Keyword search (3,168 papers available)


Large-scale mGluR5 network abnormalities linked to epilepsy duration in focal cortical dysplasia.

Author(s): DuBois JM, Mathotaarachchi S, Rousset OG, Sziklas V, Sepulcre J, Guiot MC, Hall JA, Massarweh G, Soucy JP, Rosa-Neto P, Kobayashi E...

To determine the extent of metabotropic glutamate receptor type 5 (mGluR5) network abnormalities associated with focal cortical dysplasia (FCD), we performed graph theoretical analysis of [11C]ABP6...

Article GUID: 33401137
Effects of Independent Component Analysis on Magnetoencephalography Source Localization in Pre-surgical Frontal Lobe Epilepsy Patients

Author(s): Pellegrino G, Xu M, Alkuwaiti A, Porras-Bettancourt M, Abbas G, Lina JM, Grova C, Kobayashi E,...

Objective: Magnetoencephalography source imaging (MSI) of interictal epileptiform discharges (IED) is a useful presurgical tool in the evaluation of drug-resistant frontal lobe epilepsy (FLE) patie...

Article GUID: 32582009
Accuracy and spatial properties of distributed magnetic source imaging techniques in the investigation of focal epilepsy patients.

Author(s): Pellegrino G, Hedrich T, Porras-Bettancourt M, Lina JM, Aydin Ü, Hall J, Grova C, Kobayashi E

Hum Brain Mapp. 2020 May 09;: Authors: Pellegrino G, Hedrich T, Porras-Bettancourt M, Lina JM, Aydin Ü, Hall J, Grova C, Kobayashi E

Article GUID: 32386115
Magnetoencephalography resting state connectivity patterns as indicatives of surgical outcome in epilepsy patients.

Author(s): Aydin Ü, Pellegrino G, Bin Ka'b Ali O, Abdallah C, Dubeau F, Lina JM, Kobayashi E, Grova C

J Neural Eng. 2020 Mar 18;: Authors: Aydin Ü, Pellegrino G, Bin Ka'b Ali O, Abdallah C, Dubeau F, Lina JM, Kobayashi E, Grova C

Article GUID: 32191632
Inferior Longitudinal Fasciculus' Role in Visual Processing and Language Comprehension: A Combined MEG-DTI Study.

Author(s): Shin J, Rowley J, Chowdhury R, Jolicoeur P, Klein D, Grova C, Rosa-Neto P, Kobayashi E

Front Neurosci. 2019;13:875 Authors: Shin J, Rowley J, Chowdhury R, Jolicoeur P, Klein D, Grova C, Rosa-Neto P, Kobayashi E

Article GUID: 31507359
Localization Accuracy of Distributed Inverse Solutions for Electric and Magnetic Source Imaging of Interictal Epileptic Discharges in Patients with Focal Epilepsy.

Author(s): Heers M, Chowdhury RA, Hedrich T, Dubeau F, Hall JA, Lina JM, Grova C, Kobayashi E

Brain Topogr. 2016 Jan;29(1):162-81 Authors: Heers M, Chowdhury RA, Hedrich T, Dubeau F, Hall JA, Lina JM, Grova C, Kobayashi E

Article GUID: 25609211
MEG-EEG Information Fusion and Electromagnetic Source Imaging: From Theory to Clinical Application in Epilepsy.

Author(s): Chowdhury RA, Zerouali Y, Hedrich T, Heers M, Kobayashi E, Lina JM, Grova C

Brain Topogr. 2015 Nov;28(6):785-812 Authors: Chowdhury RA, Zerouali Y, Hedrich T, Heers M, Kobayashi E, Lina JM, Grova C

Article GUID: 26016950
Detection and Magnetic Source Imaging of Fast Oscillations (40-160 Hz) Recorded with Magnetoencephalography in Focal Epilepsy Patients.

Author(s): von Ellenrieder N, Pellegrino G, Hedrich T, Gotman J, Lina JM, Grova C, Kobayashi E

Brain Topogr. 2016 Mar;29(2):218-31 Authors: von Ellenrieder N, Pellegrino G, Hedrich T, Gotman J, Lina JM, Grova C, Kobayashi E

Article GUID: 26830767
Intracranial EEG potentials estimated from MEG sources: A new approach to correlate MEG and iEEG data in epilepsy.

Author(s): Grova C, Aiguabella M, Zelmann R, Lina JM, Hall JA, Kobayashi E

Hum Brain Mapp. 2016 May;37(5):1661-83 Authors: Grova C, Aiguabella M, Zelmann R, Lina JM, Hall JA, Kobayashi E

Article GUID: 26931511
Source localization of the seizure onset zone from ictal EEG/MEG data.

Author(s): Pellegrino G, Hedrich T, Chowdhury R, Hall JA, Lina JM, Dubeau F, Kobayashi E, Grova C

Hum Brain Mapp. 2016 07;37(7):2528-46 Authors: Pellegrino G, Hedrich T, Chowdhury R, Hall JA, Lina JM, Dubeau F, Kobayashi E, Grova C

Article GUID: 27059157
Clinical yield of magnetoencephalography distributed source imaging in epilepsy: A comparison with equivalent current dipole method.

Author(s): Pellegrino G, Hedrich T, Chowdhury RA, Hall JA, Dubeau F, Lina JM, Kobayashi E, Grova C

Hum Brain Mapp. 2018 01;39(1):218-231 Authors: Pellegrino G, Hedrich T, Chowdhury RA, Hall JA, Dubeau F, Lina JM, Kobayashi E, Grova C

Article GUID: 29024165
Reproducibility of EEG-MEG fusion source analysis of interictal spikes: Relevance in presurgical evaluation of epilepsy.

Author(s): Chowdhury RA, Pellegrino G, Aydin Ü, Lina JM, Dubeau F, Kobayashi E, Grova C

Hum Brain Mapp. 2018 02;39(2):880-901 Authors: Chowdhury RA, Pellegrino G, Aydin Ü, Lina JM, Dubeau F, Kobayashi E, Grova C

Article GUID: 29164737
Optimal positioning of optodes on the scalp for personalized functional near-infrared spectroscopy investigations.

Author(s): Machado A, Cai Z, Pellegrino G, Marcotte O, Vincent T, Lina JM, Kobayashi E, Grova C

J Neurosci Methods. 2018 Nov 01;309:91-108 Authors: Machado A, Cai Z, Pellegrino G, Marcotte O, Vincent T, Lina JM, Kobayashi E, Grova C

Article GUID: 30107210
Complex patterns of spatially extended generators of epileptic activity: Comparison of source localization methods cMEM and 4-ExSo-MUSIC on high resolution EEG and MEG data.

Author(s): Chowdhury RA, Merlet I, Birot G, Kobayashi E, Nica A, Biraben A, Wendling F, Lina JM, Albera L, Grova C...

Complex patterns of spatially extended generators of epileptic activity: Comparison of source localization methods cMEM and 4-ExSo-MUSIC on high resolution EEG and MEG data.

Neuroimage. 2...

Article GUID: 27561712
Metabotropic Glutamate Receptor Type 5 (mGluR5) Cortical Abnormalities in Focal Cortical Dysplasia Identified In Vivo With [11C]ABP688 Positron-Emission Tomography (PET) Imaging.

Author(s): DuBois JM, Rousset OG, Guiot MC, Hall JA, Reader AJ, Soucy JP, Rosa-Neto P, Kobayashi E

Cereb Cortex. 2016 10 17;26(11):4170-4179 Authors: DuBois JM, Rousset OG, Guiot MC, Hall JA, Reader AJ, Soucy JP, Rosa-Neto P, Kobayashi E

Article GUID: 27578494
Comparison of the spatial resolution of source imaging techniques in high-density EEG and MEG.

Author(s): Hedrich T, Pellegrino G, Kobayashi E, Lina JM, Grova C

Neuroimage. 2017 08 15;157:531-544 Authors: Hedrich T, Pellegrino G, Kobayashi E, Lina JM, Grova C

Article GUID: 28619655
Title:Localization Accuracy of Distributed Inverse Solutions for Electric and Magnetic Source Imaging of Interictal Epileptic Discharges in Patients with Focal Epilepsy.
Authors:Heers M,  Chowdhury RA,  Hedrich T,  Dubeau F,  Hall JA,  Lina JM,  Grova C,  Kobayashi E
Link:https://www.ncbi.nlm.nih.gov/pubmed/25609211?dopt=Abstract
Category:Brain Topogr
PMID:25609211
Dept Affiliation: PERFORM
1 Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, 3801 University Street, Room 786, Montreal, QC, H3A 2B4, Canada. marcel.heers@gmail.com.
2 Epilepsy Center, University Medical Center Freiburg, Freiburg, Germany. marcel.heers@gmail.com.
3 Multimodal Functional Imaging Laboratory, Biomedical Engineering Department, McGill University, Montreal, Canada.
4 Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, 3801 University Street, Room 786, Montreal, QC, H3A 2B4, Canada.
5 Physnum-Team, Centre de Recherches Mathématiques, Montreal, Canada.
6 Physics Department and PERFORM Centre, Concordia University, Montreal, Canada.

Description:

Localization Accuracy of Distributed Inverse Solutions for Electric and Magnetic Source Imaging of Interictal Epileptic Discharges in Patients with Focal Epilepsy.

Brain Topogr. 2016 Jan;29(1):162-81

Authors: Heers M, Chowdhury RA, Hedrich T, Dubeau F, Hall JA, Lina JM, Grova C, Kobayashi E

Abstract

Distributed inverse solutions aim to realistically reconstruct the origin of interictal epileptic discharges (IEDs) from noninvasively recorded electroencephalography (EEG) and magnetoencephalography (MEG) signals. Our aim was to compare the performance of different distributed inverse solutions in localizing IEDs: coherent maximum entropy on the mean (cMEM), hierarchical Bayesian implementations of independent identically distributed sources (IID, minimum norm prior) and spatially coherent sources (COH, spatial smoothness prior). Source maxima (i.e., the vertex with the maximum source amplitude) of IEDs in 14 EEG and 19 MEG studies from 15 patients with focal epilepsy were analyzed. We visually compared their concordance with intracranial EEG (iEEG) based on 17 cortical regions of interest and their spatial dispersion around source maxima. Magnetic source imaging (MSI) maxima from cMEM were most often confirmed by iEEG (cMEM: 14/19, COH: 9/19, IID: 8/19 studies). COH electric source imaging (ESI) maxima co-localized best with iEEG (cMEM: 8/14, COH: 11/14, IID: 10/14 studies). In addition, cMEM was less spatially spread than COH and IID for ESI and MSI (p < 0.001 Bonferroni-corrected post hoc t test). Highest positive predictive values for cortical regions with IEDs in iEEG could be obtained with cMEM for MSI and with COH for ESI. Additional realistic EEG/MEG simulations confirmed our findings. Accurate spatially extended sources, as found in cMEM (ESI and MSI) and COH (ESI) are desirable for source imaging of IEDs because this might influence surgical decision. Our simulations suggest that COH and IID overestimate the spatial extent of the generators compared to cMEM.

PMID: 25609211 [PubMed - indexed for MEDLINE]