Keyword search (3,619 papers available)


EQ-5D-5L and SF-6Dv2 utility scores in people living with chronic low back pain: a survey from Quebec.

Author(s): Poder TG, Wang L, Carrier N

OBJECTIVE: To describe how chronic low back pain (CLBP) impacts on utility scores and which patients' characteristics most affect these scores in the province of Quebec. SETTINGS: Province of Quebec, Canada. PARTICIPANTS: 569 adult patients with CLBP. M...

Article GUID: 32933957
Life after breast cancer: moving on, sitting down or standing still? A prospective study of Canadian breast cancer survivors.

Author(s): Sabiston CM, Wrosch C, Fong AJ, Brunet J, Gaudreau P, O'Loughlin J, Meterissian S

BMJ Open. 2018 07 28;8(7):e021770 Authors: Sabiston CM, Wrosch C, Fong AJ, Brunet J, Gaudreau P, O'Loughlin J, Meterissian S

Article GUID: 30056387
Adverse childhood experiences (ACEs) and cardiovascular development from childhood to early adulthood: study protocol of the Niagara Longitudinal Heart Study.

Author(s): Wade TJ, O'Leary DD, Dempster KS, MacNeil AJ, Molnar DS, McGrath J, Cairney J

BMJ Open. 2019 Jul 16;9(7):e030339 Authors: Wade TJ, O'Leary DD, Dempster KS, MacNeil AJ, Molnar DS, McGrath J, Cairney J

Article GUID: 31315878
Diagnostic accuracy of the Depression subscale of the Hospital Anxiety and Depression Scale (HADS-D) for detecting major depression: protocol for a systematic review and individual patient data meta-analyses.

Author(s): Thombs BD, Benedetti A, Kloda LA, Levis B, Azar M, Riehm KE, Saadat N, Cuijpers P, Gilbody S, Ioannidis JP, McMillan D, Patten SB, Shrier I,...

BMJ Open. 2016 Apr 13;6(4):e011913 Authors: Thombs BD, Benedetti A, Kloda LA, Levis B, Azar M, Riehm KE, Saadat N, Cuijpers P, Gilbody S, Ioannidis JP, McMillan D, Patten SB, Shrier I, Steele RJ, ...

Article GUID: 27075844
Title:Adverse childhood experiences (ACEs) and cardiovascular development from childhood to early adulthood: study protocol of the Niagara Longitudinal Heart Study.
Authors:Wade TJ,  O'Leary DD,  Dempster KS,  MacNeil AJ,  Molnar DS,  McGrath J,  Cairney J
Link:https://www.ncbi.nlm.nih.gov/pubmed/31315878?dopt=Abstract
DOI:10.1136/bmjopen-2019-030339
Category:BMJ Open
PMID:31315878
Dept Affiliation: PSYCHOLOGY
1 Health Sciences, Brock University, St. Catharines, Ontario, Canada.
2 Brock-NIagara Centre for Health and Well-Being, Brock University, St. Catharines, Ontario, Canada.
3 Child and Youth Studies, Brock University, St. Catharines, Ontario, Canada.
4 Department of Psychology, Concordia University, Montreal, Quebec, Canada.
5 Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, Ontario, Canada.

Description:

Adverse childhood experiences (ACEs) and cardiovascular development from childhood to early adulthood: study protocol of the Niagara Longitudinal Heart Study.

BMJ Open. 2019 Jul 16;9(7):e030339

Authors: Wade TJ, O'Leary DD, Dempster KS, MacNeil AJ, Molnar DS, McGrath J, Cairney J

Abstract

INTRODUCTION: Recent reviews have found substantial links between a toxic childhood environment including child abuse and severe household dysfunction and adult cardiovascular disease (CVD). Collectively referred to as adverse childhood experiences (ACEs), this toxic environment is prevalent among children, with recent Canadian estimates of child abuse at 27%-32%, and severe household dysfunction at 49%. Based on these prevalence rates, the potential effect of ACEs on CVD is more significant than previously thought. Yet, how ACEs amplify the risk for later CVD remains unclear. Lifestyle risk factors only partially account for this connection, instead directing attention to the interaction between psychosocial factors and physiological mechanisms such as inflammation. The Niagara Longitudinal Heart Study (NLHS) examines how ACEs influence cardiovascular health (CVH) from childhood to early adulthood. Integrating the stress process and biological embedding models, this study examines how psychosocial and physiological factors in addition to lifestyle factors explain the relationship between ACEs and CVH.

METHODS: This follow-up study combines three baseline studies from 2007 to 2012 that collected CVH measures including child blood pressure, heart rate, left ventricular structure and function, arterial stiffness indices and baroreflex sensitivity on 564 children. Baseline data also include anthropometric, biological, lifestyle, behavioural, and psychosocial measures that varied across primary studies. Now over 18 years of age, we will recruit and retest as many participants from the baseline studies as possible collecting data on ACEs, CVH, anthropometric, lifestyle and psychosocial measures as well as blood, saliva and hair for physiological biostress markers.

ETHICS AND DISSEMINATION: Ethics approval has been received for the NLHS follow-up. Written consent to participate in the follow-up study is obtained from each participant. Results testing all proposed hypotheses will be submitted for publication in peer-reviewed journals.

PMID: 31315878 [PubMed - in process]