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Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs.

Author(s): Laurent JM, Garge RK, Teufel AI, Wilke CO, Kachroo AH, Marcotte EM

PLoS Biol. 2020 May 18;18(5):e3000627 Authors: Laurent JM, Garge RK, Teufel AI, Wilke CO, Kachroo AH, Marcotte EM

Article GUID: 32421706
Inferring the distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii.

Author(s): Böndel KB, Kraemer SA, Samuels T, McClean D, Lachapelle J, Ness RW, Colegrave N, Keightley PD

PLoS Biol. 2019 Jun 26;17(6):e3000192 Authors: Böndel KB, Kraemer SA, Samuels T, McClean D, Lachapelle J, Ness RW, Colegrave N, Keightley PD

Article GUID: 31242179
Rhythm and time in the premotor cortex.

Author(s): Penhune VB, Zatorre RJ

PLoS Biol. 2019 Jun 03;17(6):e3000293 Authors: Penhune VB, Zatorre RJ

Article GUID: 31158227
Title:Rhythm and time in the premotor cortex.
Authors:Penhune VB,  Zatorre RJ
Link:https://www.ncbi.nlm.nih.gov/pubmed/31158227?dopt=Abstract
Category:PLoS Biol
PMID:31158227
Dept Affiliation: PSYCHOLOGY
1 Department of Psychology, Concordia University, Montreal, Quebec, Canada.
2 Laboratory for Brain, Music and Sound Research-BRAMS, Montreal, Quebec, Canada.
3 Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.

Description:

Rhythm and time in the premotor cortex.

PLoS Biol. 2019 Jun 03;17(6):e3000293

Authors: Penhune VB, Zatorre RJ

Abstract

Many animals can encode temporal intervals and use them to plan their actions, but only humans can flexibly extract a regular beat from complex patterns, such as musical rhythms. Beat-based timing is hypothesized to rely on the integration of sensory information with temporal information encoded in motor regions such as the medial premotor cortex (MPC), but how beat-based timing might be encoded in neuronal populations is mostly unknown. Gámez and colleagues show that the MPC encodes temporal information via a population code visible as circular trajectories in state space; these patterns may represent precursors to more-complex skills such as beat-based timing.

PMID: 31158227 [PubMed - as supplied by publisher]