Keyword search (3,619 papers available)


Beyond sleepy: structural and functional changes of the default-mode network in idiopathic hypersomnia.

Author(s): Pomares FB, Boucetta S, Lachapelle F, Steffener J, Montplaisir J, Cha J, Kim H, Dang-Vu TT

Sleep. 2019 Jul 22;: Authors: Pomares FB, Boucetta S, Lachapelle F, Steffener J, Montplaisir J, Cha J, Kim H, Dang-Vu TT

Article GUID: 31328786
Brain perfusion during rapid-eye-movement sleep successfully identifies amnestic mild cognitive impairment.

Author(s): Brayet P, Petit D, Baril AA, Gosselin N, Gagnon JF, Soucy JP, Gauthier S, Kergoat MJ, Carrier J, Rouleau I, Montplaisir J

Sleep Med. 2017 Jun;34:134-140 Authors: Brayet P, Petit D, Baril AA, Gosselin N, Gagnon JF, Soucy JP, Gauthier S, Kergoat MJ, Carrier J, Rouleau I, Montplaisir J

Article GUID: 28522082
Brain cholinergic alterations in idiopathic REM sleep behaviour disorder: a PET imaging study with 18F-FEOBV.

Author(s): Bedard MA, Aghourian M, Legault-Denis C, Postuma RB, Soucy JP, Gagnon JF, Pelletier A, Montplaisir J

Sleep Med. 2019 Jan 06;58:35-41 Authors: Bedard MA, Aghourian M, Legault-Denis C, Postuma RB, Soucy JP, Gagnon JF, Pelletier A, Montplaisir J

Article GUID: 31078078
Sleep deprivation impairs inhibitory control during wakefulness in adult sleepwalkers.

Author(s): Labelle MA, Dang-Vu TT, Petit D, Desautels A, Montplaisir J, Zadra A

Sleep deprivation impairs inhibitory control during wakefulness in adult sleepwalkers.

J Sleep Res. 2015 Dec;24(6):658-65

Authors: Labelle MA, Dang-Vu TT, Petit D, Desautels A, Montplaisir J, Zadra A

Abstract

Sleepwalkers...

Article GUID: 26087833
Altered Regional Cerebral Blood Flow in Idiopathic Hypersomnia.

Author(s): Boucetta S, Montplaisir J, Zadra A, Lachapelle F, Soucy JP, Gravel P, Dang-Vu TT

Sleep. 2017 10 01;40(10): Authors: Boucetta S, Montplaisir J, Zadra A, Lachapelle F, Soucy JP, Gravel P, Dang-Vu TT

Article GUID: 28958044
Altered brain perfusion patterns in wakefulness and slow-wave sleep in sleepwalkers.

Author(s): Desjardins MÈ, Baril AA, Soucy JP, Dang-Vu TT, Desautels A, Petit D, Montplaisir J, Zadra A

Sleep. 2018 05 01;41(5): Authors: Desjardins MÈ, Baril AA, Soucy JP, Dang-Vu TT, Desautels A, Petit D, Montplaisir J, Zadra A

Article GUID: 29514303
Title:Brain perfusion during rapid-eye-movement sleep successfully identifies amnestic mild cognitive impairment.
Authors:Brayet P,  Petit D,  Baril AA,  Gosselin N,  Gagnon JF,  Soucy JP,  Gauthier S,  Kergoat MJ,  Carrier J,  Rouleau I,  Montplaisir J
Link:https://www.ncbi.nlm.nih.gov/pubmed/28522082?dopt=Abstract
DOI:10.1016/j.sleep.2017.01.025
Category:Sleep Med
PMID:28522082
Dept Affiliation: PERFORM
1 Department of Psychology, Université du Québec à Montréal, Montréal, Canada; Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Coeur de Montréal, Montréal, Canada.
2 Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Coeur de Montréal, Montréal, Canada.
3 Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Coeur de Montréal, Montréal, Canada; Faculty of Medicine, Université de Montréal, Montréal, Canada.
4 Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Coeur de Montréal, Montréal, Canada; Department of Psychology, Université de Montréal, Montréal, Canada.
5 Montreal Neurological Institute, McGill University, Montréal, Canada; PERFORM Centre, Concordia University, Montréal, Canada.
6 McGill University Research Centre for Studies in Aging, Douglas Hospital, Verdun, Canada.
7 Faculty of Medicine, Université de Montréal, Montréal, Canada; Research Center, Institut universitaire de gériatrie de Montréal, Montreal, Canada.
8 Department of Psychology, Université du Québec à Montréal, Montréal, Canada; Neurology Service, Hôpital Notre-Dame du CHUM, Montréal, Canada.
9 Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Coeur de Montréal, Montréal, Canada; Faculty of Medicine, Université de Montréal, Montréal, Canada. Electronic address: jy.montplaisir@umontreal.ca.

Description:

Brain perfusion during rapid-eye-movement sleep successfully identifies amnestic mild cognitive impairment.

Sleep Med. 2017 Jun;34:134-140

Authors: Brayet P, Petit D, Baril AA, Gosselin N, Gagnon JF, Soucy JP, Gauthier S, Kergoat MJ, Carrier J, Rouleau I, Montplaisir J

Abstract

INTRODUCTION: Prodromal markers of Alzheimer's disease (AD) have been derived from wakefulness. However, brain perfusion during rapid-eye movement (REM) sleep could be a sensitive marker of amnestic mild cognitive impairment (aMCI), as activation of REM sleep relies more on the cholinergic system.

METHODS: Eight subjects with aMCI, and 16 controls, underwent two single-photon emission computed tomography (SPECT) scans with tracer injected during REM sleep then wakefulness.

RESULTS: Perfusion in the anterior cingulate cortex was significantly decreased in aMCI cases compared to controls for both conditions. That defect was much larger and more severe in REM sleep (1795 voxels) compared to wakefulness (398 voxels), and extended to the middle cingulate cortex and the olfactory cortex. Hypoperfusion in the anterior cingulate cortex during REM sleep allowed better classification than hypoperfusion found in wakefulness (93.8 vs 81.3%).

CONCLUSION: REM sleep imaging is a valuable tool with which to identify individuals at risk of developing AD.

PMID: 28522082 [PubMed - indexed for MEDLINE]