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Treatment for hypoactive sexual desire.

Author(s): Pfaus JG

Cell. 2015 Oct 22;163(3):533 Authors: Pfaus JG

Article GUID: 26496594
Title:Treatment for hypoactive sexual desire.
Authors:Pfaus JG
Link:https://www.ncbi.nlm.nih.gov/pubmed/26496594?dopt=Abstract
Category:Cell
PMID:26496594
Dept Affiliation: PSYCHOLOGY
1 Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montréal, QC H4B 1R6, Canada. Electronic address: jim.pfaus@concordia.ca.

Description:

Treatment for hypoactive sexual desire.

Cell. 2015 Oct 22;163(3):533

Authors: Pfaus JG

Abstract

Flibanserin acts at cortical, limbic, hypothalamic, and brainstem nuclei to inhibit serotonin release by binding to 5-HT1A autoreceptors and block postsynaptic action of serotonin at 5-HT2A receptors. This gradually disinhibits the turnover of other monoamines like dopamine and noradrenaline that are critical for sexual desire.

PMID: 26496594 [PubMed - indexed for MEDLINE]