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Structural brain differences between monolingual and multilingual patients with mild cognitive impairment and Alzheimer disease: Evidence for cognitive reserve

Author(s): Hilary D Duncan

Two independent lines of research provide evidence that speaking more than one language may 1) contribute to increased grey matter in healthy younger and older adults and 2) delay cognitive symptoms in mild cognitive impairment (MCI) or Alzheimer disease (A...

Article GUID: 29287966
Title:Structural brain differences between monolingual and multilingual patients with mild cognitive impairment and Alzheimer disease: Evidence for cognitive reserve
Authors:Hilary D Duncan
Link:https://pubmed.ncbi.nlm.nih.gov/29287966/
DOI:10.1016/j.neuropsychologia.2017.12.036
Category:Neuropsychologia
PMID:29287966
Dept Affiliation: PSYCHOLOGY
1 Department of Psychology, Concordia University, Montréal, QC, Canada; Centre for Research in Human Development, Montréal, QC, Canada.
2 Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montréal, QC, Canada.
3 Department of Psychology, Concordia University, Montréal, QC, Canada; Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, QC, Canada.
4 Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montréal, QC, Canada; Department of Neurology and Neurosurgery, McGill University, Montréal, QC, Canada.
5 Department of Psychology, Concordia University, Montréal, QC, Canada; Centre for Research in Human Development, Montréal, QC, Canada; Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montréal, QC, Canada; Centre for Research on Brain, Language, and Music, Montréal, QC, Canada. Electronic address: natalie.phillips@concordia.ca.

Description:

Two independent lines of research provide evidence that speaking more than one language may 1) contribute to increased grey matter in healthy younger and older adults and 2) delay cognitive symptoms in mild cognitive impairment (MCI) or Alzheimer disease (AD). We examined cortical thickness and tissue density in monolingual and multilingual MCI and AD patients matched (within Diagnosis Groups) on demographic and cognitive variables. In medial temporal disease-related (DR) areas, we found higher...