Keyword search (3,448 papers available)


Near native-like stress pattern perception in English-French bilinguals as indexed by the mismatch negativity.

Author(s): Gilbert AC, Honda CT, Phillips NA, Baum SR

We examined lexical stress processing in English-French bilinguals. Auditory mismatch negativity (MMN) responses were recorded in response to English and French pseudowords, whose primary stress occurred either on a language-consistent "usual" or language-i...

Article GUID: 33333337
Clinical judgement is paramount when performing cognitive screening during COVID-19.

Author(s): Phillips NA, Andrews M, Chertkow H, Pichora-Fuller MK, Rockwood K, Wittich W

J Am Geriatr Soc. 2020 May 12;: Authors: Phillips NA, Andrews M, Chertkow H, Pichora-Fuller MK, Rockwood K, Wittich W PMID: 32396983 [PubMed - as supplied by publisher]

Article GUID: 32396983
Special issues on using the MoCA for remote assessment during COVID-19 2.

Author(s): Phillips NA, Chertkow H, Pichora-Fuller MK, Wittich W

J Am Geriatr Soc. 2020 Apr 06;: Authors: Phillips NA, Chertkow H, Pichora-Fuller MK, Wittich W PMID: 32253754 [PubMed - as supplied by publisher]

Article GUID: 32253754
Detection of vision and /or hearing loss using the interRAI Community Health Assessment aligns well with common behavioral vision/hearing measurements.

Author(s): Urqueta Alfaro A, Guthrie DM, Phillips NA, Pichora-Fuller MK, Mick P, McGraw C, Wittich W

PLoS One. 2019;14(10):e0223123 Authors: Urqueta Alfaro A, Guthrie DM, Phillips NA, Pichora-Fuller MK, Mick P, McGraw C, Wittich W

Article GUID: 31581243
The Comprehensive Assessment of Neurodegeneration and Dementia: Canadian Cohort Study.

Author(s): Chertkow H, Borrie M, Whitehead V, Black SE, Feldman HH, Gauthier S, Hogan DB, Masellis M, McGilton K, Rockwood K, Tierney MC, Andrew M, Hsi...

Can J Neurol Sci. 2019 Jul 16;:1-13 Authors: Chertkow H, Borrie M, Whitehead V, Black SE, Feldman HH, Gauthier S, Hogan DB, Masellis M, McGilton K, Rockwood K, Tierney MC, Andrew M, Hsiung GR, Cam...

Article GUID: 31309917
Breaking the waves: age differences in electrical brain activity when reading text with distractors.

Author(s): Phillips NA, Lesperance D

Psychol Aging. 2003 Mar;18(1):126-39 Authors: Phillips NA, Lesperance D

Article GUID: 12641317
Functional and anatomical memory indices in patients with or at risk for Alzheimer's disease.

Author(s): Phillips NA, Chertkow H, Leblanc MM, Pim H, Murtha S

J Int Neuropsychol Soc. 2004 Mar;10(2):200-10 Authors: Phillips NA, Chertkow H, Leblanc MM, Pim H, Murtha S

Article GUID: 15012840
Behavioural and electrophysiological measures of task switching during single and mixed-task conditions.

Author(s): Goffaux P, Phillips NA, Sinai M, Pushkar D

Biol Psychol. 2006 Jun;72(3):278-90 Authors: Goffaux P, Phillips NA, Sinai M, Pushkar D

Article GUID: 16413655
Neurophysiological measures of task-set switching: effects of working memory and aging.

Author(s): Goffaux P, Phillips NA, Sinai M, Pushkar D

J Gerontol B Psychol Sci Soc Sci. 2008 Mar;63(2):P57-66 Authors: Goffaux P, Phillips NA, Sinai M, Pushkar D

Article GUID: 18441266
Microstructural white matter changes mediate age-related cognitive decline on the Montreal Cognitive Assessment (MoCA).

Author(s): Jolly TA, Cooper PS, Badwi SA, Phillips NA, Rennie JL, Levi CR, Drysdale KA, Parsons MW, Michie PT, Karayanidis F

Psychophysiology. 2016 Feb;53(2):258-67 Authors: Jolly TA, Cooper PS, Badwi SA, Phillips NA, Rennie JL, Levi CR, Drysdale KA, Parsons MW, Michie PT, Karayanidis F

Article GUID: 26511789
Early diagnosis of mild cognitive impairment and Alzheimer's with event-related potentials and event-related desynchronization in N-back working memory tasks.

Author(s): Fraga FJ, Mamani GQ, Johns E, Tavares G, Falk TH, Phillips NA

Comput Methods Programs Biomed. 2018 Oct;164:1-13 Authors: Fraga FJ, Mamani GQ, Johns E, Tavares G, Falk TH, Phillips NA

Article GUID: 30195417
Title:Microstructural white matter changes mediate age-related cognitive decline on the Montreal Cognitive Assessment (MoCA).
Authors:Jolly TA,  Cooper PS,  Badwi SA,  Phillips NA,  Rennie JL,  Levi CR,  Drysdale KA,  Parsons MW,  Michie PT,  Karayanidis F
Link:https://www.ncbi.nlm.nih.gov/pubmed/26511789?dopt=Abstract
Category:Psychophysiology
PMID:26511789
Dept Affiliation: PSYCHOLOGY
1 Functional Neuroimaging Laboratory, School of Psychology, Faculty of Science & IT, University of Newcastle, Newcastle, Australia.
2 Centre for Brain and Mental Health Research, University of Newcastle, Newcastle, Australia.
3 Hunter Medical Research Institute, Newcastle, Australia.
4 Department of Psychology, Kulliyyah of IRKHS, International Islamic University Malaysia, Kuala Lumpur, Malaysia.
5 Centre for Research in Human Development, Department of Psychology, Concordia University, Montreal, Quebec, Canada.
6 Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada.
7 School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, Newcastle, Australia.

Description:

Microstructural white matter changes mediate age-related cognitive decline on the Montreal Cognitive Assessment (MoCA).

Psychophysiology. 2016 Feb;53(2):258-67

Authors: Jolly TA, Cooper PS, Badwi SA, Phillips NA, Rennie JL, Levi CR, Drysdale KA, Parsons MW, Michie PT, Karayanidis F

Abstract

Although the relationship between aging and cognitive decline is well established, there is substantial individual variability in the degree of cognitive decline in older adults. The present study investigates whether variability in cognitive performance in community-dwelling older adults is related to the presence of whole brain or tract-specific changes in white matter microstructure. Specifically, we examine whether age-related decline in performance on the Montreal Cognitive Assessment (MoCA), a cognitive screening tool, is mediated by the white matter microstructural decline. We also examine if this relationship is driven by the presence of cardiovascular risk factors or variability in cerebral arterial pulsatility, an index of cardiovascular risk. Sixty-nine participants (aged 43-87) completed behavioral and MRI testing including T1 structural, T2-weighted FLAIR, and diffusion-weighted imaging (DWI) sequences. Measures of white matter microstructure were calculated using diffusion tensor imaging analyses on the DWI sequence. Multiple linear regression revealed that MoCA scores were predicted by radial diffusivity (RaD) of white matter beyond age or other cerebral measures. While increasing age and arterial pulsatility were associated with increasing RaD, these factors did not mediate the relationship between total white matter RaD and MoCA. Further, the relationship between MoCA and RaD was specific to participants who reported at least one cardiovascular risk factor. These findings highlight the importance of cardiovascular risk factors in the presentation of cognitive decline in old age. Further work is needed to establish whether medical or lifestyle management of these risk factors can prevent or reverse cognitive decline in old age.

PMID: 26511789 [PubMed - indexed for MEDLINE]