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The acute effects of intranasal oxytocin on automatic and effortful attentional shifting to emotional faces.

Author(s): Ellenbogen MA, Linnen AM, Grumet R, Cardoso C, Joober R

Psychophysiology. 2012 Jan;49(1):128-37 Authors: Ellenbogen MA, Linnen AM, Grumet R, Cardoso C, Joober R

Article GUID: 22092248
Intranasal oxytocin attenuates the human acoustic startle response independent of emotional modulation.

Author(s): Ellenbogen MA, Linnen AM, Cardoso C, Joober R

Psychophysiology. 2014 Nov;51(11):1169-77 Authors: Ellenbogen MA, Linnen AM, Cardoso C, Joober R

Article GUID: 25082371
Microstructural white matter changes mediate age-related cognitive decline on the Montreal Cognitive Assessment (MoCA).

Author(s): Jolly TA, Cooper PS, Badwi SA, Phillips NA, Rennie JL, Levi CR, Drysdale KA, Parsons MW, Michie PT, Karayanidis F

Psychophysiology. 2016 Feb;53(2):258-67 Authors: Jolly TA, Cooper PS, Badwi SA, Phillips NA, Rennie JL, Levi CR, Drysdale KA, Parsons MW, Michie PT, Karayanidis F

Article GUID: 26511789
Title:Intranasal oxytocin attenuates the human acoustic startle response independent of emotional modulation.
Authors:Ellenbogen MA,  Linnen AM,  Cardoso C,  Joober R
Link:https://www.ncbi.nlm.nih.gov/pubmed/25082371?dopt=Abstract
Category:Psychophysiology
PMID:25082371
Dept Affiliation: CRDH
1 Centre for Research in Human Development, Concordia University, Montréal, Québec, Canada.

Description:

Intranasal oxytocin attenuates the human acoustic startle response independent of emotional modulation.

Psychophysiology. 2014 Nov;51(11):1169-77

Authors: Ellenbogen MA, Linnen AM, Cardoso C, Joober R

Abstract

Oxytocin promotes social affiliation in humans. However, the mechanisms underlying this phenomenon require further elucidation. The present study investigated the influence of intranasal oxytocin on basic emotional processing in men and women, using an emotion-modulated startle response paradigm. Eighty-four participants self-administered 24?IU of intranasal oxytocin or saline and completed an assessment of the acoustic startle reflex, using electromyography (EMG), with varying emotional foregrounds. Oxytocin had no impact on the affective modulation of the startle eye blink response, but significantly diminished the acoustic startle reflex irrespective of the emotional foreground. The results suggest that oxytocin facilitates prosocial behavior, in part, by attenuating basic physiological arousal. The dampening effect of oxytocin on EMG startle could possibly be used as an inexpensive marker of oxytocin's effect on limbic brain circuits.

PMID: 25082371 [PubMed - indexed for MEDLINE]