasks in the assessment of cognitive deficits associated with pathological aging.

PMID: 32132401 [PubMed - in process]