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Acceptability of a structured diet and exercise weight loss intervention in breast cancer survivors living with an overweight condition or obesity: A qualitative analysis.

Author(s): Beckenstein H, Slim M, Kim H, Plourde H, Kilgour R, Cohen TR

BACKGROUND: Weight loss increases survivorship following breast cancer diagnosis. However, most breast cancer survivors (BCS) do not meet diet and exercise recommendations. AIM: The purpose of this study was to explore the barriers and facilitators of BCS w...

Article GUID: 33491338
Beyond sleepy: structural and functional changes of the default-mode network in idiopathic hypersomnia.

Author(s): Pomares FB, Boucetta S, Lachapelle F, Steffener J, Montplaisir J, Cha J, Kim H, Dang-Vu TT

Sleep. 2019 Jul 22;: Authors: Pomares FB, Boucetta S, Lachapelle F, Steffener J, Montplaisir J, Cha J, Kim H, Dang-Vu TT

Article GUID: 31328786
Caloric restriction extends yeast chronological lifespan via a mechanism linking cellular aging to cell cycle regulation, maintenance of a quiescent state, entry into a non-quiescent state and survival in the non-quiescent state.

Author(s): Leonov A, Feldman R, Piano A, Arlia-Ciommo A, Lutchman V, Ahmadi M, Elsaser S, Fakim H, Heshmati-Moghaddam M, Hussain A, Orfali S, Rajen H, ...

Oncotarget. 2017 Sep 19;8(41):69328-69350 Authors: Leonov A, Feldman R, Piano A, Arlia-Ciommo A, Lutchman V, Ahmadi M, Elsaser S, Fakim H, Heshmati-Moghaddam M, Hussain A, Orfali S, Rajen H, Roofi...

Article GUID: 29050207
Cortical Thinning and Altered Cortico-Cortical Structural Covariance of the Default Mode Network in Patients with Persistent Insomnia Symptoms.

Author(s): Suh S, Kim H, Dang-Vu TT, Joo E, Shin C

Sleep. 2016 Jan 01;39(1):161-71 Authors: Suh S, Kim H, Dang-Vu TT, Joo E, Shin C

Article GUID: 26414892
Title:Cortical Thinning and Altered Cortico-Cortical Structural Covariance of the Default Mode Network in Patients with Persistent Insomnia Symptoms.
Authors:Suh S,  Kim H,  Dang-Vu TT,  Joo E,  Shin C
Link:https://www.ncbi.nlm.nih.gov/pubmed/26414892?dopt=Abstract
DOI:10.5665/sleep.5340
Category:Sleep
PMID:26414892
Dept Affiliation: PERFORM
1 Sungshin Women's University, Department of Psychology, Seoul, Korea.
2 Stanford University, Department of Psychiatry, Palo Alto, CA.
3 University of California San Francisco, Department of Radiology and Biomedical Imaging, San Francisco, CA.
4 Center for Studies in Behavioral Neurobiology, PERFORM Center & Department of Exercise Science, Concordia University, Montreal, Canada.
5 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal & Department of Neurosciences, University of Montreal, Montreal, Canada.
6 Samsung Medical Center, Department of Neurology, Sungkyunkwan University School of Medicine, Seoul, Korea.
7 Korea University Ansan Hospital, Institute of Human Genomic Study, Seoul, Korea.
8 Korea University Ansan Hospital, Department of Internal Medicine, Seoul, Korea.

Description:

Cortical Thinning and Altered Cortico-Cortical Structural Covariance of the Default Mode Network in Patients with Persistent Insomnia Symptoms.

Sleep. 2016 Jan 01;39(1):161-71

Authors: Suh S, Kim H, Dang-Vu TT, Joo E, Shin C

Abstract

STUDY OBJECTIVES: Recent studies have suggested that structural abnormalities in insomnia may be linked with alterations in the default-mode network (DMN). This study compared cortical thickness and structural connectivity linked to the DMN in patients with persistent insomnia (PI) and good sleepers (GS).

METHODS: The current study used a clinical subsample from the longitudinal community-based Korean Genome and Epidemiology Study (KoGES). Cortical thickness and structural connectivity linked to the DMN in patients with persistent insomnia symptoms (PIS; n = 57) were compared to good sleepers (GS; n = 40). All participants underwent MRI acquisition. Based on literature review, we selected cortical regions corresponding to the DMN. A seed-based structural covariance analysis measured cortical thickness correlation between each seed region of the DMN and other cortical areas. Association of cortical thickness and covariance with sleep quality and neuropsychological assessments were further assessed.

RESULTS: Compared to GS, cortical thinning was found in PIS in the anterior cingulate cortex, precentral cortex, and lateral prefrontal cortex. Decreased structural connectivity between anterior and posterior regions of the DMN was observed in the PIS group. Decreased structural covariance within the DMN was associated with higher PSQI scores. Cortical thinning in the lateral frontal lobe was related to poor performance in executive function in PIS.

CONCLUSION: Disrupted structural covariance network in PIS might reflect malfunctioning of antero-posterior disconnection of the DMN during the wake to sleep transition that is commonly found during normal sleep. The observed structural network alteration may further implicate commonly observed sustained sleep difficulties and cognitive impairment in insomnia.

PMID: 26414892 [PubMed - indexed for MEDLINE]