Keyword search (3,448 papers available)


Tuning Electrostatics to Promote Ordered Monolayers of Phosphole-Lipids

Author(s): Alinia Z; Miao D; Baumgartner T; DeWolf CE;

Heteroatom-doped p-conjugated systems have been exploited for electronic device applications. Phosphole-containing backbones are particularly intriguing with regard to electron delocalization and ultimately control over the photophysical, redox, and charge ...

Article GUID: 39380352
Manganese-enriched CsPbCl3 perovskite nanocrystals for self-assembled supercrystals

Author(s): Lapointe V; Majewski MB;

The self-assembly of CsPbCl3 perovskite nanocrystals and their Mn2+-enriched analogs into supercrystals is reported. Increasing Mn2+ content in the nanocrystals leads to formation of larger, increasingly uniform cubic supercrystals that eventually become ro...

Article GUID: 39347586
Rare-earth acetates as alternative precursors for rare-earth cluster-based metal-organic frameworks

Author(s): Richezzi M; Donnarumma PR; Copeman C; Howarth AJ;

RE-UiO-66 analogues are synthesized using RE acetates as precursors for the first time. These MOFs are fully characterized and the influence of the precursor on the materials obtained is studied. Additionally, the influence of water on the yield of the synt...

Article GUID: 38646995
Long live(d) CsPbBr3 superlattices: colloidal atomic layer deposition for structural stability

Author(s): Lapointe V; Green PB; Chen AN; Buonsanti R; Majewski MB;

Superlattice formation afforded by metal halide perovskite nanocrystals has been a phenomenon of interest due to the high structural order induced in these self-assemblies, an order that is influenced by the surface chemistry and particle morphology of the ...

Article GUID: 38516096
Silica-coated LiYF4:Yb3+, Tm3+ upconverting nanoparticles are non-toxic and activate minor stress responses in mammalian cells

Author(s): Bietar K; Chu S; Mandl G; Zhang E; Chabaytah N; Sabelli R; Capobianco JA; Stochaj U;

Lanthanide-doped upconverting nanoparticles (UCNPs) are ideal candidates for use in biomedicine. The interaction of nanomaterials with biological systems determines whether they are suitable for use in living cells. In-depth knowledge of the nano-bio intera...

Article GUID: 38495986
Cooperative Sensitization Upconversion in Solution Dispersions of Co-Crystal Assemblies of Mononuclear Yb3+ and Eu3+ Complexes

Author(s): Sun G; Xie Y; Wang Y; Mandl GA; Maurizio SL; Zhang H; Ottenwaelder X; Capobianco JA; Sun L;...

Lanthanide upconversion luminescence in nanoparticles has prompted continuous breakthroughs in information storage, temperature sensing, and biomedical applications, among others. Achieving upconve...

Article GUID: 37040148
A biophysical study of tear film lipid layer model membranes

Author(s): Keramatnejad M; DeWolf C;

Tear film lipid layer (TFLL), the final layer of the human tear film is responsible for surface tension reduction while blinking, water evaporation retardation and maintaining the stability of the tear film. The study of the composition-structure-function r...

Article GUID: 36535341
Upconversion Luminescence through Cooperative and Energy-Transfer Mechanisms in Yb3+ -Metal-Organic Frameworks

Author(s): Xie Y; Sun G; Mandl GA; Maurizio SL; Chen J; Capobianco JA; Sun L;

Lanthanide-doped metal-organic frameworks (Ln-MOFs) have versatile luminescence properties, however it is challenging to achieve lanthanide-based upconversion luminescence in these materials. Here, 1,3,5-benzenetricarboxylic acid (BTC) and trivalent Yb3+ io...

Article GUID: 36437239
Investigating the reactive oxygen species production of Rose Bengal and Merocyanine 540-loaded radioluminescent nanoparticles

Author(s): Nsubuga A; Mandl GA; Capobianco JA;

Radioluminescent nanomaterials have garnered significant attention in the past decade due to their potential to perform X-ray mediated photodynamic therapy (X-PDT). Many of these materials are assumed to produce singlet oxygen based on a single assay. Herei...

Article GUID: 36132856
On the photostability and luminescence of dye-sensitized upconverting nanoparticles using modified IR820 dyes

Author(s): Kaur M; Mandl GA; Maurizio SL; Tessitore G; Capobianco JA;

Dye sensitization is a promising route to enhance luminescence from lanthanide-doped upconverting nanoparticles (LnUCNPs) by improving the photon harvesting capability of LnUCNPs through the use of dye molecules, characterized by higher absorption coefficie...

Article GUID: 36132705
Cytotoxicity and Genotoxicity of Azobenzene-Based Polymeric Nanocarriers for Phototriggered Drug Release and Biomedical Applications

Author(s): Londoño-Berrío M; Pérez-Buitrago S; Ortiz-Trujillo IC; Hoyos-Palacio LM; Orozco LY; López L; Zárate-Triviño DG; Capobianco JA; Mena-Giraldo ...

Drug nanoencapsulation increases the availability, pharmacokinetics, and concentration efficiency for therapeutic regimes. Azobenzene light-responsive molecules experience a hydrophobicity change f...

Article GUID: 35956634
Mechanisms of hypericin incorporation to explain the photooxidation outcomes in phospholipid biomembrane models

Author(s): Pereira LSA; Camacho SA; Almeida AM; Gonçalves RS; Caetano W; DeWolf C; Aoki PHB;

Cell membranes are the first barriers for drug binding and key for the action of photosensitizers (PS). Herein, we report on the incorporation of the PS hypericin into Langmuir monolayers of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-dioleoyl-s...

Article GUID: 35167859
Evaluation of Lanthanide-Doped Upconverting Nanoparticles for in Vitro and in Vivo Applications

Author(s): Samhadaneh DM; Mandl GA; Han Z; Mahjoob M; Weber SC; Tuznik M; Rudko DA; Capobianco JA; Stochaj U;...

Because of their unique physicochemical properties, lanthanide-doped upconverting nanoparticles (Ln-UCNPs) have exceptional potential for biological applications. However, the use in biological sys...

Article GUID: 35025434
Binary Cu2-xS Templates Direct the Formation of Quaternary Cu2ZnSnS4 (Kesterite, Wurtzite) Nanocrystals

Author(s): Yarur Villanueva F; Green PB; Qiu C; Ullah SR; Buenviaje K; Howe JY; Majewski MB; Wilson MWB;...

Kesterite Cu2ZnSnS4 (k-CZTS) nanocrystals have received attention for their tunable optoelectronic properties, as well as the earth abundance of their constituent atoms. However, the phase-pure syn...

Article GUID: 34705409
Elucidating the mechanism of dual-fluorescence in carbon dots

Author(s): Macairan JR; de Medeiros TV; Gazzetto M; Yarur Villanueva F; Cannizzo A; Naccache R;

Carbon dots have garnered significant attention owing to their versatile and highly tunable optical properties; however, the origins and the underlying mechanism remains a subject of debate especially for dual fluorescent systems. Here, we have prepared car...

Article GUID: 34388574
A historical perspective on porphyrin-based metal-organic frameworks and their applications

Author(s): Zhang X; Wasson MC; Shayan M; Berdichevsky EK; Ricardo-Noordberg J; Singh Z; Papazyan EK; Castro AJ; Marino P; Ajoyan Z; Chen Z; Islamoglu T...

Porphyrins are important molecules widely found in nature in the form of enzyme active sites and visible light absorption units. Recent interest in using these functional molecules as building bloc...

Article GUID: 33678810
Thermal properties of lipid bilayers derived from the transient heating regime of upconverting nanoparticles

Author(s): Bastos ARN; Brites CDS; Rojas-Gutierrez PA; Ferreira RAS; Longo RL; DeWolf C; Capobianco JA; Carlos LD;...

Heat transfer and thermal properties at the nanoscale can be challenging to obtain experimentally. These are potentially relevant for understanding thermoregulation in cells. Experimental data from...

Article GUID: 33283824
On a local (de-)trapping model for highly doped Pr3+ radioluminescent and persistent luminescent nanoparticles

Author(s): Mandl GA; Van der Heggen D; Cooper DR; Joos JJ; Seuntjens J; Smet PF; Capobianco JA;

Trivalent praseodymium exhibits a wide range of luminescent phenomena when doped into a variety of different materials. Herein, radioluminescent NaLuF4:20%Pr3+ nanoparticles are studied. Four different samples of this composition were prepared ranging from ...

Article GUID: 33030192
The Key Role of Intrinsic Lifetime Dynamics from Upconverting Nanosystems in Multiemission Particle Velocimetry

Author(s): Tessitore G; Maurizio SL; Sabri T; Skinner CD; Capobianco JA;

Evaluation of particle dynamics at the nano- and microscale poses a challenge to the development of novel velocimetry techniques. Established optical methods implement external or internal calibrations of the emission profiles by varying the particle veloci...

Article GUID: 32924221
Molecular Copper(I)-Copper(II) Photosensitizer-Catalyst Photoelectrode for Water Oxidation.

Author(s): Singh Z, Donnarumma PR, Majewski MB

Copper(II)-based electrocatalysts for water oxidation in aqueous solution have been studied previously, but photodriving these systems still remains a challenge. In this work, a bis(diimine)copper(I)-based donor-chromophore-acceptor system is synthesized an...

Article GUID: 32909755
Wavelength-Selective Nonlinear Imaging and Photo-Induced Cell Damage by Dielectric Harmonic Nanoparticles.

Author(s): Kilin V, Campargue G, Fureraj I, Sakong S, Sabri T, Riporto F, Vieren A, Mugnier Y, Mas C, Staedler D, Collins JM, Bonacina L, Vogel A, Capobianco JA, Wolf JP

ACS Nano. 2020 Apr 16;: Authors: Kilin V, Campargue G, Fureraj I, Sakong S, Sabri T, Riporto F, Vieren A, Mugnier Y, Mas C, Staedler D, Collins JM, Bonacina L, Vogel A, Capobianco JA, Wolf JP

Article GUID: 32282184
The antibacterial activity of p-tert-butylcalix[6]arene and its effect on a membrane model: molecular dynamics and Langmuir film studies.

Author(s): Wrobel EC, de Lara LS, do Carmo TAS, Castellen P, Lazzarotto M, de Lázaro SR, Camilo A, Caseli L, Schmidt R, DeWolf CE, Wohnrath K

Phys Chem Chem Phys. 2020 Mar 03;: Authors: Wrobel EC, de Lara LS, do Carmo TAS, Castellen P, Lazzarotto M, de Lázaro SR, Camilo A, Caseli L, Schmidt R, DeWolf CE, Wohnrath K

Article GUID: 32124897
Interfacial Self-Assembly of Antimicrobial Peptide GL13K into Non-Fibril Crystalline β-Sheets.

Author(s): Youssef H, DeWolf CE

Langmuir. 2020 Jan 06;: Authors: Youssef H, DeWolf CE

Article GUID: 31880463
Strong Headgroup Interactions Drive Highly Directional Growth and Unusual Phase Co-Existence in Self-Assembled Phenolic Films.

Author(s): Miclette Lamarche R, DeWolf C

ACS Appl Mater Interfaces. 2019 Nov 22;: Authors: Miclette Lamarche R, DeWolf C

Article GUID: 31710200
Optically Stimulated Nanodosimeters with High Storage Capacity.

Author(s): Van der Heggen D, Cooper DR, Tesson M, Joos JJ, Seuntjens J, Capobianco JA, Smet PF

Nanomaterials (Basel). 2019 Aug 05;9(8): Authors: Van der Heggen D, Cooper DR, Tesson M, Joos JJ, Seuntjens J, Capobianco JA, Smet PF

Article GUID: 31387200
Reduction-Responsive Sheddable Carbon Nanotubes Dispersed in Aqueous Solution.

Author(s): An SY, Sun S, Oh JK

Macromol Rapid Commun. 2016 Apr;37(8):705-10 Authors: An SY, Sun S, Oh JK

Article GUID: 26890479
Intrinsic Time-Tunable Emissions in Core-Shell Upconverting Nanoparticle Systems.

Author(s): Tessitore G, Maurizio SL, Sabri T, Capobianco JA

Angew Chem Int Ed Engl. 2019 Jun 04;: Authors: Tessitore G, Maurizio SL, Sabri T, Capobianco JA

Article GUID: 31161694
Model Lung Surfactant Films: Why Composition Matters.

Author(s): Selladurai SL, Miclette Lamarche R, Schmidt R, DeWolf CE

Langmuir. 2016 Oct 18;32(41):10767-10775 Authors: Selladurai SL, Miclette Lamarche R, Schmidt R, DeWolf CE

Article GUID: 27641759
A NIR-responsive azobenzene-based supramolecular hydrogel using upconverting nanoparticles.

Author(s): Mandl GA, Rojas-Gutierrez PA, Capobianco JA

Chem Commun (Camb). 2018 Jun 05;54(46):5847-5850 Authors: Mandl GA, Rojas-Gutierrez PA, Capobianco JA

Article GUID: 29726556
Dual Activity of Rose Bengal Functionalized to Albumin-Coated Lanthanide-Doped Upconverting Nanoparticles: Targeting and Photodynamic Therapy.

Author(s): Sabri T, Pawelek PD, Capobianco JA

ACS Appl Mater Interfaces. 2018 Aug 15;10(32):26947-26953 Authors: Sabri T, Pawelek PD, Capobianco JA

Article GUID: 30028124
Perspective: lanthanide-doped upconverting nanoparticles.

Author(s): Mandl GA, Cooper DR, Hirsch T, Seuntjens J, Capobianco JA

Methods Appl Fluoresc. 2019 Jan 21;7(1):012004 Authors: Mandl GA, Cooper DR, Hirsch T, Seuntjens J, Capobianco JA

Article GUID: 30572318
Structural organization and phase behaviour of meta-substituted dioctadecylaminobenzoquinones at the air/water interface.

Author(s): Behyan S, Gritzalis D, Schmidt R, Kebede E, Cuccia LA, DeWolf C

Phys Chem Chem Phys. 2019 Jan 30;21(5):2345-2350 Authors: Behyan S, Gritzalis D, Schmidt R, Kebede E, Cuccia LA, DeWolf C

Article GUID: 30657501
Recent insights into upconverting nanoparticles: spectroscopy, modeling, and routes to improved luminescence.

Author(s): Tessitore G, Mandl GA, Brik MG, Park W, Capobianco JA

Nanoscale. 2019 May 23;: Authors: Tessitore G, Mandl GA, Brik MG, Park W, Capobianco JA

Article GUID: 31120083
Title:A biophysical study of tear film lipid layer model membranes
Authors:Keramatnejad M,  DeWolf C, 
Link:https://pubmed.ncbi.nlm.nih.gov/36535341/
DOI:10.1016/j.bbamem.2022.184102
Category:
PMID:36535341
Dept Affiliation: CNSR
1 Department of Chemistry & Biochemistry, Centre for Nanoscience Research, Concordia University,7141 Sherbrooke Street west, H4B1R6 Montreal, Canada. Electronic address: Mahshid.Keramatnejad@concordia.ca.
2 Department of Chemistry & Biochemistry, Centre for Nanoscience Research, Concordia University,7141 Sherbrooke Street west, H4B1R6 Montreal, Canada. Electronic address: Christine.DeWolf@concordia.ca.

Description:

Tear film lipid layer (TFLL), the final layer of the human tear film is responsible for surface tension reduction while blinking, water evaporation retardation and maintaining the stability of the tear film. The study of the composition-structure-function relationship of TFLL is paramount, as a compromised structure of TFLL leads to the emergence of dry eye disease (DED) which is one the most prevalent ophthalmic surface diseases of the modern world, associated with chronic pain and reduced visual capability. In this model membrane study, a systematic approach is used to study the biophysical properties of TFLL model membranes as a function of composition. Three mixed-lipid model membranes are studied along with their individual components comprising cholesteryl oleate (CO), glyceryl trioleate (GT), L-a-phosphatidylcholine (egg PC) and a free fatty acid mixture. The models become progressively more complex from binary to quaternary mixtures, allowing the role of each individual lipid to be derived. Langmuir balance, Brewster Angle Microscopy (BAM) and Profile Analysis Tensiometer (PAT) are used to study the surface activity and compression-expansion cycles, morphology, and rheological behaviour of the model membranes, respectively. Evidence of multilayering is observed with inclusion of CO and a reversible collapse is associated with the GT phase transition. An initially more coherent film is observed due to the addition of polar PC. Notably, these individual behaviours are retained in the mixed films and suggest a possible role for each physiological component of TFLL.