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Efficient genome editing using tRNA promoter-driven CRISPR/Cas9 gRNA in Aspergillus niger.

Author(s): Song L, Ouedraogo JP, Kolbusz M, Nguyen TTM, Tsang A

PLoS One. 2018;13(8):e0202868 Authors: Song L, Ouedraogo JP, Kolbusz M, Nguyen TTM, Tsang A

Article GUID: 30142205

Phylogenetic Analysis of Protein Family.

Author(s): Song L, Wu S, Tsang A

Phylogenetic Analysis of Protein Family.

Methods Mol Biol. 2018;1775:267-275

Authors: Song L, Wu S, Tsang A

Abstract
With the number of sequenced genomes increasing rapidly, it is impractical to perform functional and stru...

Article GUID: 29876824


Title:Phylogenetic Analysis of Protein Family.
Authors:Song LWu STsang A
Link:www.ncbi.nlm.nih.gov/pubmed/29876824?dopt=Abstract
Category:Methods Mol Biol
PMID:29876824
Dept Affiliation: GENOMICS
1 Centre for Structural and Functional Genomics, Concordia University, 7141 Sherbrooke Street West, Montreal, H4B 1R6, Quebec, Canada. letian.song@concordia.ca.
2 Centre for Structural and Functional Genomics, Concordia University, 7141 Sherbrooke Street West, Montreal, H4B 1R6, Quebec, Canada.
3 Centre for Structural and Functional Genomics, Concordia University, Montreal, QC, Canada.

Description:

Phylogenetic Analysis of Protein Family.



Methods Mol Biol. 2018;1775:267-275



Authors: Song L, Wu S, Tsang A



Abstract

With the number of sequenced genomes increasing rapidly, it is impractical to perform functional and structural analyses on all individual proteins. Phylogenetic analysis employs a combination of molecular and statistical approaches to infer or estimate relationships among individuals. It provides a credible method to explore the relationship between sequence similarity and function of proteins belonging to the same family. This chapter describes a standardized framework of phylogenetic analysis to study large protein families. Bioinformatic approaches and online tools used in phylogenetic analyses are presented.



PMID: 29876824 [PubMed - indexed for MEDLINE]