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Author(s): Jason W Payne
Research on memory reconsolidation has relied heavily on the use of Pavlovian auditory cued-fear conditioning. Here, an auditory cue (CS) is paired with a footshock (US) and the CS is later able to evoke a freezing response when presented alone. Some treatm...
Article GUID: 37347748
Title: | The standard reconsolidation protocol for auditory fear-conditioning does not account for fear to the test context |
Authors: | Jason W Payne |
Link: | https://pubmed.ncbi.nlm.nih.gov/37347748/ |
DOI: | 10.1371/journal.pone.0287193 |
Category: | |
PMID: | 37347748 |
Dept Affiliation: | CSBN |
Description: |
Research on memory reconsolidation has relied heavily on the use of Pavlovian auditory cued-fear conditioning. Here, an auditory cue (CS) is paired with a footshock (US) and the CS is later able to evoke a freezing response when presented alone. Some treatments, when administered to conditioned subjects immediately following a CS-alone (memory reactivation) trial, can attenuate the freezing they display on subsequent CS-alone (test) trials, in the absence of the treatment. This reduction in... |