Keyword search (3,619 papers available)


Sex differences in the relationship between dietary pattern adherence and cognitive function among older adults: findings from the NuAge study.

Author(s): D'Amico D, Parrott MD, Greenwood CE, Ferland G, Gaudreau P, Belleville S, Laurin D, Anderson ND, Kergoat MJ, Morais JA, Presse N, Fiocco AJ,

Nutr J. 2020 Jun 20;19(1):58 Authors: D'Amico D, Parrott MD, Greenwood CE, Ferland G, Gaudreau P, Belleville S, Laurin D, Anderson ND, Kergoat MJ, Morais JA, Presse N, Fiocco AJ

Article GUID: 32563260
Brain perfusion during rapid-eye-movement sleep successfully identifies amnestic mild cognitive impairment.

Author(s): Brayet P, Petit D, Baril AA, Gosselin N, Gagnon JF, Soucy JP, Gauthier S, Kergoat MJ, Carrier J, Rouleau I, Montplaisir J

Sleep Med. 2017 Jun;34:134-140 Authors: Brayet P, Petit D, Baril AA, Gosselin N, Gagnon JF, Soucy JP, Gauthier S, Kergoat MJ, Carrier J, Rouleau I, Montplaisir J

Article GUID: 28522082
Relationships between lower body strength and the energy cost of treadmill walking in a cohort of healthy older adults: a cross-sectional analysis.

Author(s): Berryman N, Bherer L, Nadeau S, Lauzière S, Lehr L, Bobeuf F, Kergoat MJ, Vu TT, Bosquet L

Eur J Appl Physiol. 2017 Jan;117(1):53-59 Authors: Berryman N, Bherer L, Nadeau S, Lauzière S, Lehr L, Bobeuf F, Kergoat MJ, Vu TT, Bosquet L

Article GUID: 27815704
A comparison of the impact of physical exercise, cognitive training and combined intervention on spontaneous walking speed in older adults.

Author(s): Pothier K, Gagnon C, Fraser SA, Lussier M, Desjardins-Crépeau L, Berryman N, Kergoat MJ, Vu TTM, Li KZH, Bosquet L, Bherer L

Aging Clin Exp Res. 2018 Aug;30(8):921-925 Authors: Pothier K, Gagnon C, Fraser SA, Lussier M, Desjardins-Crépeau L, Berryman N, Kergoat MJ, Vu TTM, Li KZH, Bosquet L, Bherer L

Article GUID: 29235076
Title:Brain perfusion during rapid-eye-movement sleep successfully identifies amnestic mild cognitive impairment.
Authors:Brayet P,  Petit D,  Baril AA,  Gosselin N,  Gagnon JF,  Soucy JP,  Gauthier S,  Kergoat MJ,  Carrier J,  Rouleau I,  Montplaisir J
Link:https://www.ncbi.nlm.nih.gov/pubmed/28522082?dopt=Abstract
DOI:10.1016/j.sleep.2017.01.025
Category:Sleep Med
PMID:28522082
Dept Affiliation: PERFORM
1 Department of Psychology, Université du Québec à Montréal, Montréal, Canada; Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Coeur de Montréal, Montréal, Canada.
2 Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Coeur de Montréal, Montréal, Canada.
3 Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Coeur de Montréal, Montréal, Canada; Faculty of Medicine, Université de Montréal, Montréal, Canada.
4 Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Coeur de Montréal, Montréal, Canada; Department of Psychology, Université de Montréal, Montréal, Canada.
5 Montreal Neurological Institute, McGill University, Montréal, Canada; PERFORM Centre, Concordia University, Montréal, Canada.
6 McGill University Research Centre for Studies in Aging, Douglas Hospital, Verdun, Canada.
7 Faculty of Medicine, Université de Montréal, Montréal, Canada; Research Center, Institut universitaire de gériatrie de Montréal, Montreal, Canada.
8 Department of Psychology, Université du Québec à Montréal, Montréal, Canada; Neurology Service, Hôpital Notre-Dame du CHUM, Montréal, Canada.
9 Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Coeur de Montréal, Montréal, Canada; Faculty of Medicine, Université de Montréal, Montréal, Canada. Electronic address: jy.montplaisir@umontreal.ca.

Description:

Brain perfusion during rapid-eye-movement sleep successfully identifies amnestic mild cognitive impairment.

Sleep Med. 2017 Jun;34:134-140

Authors: Brayet P, Petit D, Baril AA, Gosselin N, Gagnon JF, Soucy JP, Gauthier S, Kergoat MJ, Carrier J, Rouleau I, Montplaisir J

Abstract

INTRODUCTION: Prodromal markers of Alzheimer's disease (AD) have been derived from wakefulness. However, brain perfusion during rapid-eye movement (REM) sleep could be a sensitive marker of amnestic mild cognitive impairment (aMCI), as activation of REM sleep relies more on the cholinergic system.

METHODS: Eight subjects with aMCI, and 16 controls, underwent two single-photon emission computed tomography (SPECT) scans with tracer injected during REM sleep then wakefulness.

RESULTS: Perfusion in the anterior cingulate cortex was significantly decreased in aMCI cases compared to controls for both conditions. That defect was much larger and more severe in REM sleep (1795 voxels) compared to wakefulness (398 voxels), and extended to the middle cingulate cortex and the olfactory cortex. Hypoperfusion in the anterior cingulate cortex during REM sleep allowed better classification than hypoperfusion found in wakefulness (93.8 vs 81.3%).

CONCLUSION: REM sleep imaging is a valuable tool with which to identify individuals at risk of developing AD.

PMID: 28522082 [PubMed - indexed for MEDLINE]