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Neural substrates of appetitive and aversive prediction error.

Author(s): Iordanova MD, Yau JO, McDannald MA, Corbit LH

Prediction error, defined by the discrepancy between real and expected outcomes, lies at the core of associative learning. Behavioural investigations have provided evidence that prediction error up- and down-regulates associative relationships, and allocate...

Article GUID: 33453307
Title:Neural substrates of appetitive and aversive prediction error.
Authors:Iordanova MD,  Yau JO,  McDannald MA,  Corbit LH
Link:https://www.ncbi.nlm.nih.gov/pubmed/33453307
DOI:10.1016/j.neubiorev.2020.10.029
Category:Neurosci Biobehav Rev
PMID:33453307
Dept Affiliation: CSBN
1 Department of Psychology/Centre for Studies in Behavioral Neurobiology, Concordia University, 7141 Sherbrooke St, Montreal, QC, H4B 1R6, Canada. Electronic address: mihaela.iordanova@concordia.ca.
2 School of Psychology, The University of New South Wales, UNSW Sydney, NSW, 2052, Australia. Electronic address: joanna.yau@unsw.edu.au.
3 Department of Psychology & Neuroscience, Boston College, 140 Commonwealth Avenue, 514 McGuinn Hall, Chestnut Hill, MA, 02467, USA. Electronic address: michael.mcdannald@bc.edu.
4 Departments of Psychology and Cell and Systems Biology, University of Toronto, 100 St. George Street, Toronto, ON, M5S 3G3, Canada. Electronic address: laura.corbit@utoronto.ca.

Description:

Neural substrates of appetitive and aversive prediction error.

Neurosci Biobehav Rev. 2021 Jan 13; :

Authors: Iordanova MD, Yau JO, McDannald MA, Corbit LH

Abstract

Prediction error, defined by the discrepancy between real and expected outcomes, lies at the core of associative learning. Behavioural investigations have provided evidence that prediction error up- and down-regulates associative relationships, and allocates attention to stimuli to enable learning. These behavioural advances have recently been followed by investigations into the neurobiological substrates of prediction error. In the present paper, we review neuroscience data obtained using causal and recording neural methods from a variety of key behavioural designs. We explore the neurobiology of both appetitive (reward) and aversive (fear) prediction error with a focus on the mesolimbic dopamine system, the amygdala, ventrolateral periaqueductal gray, hippocampus, cortex and locus coeruleus noradrenaline. New questions and avenues for research are considered.

PMID: 33453307 [PubMed - as supplied by publisher]