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Inactograms and objective sleep measures as means to capture subjective sleep problems in patients with a bipolar disorder.

Author(s): Lavin-Gonzalez P, Bourguignon C, Crescenzi O, Beaulieu S, Storch KF, Linnaranta O

Bipolar Disord. 2020 Mar 30;: Authors: Lavin-Gonzalez P, Bourguignon C, Crescenzi O, Beaulieu S, Storch KF, Linnaranta O

Article GUID: 32232937
Late and Instable Sleep Phasing is Associated With Irregular Eating Patterns in Eating Disorders.

Author(s): Linnaranta O, Bourguignon C, Crescenzi O, Sibthorpe D, Buyukkurt A, Steiger H, Storch KF

Ann Behav Med. 2020 Mar 25;: Authors: Linnaranta O, Bourguignon C, Crescenzi O, Sibthorpe D, Buyukkurt A, Steiger H, Storch KF

Article GUID: 32211873
The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4.

Author(s): Pathak SS, Liu D, Li T, de Zavalia N, Zhu L, Li J, Karthikeyan R, Alain T, Liu AC, Storch KF, Kaufman RJ, Jin VX, Amir S, Sonenberg N, Cao R

Neuron. 2019 Aug 26;: Authors: Pathak SS, Liu D, Li T, de Zavalia N, Zhu L, Li J, Karthikeyan R, Alain T, Liu AC, Storch KF, Kaufman RJ, Jin VX, Amir S, Sonenberg N, Cao R

Article GUID: 31522764
Light-regulated translational control of circadian behavior by eIF4E phosphorylation.

Author(s): Cao R, Gkogkas CG, de Zavalia N, Blum ID, Yanagiya A, Tsukumo Y, Xu H, Lee C, Storch KF, Liu AC, Amir S, Sonenberg N

Nat Neurosci. 2015 Jun;18(6):855-62 Authors: Cao R, Gkogkas CG, de Zavalia N, Blum ID, Yanagiya A, Tsukumo Y, Xu H, Lee C, Storch KF, Liu AC, Amir S, Sonenberg N

Article GUID: 25915475
Title:Inactograms and objective sleep measures as means to capture subjective sleep problems in patients with a bipolar disorder.
Authors:Lavin-Gonzalez P,  Bourguignon C,  Crescenzi O,  Beaulieu S,  Storch KF,  Linnaranta O
Link:https://www.ncbi.nlm.nih.gov/pubmed/32232937?dopt=Abstract
DOI:10.1111/bdi.12903
Category:Bipolar Disord
PMID:32232937
Dept Affiliation: PSYCHOLOGY
1 Department of Psychiatry, McGill University, Montreal, Québec, Canada.
2 Douglas Group for Sleep and Biological Rhythms, Douglas Mental Health University Institute, Montreal, Québec, Canada.
3 Integrated Program in Neuroscience, McGill University, Montreal, Québec, Canada.
4 Department of Psychology, Concordia University, Montreal, Québec, Canada.

Description:

Inactograms and objective sleep measures as means to capture subjective sleep problems in patients with a bipolar disorder.

Bipolar Disord. 2020 Mar 30;:

Authors: Lavin-Gonzalez P, Bourguignon C, Crescenzi O, Beaulieu S, Storch KF, Linnaranta O

Abstract

BACKGROUND: Sleep problems are common in bipolar disorders (BDs). To objectively characterize these problems in BDs, further methodological development is needed to capture subjective insomnia.

AIM: To test psychometric properties of the Athens Insomnia Scale (AIS), and associations with actigraphy-derived measures, applying modifications in actigraphy data processing to capture features of perturbed sleep in patients with a BD.

METHODS: Seventy-four patients completed the AIS and the Quick Inventory of Depressive Symptomatology, self-report (QIDS-SR-16). Locomotor activity was continuously recorded by wrist-actigraphy for =10 consecutive days. We computed the sleep onset/offset, the center of daily inactivity (CenDI), as a proxy for chronotype, and the degree of consolidation of daily inactivity (ConDI), as a proxy for sleep-wake rhythm strength.

RESULTS: AIS showed good psychometric properties (Cronbach's alpha=0.84; test-retest correlation=0.84, p<.001). Subjective sleep problems correlated moderately with a later sleep phase (CenDI with AIS rho=0.34, p=.003), lower consolidation (ConDI with AIS rho=-0.22, p=.05; with QIDS-SR-16 rho=-0.27, p=.019), later timing of sleep offset (with AIS rho=0.49, p= =.001, with QIDS-SR-16 rho=0.36, p=.002), and longer total sleep (with AIS rho=0.29, p=.012, with QIDS-SR-16 rho=0.41, p==.001). While AIS was psychometrically more solid, correlations with objective sleep were more consistent across time for QIDS-SR-16.

CONCLUSIONS: AIS and QIDS-SR-16 are suitable for clinical screening of sleep problems among patients with a BD. Subjective insomnia associated with objective measures. For clinical and research purposes, actigraphy and data visualization on inactograms are useful for accurate longitudinal characterization of sleep patterns.

PMID: 32232937 [PubMed - as supplied by publisher]