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Different methods of fear reduction are supported by distinct cortical substrates.

Author(s): Lay BP, Pitaru AA, Boulianne N, Esber GR, Iordanova MD

Elife. 2020 Jun 26;9: Authors: Lay BP, Pitaru AA, Boulianne N, Esber GR, Iordanova MD

Article GUID: 32589138
Network-wide reorganization of procedural memory during NREM sleep revealed by fMRI.

Author(s): Vahdat S, Fogel S, Benali H, Doyon J

Network-wide reorganization of procedural memory during NREM sleep revealed by fMRI.
Elife. 2017 09 11;6:
Authors: Vahdat S, Fogel S, Benali H, Doyon J
Abstract
Sleep is necessary for the optimal consolidation of newly acquired procedural me...

Article GUID: 28892464
Metacontrol of decision-making strategies in human aging.

Author(s): Bolenz F, Kool W, Reiter AM, Eppinger B

Elife. 2019 Aug 09;8: Authors: Bolenz F, Kool W, Reiter AM, Eppinger B

Article GUID: 31397670
Consolidation alters motor sequence-specific distributed representations.

Author(s): Pinsard B, Boutin A, Gabitov E, Lungu O, Benali H, Doyon J

Elife. 2019 Mar 18;8: Authors: Pinsard B, Boutin A, Gabitov E, Lungu O, Benali H, Doyon J

Article GUID: 30882348
Title:Consolidation alters motor sequence-specific distributed representations.
Authors:Pinsard B,  Boutin A,  Gabitov E,  Lungu O,  Benali H,  Doyon J
Link:https://www.ncbi.nlm.nih.gov/pubmed/30882348?dopt=Abstract
DOI:10.7554/eLife.39324
Category:Elife
PMID:30882348
Dept Affiliation: PERFORM
1 Laboratoire d'Imagerie Biomédicale, Sorbonne Université, CNRS, INSERM, Paris, France.
2 Functional Neuroimaging Unit, Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, Canada.
3 McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Canada.
4 PERFORM Centre, Concordia University, Montreal, Canada.
5 Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Canada.

Description:

Consolidation alters motor sequence-specific distributed representations.

Elife. 2019 Mar 18;8:

Authors: Pinsard B, Boutin A, Gabitov E, Lungu O, Benali H, Doyon J

Abstract

Functional magnetic resonance imaging (fMRI) studies investigating the acquisition of sequential motor skills in humans have revealed learning-related functional reorganizations of the cortico-striatal and cortico-cerebellar motor systems accompanied with an initial hippocampal contribution. Yet, the functional significance of these activity-level changes remains ambiguous as they convey the evolution of both sequence-specific knowledge and unspecific task ability. Moreover, these changes do not specifically assess the occurrence of learning-related plasticity. To address these issues, we investigated local circuits tuning to sequence-specific information using multivariate distances between patterns evoked by consolidated or newly acquired motor sequences production. The results reveal that representations in dorsolateral striatum, prefrontal and secondary motor cortices are greater when executing consolidated sequences than untrained ones. By contrast, sequence representations in the hippocampus and dorsomedial striatum becomes less engaged. Our findings show, for the first time in humans, that complementary sequence-specific motor representations evolve distinctively during critical phases of skill acquisition and consolidation.

PMID: 30882348 [PubMed - in process]