Keyword search (3,619 papers available)


Pretreatment motivation and therapy outcomes in eating disorders: A systematic review and meta-analysis.

Author(s): Sansfaçon J, Booij L, Gauvin L, Fletcher É, Islam F, Israël M, Steiger H

OBJECTIVE: Identifying modifiable predictors of outcomes following treatment for eating disorders may help to tailor interventions to patients' individual needs, improve treatment efficacy, and develop new interventions. The goal of this meta-analysis w...

Article GUID: 32954512
Applying epigenetic science to the understanding of eating disorders: a promising paradigm for research and practice.

Author(s): Booij L, Steiger H

Curr Opin Psychiatry. 2020 Jun 22;: Authors: Booij L, Steiger H

Article GUID: 32576735
Eating Disorders, Heredity and Environmental Activation: Getting Epigenetic Concepts into Practice.

Author(s): Steiger H, Booij L

J Clin Med. 2020 May 03;9(5): Authors: Steiger H, Booij L

Article GUID: 32375223
Late and Instable Sleep Phasing is Associated With Irregular Eating Patterns in Eating Disorders.

Author(s): Linnaranta O, Bourguignon C, Crescenzi O, Sibthorpe D, Buyukkurt A, Steiger H, Storch KF

Ann Behav Med. 2020 Mar 25;: Authors: Linnaranta O, Bourguignon C, Crescenzi O, Sibthorpe D, Buyukkurt A, Steiger H, Storch KF

Article GUID: 32211873
Methylation of the OXTR gene in women with anorexia nervosa: Relationship to social behavior.

Author(s): Thaler L, Brassard S, Booij L, Kahan E, McGregor K, Labbe A, Israel M, Steiger H

Eur Eat Disord Rev. 2019 Dec 10;: Authors: Thaler L, Brassard S, Booij L, Kahan E, McGregor K, Labbe A, Israel M, Steiger H

Article GUID: 31823473
A longitudinal, epigenome-wide study of DNA methylation in anorexia nervosa: results in actively ill, partially weight-restored, long-term remitted and non-eating-disordered women

Author(s): Steiger H, Booij L, Kahan `, McGregor K, Thaler L, Fletcher E, Labbe A, Joober R, Israël M, Szyf M, Agellon LB, Gauvin L, St-Hilaire A, Rossi E

J Psychiatry Neurosci. 2019 05 01;44(3):205-213 Authors: Steiger H, Booij L, Kahan `, McGregor K, Thaler L, Fletcher E, Labbe A, Joober R, Israël M, Szyf M, Agellon LB, Gauvin L, St-Hilaire A, Rossi E

Article GUID: 30693739
Title:Applying epigenetic science to the understanding of eating disorders: a promising paradigm for research and practice.
Authors:Booij L,  Steiger H
Link:https://www.ncbi.nlm.nih.gov/pubmed/32576735?dopt=Abstract
DOI:10.1097/YCO.0000000000000632
Category:Curr Opin Psychiatry
PMID:32576735
Dept Affiliation: PSYCHOLOGY
1 Department of Psychology, Concordia University.
2 CHU Sainte-Justine Hospital.
3 Department of Psychiatry, McGill University.
4 Eating Disorders Continuum, Douglas Institute.
5 Research Centre, Douglas University Institute, Montreal, Quebec, Canada.

Description:

Applying epigenetic science to the understanding of eating disorders: a promising paradigm for research and practice.

Curr Opin Psychiatry. 2020 Jun 22;:

Authors: Booij L, Steiger H

Abstract

PURPOSE OF REVIEW: Studies indicate that environmental factors, acting at various moments throughout the life cycle, can result in epigenetically mediated alterations in gene expression. In this article, we review recent findings on the role of epigenetic factors in eating disorders, address methodological issues that need to be considered when interpreting research findings, and comment on possible clinical applications.

RECENT FINDINGS: Evidence suggests that eating disorders implicate alterations of methylation in genes involved in the mental status, metabolism, anthropometric features and immunity. Furthermore, some research in individuals with anorexia nervosa suggests the presence of reversible, malnutrition-induced epigenetic alterations that 'reset' as patients recover.

SUMMARY: Epigenetic studies in the eating disorders corroborate the idea that eating disorder cause is multifactorial, and identify markers that could help inform our understanding of illness staging and subtyping that may explain the commonly progressive course of these disorders, and that may provide insights towards the development of novel interventions. Already, there is evidence to suggest that, in people with eating disorders, epigenetically informed interventions help reduce stigma and shame, and increase self-acceptance and hopes of recovery. Although findings are intriguing, further research is required as, to date, studies apply modest sample sizes and disparate methodologies.

PMID: 32576735 [PubMed - as supplied by publisher]