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The standard reconsolidation protocol for auditory fear-conditioning does not account for fear to the test context

Author(s): Jason W Payne

Research on memory reconsolidation has relied heavily on the use of Pavlovian auditory cued-fear conditioning. Here, an auditory cue (CS) is paired with a footshock (US) and the CS is later able to evoke a freezing response when presented alone. Some treatm...

Article GUID: 37347748


Title:The standard reconsolidation protocol for auditory fear-conditioning does not account for fear to the test context
Authors:Jason W Payne
Link:https://pubmed.ncbi.nlm.nih.gov/37347748/
DOI:10.1371/journal.pone.0287193
Category:
PMID:37347748
Dept Affiliation: CSBN

Description:

Research on memory reconsolidation has relied heavily on the use of Pavlovian auditory cued-fear conditioning. Here, an auditory cue (CS) is paired with a footshock (US) and the CS is later able to evoke a freezing response when presented alone. Some treatments, when administered to conditioned subjects immediately following a CS-alone (memory reactivation) trial, can attenuate the freezing they display on subsequent CS-alone (test) trials, in the absence of the treatment. This reduction in...