Keyword search (3,261 papers available)


Dynamics of karyotype evolution

Author(s): Kuzmin E; Baker TM; Van Loo P; Glass L;

In the evolution of species, the karyotype changes with a timescale of tens to hundreds of thousand years. In the development of cancer, the karyotype often is modified in cancerous cells over the lifetime of an individual. Characterizing these changes and ...

Article GUID: 38717409

Genome and secretome insights: unravelling the lignocellulolytic potential of Myceliophthora verrucosa for enhanced hydrolysis of lignocellulosic biomass

Author(s): Sharma G; Kaur B; Singh V; Raheja Y; Falco MD; Tsang A; Chadha BS;

Lignocellulolytic enzymes from a novel Myceliophthora verrucosa (5DR) strain was found to potentiate the efficacy of benchmark cellulase during saccharification of acid/alkali treated bagasse by ~ 2.24 fold, indicating it to be an important source of auxili...

Article GUID: 38676717

Exploiting protein language models for the precise classification of ion channels and ion transporters

Author(s): Ghazikhani H; Butler G;

This study introduces TooT-PLM-ionCT, a comprehensive framework that consolidates three distinct systems, each meticulously tailored for one of the following tasks: distinguishing ion channels (ICs) from membrane proteins (MPs), segregating ion transporters...

Article GUID: 38656743

Substrate specificity mapping of fungal CAZy AA3_2 oxidoreductases

Author(s): Zhao H; Karppi J; Mototsune O; Poshina D; Svartström J; Nguyen TTM; Vo TM; Tsang A; Master E; Tenkanen M;...

Background: Oxidative enzymes targeting lignocellulosic substrates are presently classified into various auxiliary activity (AA) families within the carbohydrate-active enzyme (CAZy) database. Amon...

Article GUID: 38539167

A thermostable and inhibitor resistant β-glucosidase from Rasamsonia emersonii for efficient hydrolysis of lignocellulosics biomass

Author(s): Raheja Y; Singh V; Sharma G; Tsang A; Chadha BS;

The present study reports a highly thermostable ß-glucosidase (GH3) from Rasamsonia emersonii that was heterologously expressed in Pichia pastoris. Extracellular ß-glucosidase was purified to homogeneity using single step affinity chromatography with molecu...

Article GUID: 38470501

Comparative analysis of functional diversity of rumen microbiome in bison and beef heifers

Author(s): Nguyen TTM; Badhan AK; Reid ID; Ribeiro G; Gruninger R; Tsang A; Guan LL; McAllister T;

Ruminants play a key role in the conversion of cellulolytic plant material into high-quality meat and milk protein for humans. The rumen microbiome is the driver of this conversion, yet there is little information on how gene expression within the microbiom...

Article GUID: 38054735

Functional screening pipeline to uncover laccase-like multicopper oxidase enzymes that transform industrial lignins

Author(s): Sharan AA; Bellemare A; DiFalco M; Tsang A; Vuong TV; Edwards EA; Master ER;

Laccase-like multicopper oxidases are recognized for their potential to alter the reactivity of lignins for application in value-added products. Typically, model compounds are employed to discover such enzymes; however, they do not represent the complexity ...

Article GUID: 38000639

Author Correction: Native diversity buffers against severity of non-native tree invasions

Author(s): Delavaux CS; Crowther TW; Zohner CM; Robmann NM; Lauber T; van den Hoogen J; Kuebbing S; Liang J; de-Miguel S; Nabuurs GJ; Reich PB; Abegg M; Adou Yao YC; Alberti G; Almeyda Zambrano AM; Alvarado B...

No abstract

Article GUID: 37752352

Identification of a Conserved Transcriptional Activator-Repressor Module Controlling the Expression of Genes Involved in Tannic Acid Degradation and Gallic Acid Utilization in Aspergillus niger

Author(s): Arentshorst M; Falco MD; Moisan MC; Reid ID; Spaapen TOM; van Dam J; Demirci E; Powlowski J; Punt PJ; Tsang A; Ram AFJ;...

Tannic acid, a hydrolysable gallotannin present in plant tissues, consists of a central glucose molecule esterified with gallic acid molecules. Some microorganisms, including several Aspergillus sp...

Article GUID: 37744122

Utilization of ferulic acid in Aspergillus niger requires the transcription factor FarA and a newly identified Far-like protein (FarD) that lacks the canonical Zn(II)2Cys6 domain

Author(s): Arentshorst M; Reijngoud J; van Tol DJC; Reid ID; Arendsen Y; Pel HJ; van Peij NNME; Visser J; Punt PJ; Tsang A; Ram AFJ;...

The feruloyl esterase B gene (faeB) is specifically induced by hydroxycinnamic acids (e.g. ferulic acid, caffeic acid and coumaric acid) but the transcriptional regulation network involved in faeB ...

Article GUID: 37746181

Functional characterization of fungal lytic polysaccharide monooxygenases for cellulose surface oxidation

Author(s): Mathieu Y; Raji O; Bellemare A; Di Falco M; Nguyen TTM; Viborg AH; Tsang A; Master E; Brumer H;...

Background: Microbial lytic polysaccharide monooxygenases (LPMOs) cleave diverse biomass polysaccharides, including cellulose and hemicelluloses, by initial oxidation at C1 or C4 of glycan chains. ...

Article GUID: 37679837

CRISPR/Cas9 mediated gene editing of transcription factor ACE1 for enhanced cellulase production in thermophilic fungus Rasamsonia emersonii

Author(s): Singh V; Raheja Y; Basotra N; Sharma G; Tsang A; Chadha BS;

Background: The filamentous fungus Rasamsonia emersonii has immense potential to produce biorefinery relevant thermostable cellulase and hemicellulase enzymes using lignocellulosic biomass. Previously in our lab, a hyper-cellulase producing strain of R. eme...

Article GUID: 37658430

Native diversity buffers against severity of non-native tree invasions

Author(s): Delavaux CS; Crowther TW; Zohner CM; Robmann NM; Lauber T; van den Hoogen J; Kuebbing S; Liang J; de-Miguel S; Nabuurs GJ; Reich PB; Abegg M...

Determining the drivers of non-native plant invasions is critical for managing native ecosystems and limiting the spread of invasive species1,2. Tree invasions in particular have been relatively ov...

Article GUID: 37612513

Identification of Genes Involved in the Degradation of Lignocellulose Using Comparative Transcriptomics

Author(s): Gruninger RJ; Tsang A; McAllister TA;

Lignocellulosic biomass represents an abundant, renewable resource that can be used to produce biofuels, low-cost livestock feed, and high-value chemicals. The potential of this bioresource has led to intensive research efforts to develop cost-effective met...

Article GUID: 37149538

A "biphasic glycosyltransferase high-throughput screen" identifies novel anthraquinone glycosides in the diversification of phenolic natural products

Author(s): Mohideen FI; Kwan DH;

The sugar moieties of many glycosylated small molecule natural products are essential for their biological activity. Glycosyltransferases (GTs) are the enzymes responsible for installing these sugar moieties on a variety of biomolecules. Several GTs that ar...

Article GUID: 36682498

Xylan glucuronic acid side chains fix suberin-like aliphatic compounds to wood cell walls

Author(s): Derba-Maceluch M; Mitra M; Hedenström M; Liu X; Gandla ML; Barbut FR; Abreu IN; Donev EN; Urbancsok J; Moritz T; Jönsson LJ; Tsang A; Powlow...

Wood is the most important repository of assimilated carbon in the biosphere, in the form of large polymers (cellulose, hemicelluloses including glucuronoxylan, and lignin) that interactively form ...

Article GUID: 36600379

Characterization of a novel AA3_1 xylooligosaccharide dehydrogenase from Thermothelomyces myriococcoides CBS 398.93

Author(s): Zhao H; Karppi J; Nguyen TTM; Bellemare A; Tsang A; Master E; Tenkanen M;

Background: The Carbohydrate-Active enZymes (CAZy) auxiliary activity family 3 (AA3) comprises flavin adenine dinucleotide-dependent (FAD) oxidoreductases from the glucose-methanol-choline (GMC) family, which play auxiliary roles in lignocellulose conversio...

Article GUID: 36476312

Rosemary essential oil and its components 1,8-cineole and α-pinene induce ROS-dependent lethality and ROS-independent virulence inhibition in Candida albicans

Author(s): Shahina Z; Al Homsi R; Price JDW; Whiteway M; Sultana T; Dahms TES;

The essential oil from Rosmarinus officinalis L., a composite mixture of plant-derived secondary metabolites, exhibits antifungal activity against virulent candidal species. Here we report the impact of rosemary oil and two of its components, the monoterpen...

Article GUID: 36383525

Bioreactor as the root cause of the "manganese effect" during Aspergillus niger citric acid fermentations

Author(s): Fekete E; Bíró V; Márton A; Bakondi-Kovács I; Németh Z; Sándor E; Kovács B; Fábián I; Kubicek CP; Tsang A; Karaffa L;...

High-yield citric acid production by the filamentous Ascomycete fungus Aspergillus niger requires a combination of extreme nutritional conditions, of which maintaining a low manganese (II) ion conc...

Article GUID: 35992333

Comparative Analysis of Enzyme Production Patterns of Lignocellulose Degradation of Two White Rot Fungi: Obba rivulosa and Gelatoporia subvermispora

Author(s): Marinovíc M; Di Falco M; Aguilar Pontes MV; Gorzsás A; Tsang A; de Vries RP; Mäkelä MR; Hildén K;...

The unique ability of basidiomycete white rot fungi to degrade all components of plant cell walls makes them indispensable organisms in the global carbon cycle. In this study, we analyzed the prote...

Article GUID: 35892327

Improving candidate Biosynthetic Gene Clusters in fungi through reinforcement learning

Author(s): Almeida H; Tsang A; Diallo AB;

Motivation: Precise identification of Biosynthetic Gene Clusters (BGCs) is a challenging task. Performance of BGC discovery tools is limited by their capacity to accurately predict components belonging to candidate BGCs, often overestimatin...

Article GUID: 35762945

Lignocellulolytic enzymes from Aspergillus allahabadii for efficient bioconversion of rice straw into fermentable sugars and biogas

Author(s): Sharma G; Kaur B; Raheja Y; Agrawal D; Basotra N; Di Falco M; Tsang A; Singh Chadha B;

The study was aimed at developing lignocellulolytic strain capable of efficient hydrolysis of mild alkali deacetylated (MAD) rice straw. The valorisation of lignin rich black liquor obtained during pre-treatment of rice straw into biogas was also evaluated....

Article GUID: 35753566

Carbohydrate esterase family 16 contains fungal hemicellulose acetyl esterases (HAEs) with varying specificity

Author(s): Venegas FA; Koutaniemi S; Langeveld SMJ; Bellemare A; Chong SL; Dilokpimol A; Lowden MJ; Hilden KS; Leyva-Illades JF; Mäkelä MR; My Pham TT;...

Acetyl esterases are an important component of the enzymatic machinery fungi use to degrade plant biomass and are classified in several Carbohydrate Esterase families of the CAZy classification sys...

Article GUID: 35405333

Combination of system biology and classical approaches for developing biorefinery relevant lignocellulolytic Rasamsonia emersonii strain

Author(s): Raheja Y; Singh V; Kaur B; Basotra N; Di Falco M; Tsang A; Singh Chadha B;

The objective of this study was to develop thermophilic fungus Rasamsonia emersonii using integrated system biology tools (genomics, proteomics and transcriptional analysis) in combination with classical strain breeding approaches. Developed hyper celluloly...

Article GUID: 35318142

A Versatile Transcription Factor Biosensor System Responsive to Multiple Aromatic and Indole Inducers

Author(s): Nasr MA; Timmins LR; Martin VJJ; Kwan DH;

Allosteric transcription factor (aTF) biosensors are valuable tools for engineering microbes toward a multitude of applications in metabolic engineering, biotechnology, and synthetic biology. One of the challenges toward constructing functional and diverse ...

Article GUID: 35316041

Screening of novel fungal Carbohydrate Esterase family 1 enzymes identifies three novel dual feruloyl/acetyl xylan esterases

Author(s): Dilokpimol A; Verkerk B; Li X; Bellemare A; Lavallee M; Frommhagen M; Nørmølle Underlin E; Kabel MA; Powlowski J; Tsang A; de Vries RP;...

Feruloyl esterases (FAEs) and acetyl xylan esterases (AXEs) are important enzymes for plant biomass degradation and are both present in Carbohydrate Esterase family 1 (CE1) of the Carbohydrate-Acti...

Article GUID: 35187647

Southeast Asian Dipterocarp origin and diversification driven by Africa-India floristic interchange

Author(s): Bansal M; Morley RJ; Nagaraju SK; Dutta S; Mishra AK; Selveraj J; Kumar S; Niyolia D; Harish SM; Abdelrahim OB; Hasan SE; Ramesh BR; Dayanan...

The evolution and diversification of ancient megathermal angiosperm lineages with Africa-India origins in Asian tropical forests is poorly understood because of the lack of reliable fossils. Our pa...

Article GUID: 35084986

Electrochemical nutrient removal from natural wastewater sources and its impact on water quality

Author(s): Kékedy-Nagy L; English L; Anari Z; Abolhassani M; Pollet BG; Popp J; Greenlee LF;

In this study, a suite of natural wastewater sources is tested to understand the effects of wastewater composition and source on electrochemically driven nitrogen and phosphorus nutrient removal. Kinetics, electrode behavior, and removal efficiency were eva...

Article GUID: 34974342

In Vitro Reconstitution of the dTDP-l-Daunosamine Biosynthetic Pathway Provides Insights into Anthracycline Glycosylation

Author(s): Mohideen FI; Nguyen LH; Richard JD; Ouadhi S; Kwan DH;

Many small molecule natural products are decorated with sugar moieties that are essential for their biological activity. A considerable number of natural product glycosides and their derivatives are clinically important therapeutics. Anthracyclines like dau...

Article GUID: 34751552

Economizing the lignocellulosic hydrolysis process using heterologously expressed auxiliary enzymes feruloyl esterase D (CE1) and β-xylosidase (GH43) derived from thermophilic fungi Scytalidium thermophilum

Author(s): Agrawal D; Tsang A; Chadha BS;

Two lignocellulolytic accessory enzymes, feruloyl esterase D (FAED_SCYTH) and ß-xylosidase (XYL43B_SCYTH) were cloned and produced in the Pichia pastoris X33 as host. The molecular weight of recombinant enzymes FAED_SCYTH and XYL43B_SCYTH were ~ 31 and 40 k...

Article GUID: 34293687

The chimeric GaaR-XlnR transcription factor induces pectinolytic activities in the presence of D-xylose in Aspergillus niger

Author(s): Kun RS; Garrigues S; Di Falco M; Tsang A; de Vries RP;

Aspergillus niger is a filamentous fungus well known for its ability to produce a wide variety of pectinolytic enzymes, which have many applications in the industry. The transcriptional activator GaaR is induced by 2-keto-3-deoxy-L-galactonate, a compound d...

Article GUID: 34236481

Blocking utilization of major plant biomass polysaccharides leads Aspergillus niger towards utilization of minor components

Author(s): Kun RS; Garrigues S; Di Falco M; Tsang A; de Vries RP;

Fungi produce a wide range of enzymes that allow them to grow on diverse plant biomass. Wheat bran is a low-cost substrate with high potential for biotechnological applications. It mainly contains cellulose and (arabino)xylan, as well as starch, proteins, l...

Article GUID: 34114741

Loss of function of the carbon catabolite repressor CreA leads to low but inducer-independent expression from the feruloyl esterase B promoter in Aspergillus niger

Author(s): Reijngoud J; Arentshorst M; Ruijmbeek C; Reid I; Alazi ED; Punt PJ; Tsang A; Ram AFJ;

Objective: With the aim to decipher the mechanisms involved in the transcriptional regulation of feruloyl esterase encoded by faeB, a genetic screen was performed to isolate A. niger mutants displaying inducer-independent expression from the faeB promoter. ...

Article GUID: 33738610

Genetic Characterization of Mutations Related to Conidiophore Stalk Length Development in Aspergillus niger Laboratory Strain N402

Author(s): Demirci E; Arentshorst M; Yilmaz B; Swinkels A; Reid ID; Visser J; Tsang A; Ram AFJ;

Aspergillus niger is an important filamentous fungus in industrial biotechnology for the production of citric acid and enzymes. In the late 1980s, the A. niger N400/NRRL3 strain was selected for both fundamental and applied studies in relation to several pr...

Article GUID: 33959152

TOUCAN: a framework for fungal biosynthetic gene cluster discovery.

Author(s): Almeida H, Palys S, Tsang A, Diallo AB

Fungal secondary metabolites (SMs) are an important source of numerous bioactive compounds largely applied in the pharmaceutical industry, as in the production of antibiotics and anticancer medications. The discovery of novel fungal SMs can potentially bene...

Article GUID: 33575642

Resources and Methods for Engineering "Designer" Glycan-Binding Proteins.

Author(s): Warkentin R, Kwan DH

This review provides information on available methods for engineering glycan-binding proteins (GBP). Glycans are involved in a variety of physiological functions and are found in all domains of life and viruses. Due to their wide range of functions, GBPs ha...

Article GUID: 33450899

Integrative approach for detecting membrane proteins.

Author(s): Alballa M, Butler G

BACKGROUND: Membrane proteins are key gates that control various vital cellular functions. Membrane proteins are often detected using transmembrane topology prediction tools. While transmembrane topology prediction tools can detect integral membrane protein...

Article GUID: 33349234

Deletion of the Aspergillus niger Pro-Protein Processing Protease Gene kexB Results in a pH-Dependent Morphological Transition during Submerged Cultivations and Increases Cell Wall Chitin Content.

Author(s): van Leeuwe TM, Arentshorst M, Forn-Cuní G, Geoffrion N, Tsang A, Delvigne F, Meijer AH, Ram AFJ, Punt PJ...

There is a growing interest in the use of post-fermentation mycelial waste to obtain cell wall chitin as an added-value product. In the pursuit to identify suitable production strains that can be u...

Article GUID: 33276589

Ecosystem-level carbon storage and its links to diversity, structural and environmental drivers in tropical forests of Western Ghats, India.

Author(s): Kothandaraman S, Dar JA, Sundarapandian S, Dayanandan S, Khan ML

Sci Rep. 2020 Aug 10;10(1):13444 Authors: Kothandaraman S, Dar JA, Sundarapandian S, Dayanandan S, Khan ML

Article GUID: 32778785

Biosynthesis of Alkylcitric Acids in Aspergillus niger Involves Both Co-localized and Unlinked Genes.

Author(s): Palys S, Pham TTM, Tsang A

Front Microbiol. 2020;11:1378 Authors: Palys S, Pham TTM, Tsang A

Article GUID: 32695080

Enzymatic Synthesis of a Fluorogenic Reporter Substrate and the Development of a High-Throughput Assay for Fucosyltransferase VIII Provide a Toolkit to Probe and Inhibit Core Fucosylation.

Author(s): Soroko M, Kwan DH

Biochemistry. 2020 Jun 01;: Authors: Soroko M, Kwan DH

Article GUID: 32441090

Penicillium subrubescens adapts its enzyme production to the composition of plant biomass.

Author(s): Dilokpimol A, Peng M, Di Falco M, Chin A Woeng T, Hegi RMW, Granchi Z, Tsang A, Hildén KS, Mäkelä MR, de Vries RP

Bioresour Technol. 2020 May 05;311:123477 Authors: Dilokpimol A, Peng M, Di Falco M, Chin A Woeng T, Hegi RMW, Granchi Z, Tsang A, Hildén KS, Mäkelä MR, de Vries RP

Article GUID: 32408196

Effect of ammonia fiber expansion-treated wheat straw and a recombinant fibrolytic enzyme on rumen microbiota and fermentation parameters, total tract digestibility, and performance of lambs.

Author(s): Ribeiro GO; Gruninger RJ; Jones DR; Beauchemin KA; Yang WZ; Wang Y; Abbott DW; Tsang A; McAllister TA;...

The objective of this study was to evaluate the effect of ammonia fiber expansion (AFEX)-treated wheat straw pellets and a recombinant fibrolytic enzyme on the rumen microbiome, rumen fermentation ...

Article GUID: 32369600

TooT-T: discrimination of transport proteins from non-transport proteins.

Author(s): Alballa M, Butler G

BMC Bioinformatics. 2020 Apr 23;21(Suppl 3):25 Authors: Alballa M, Butler G

Article GUID: 32321420

Evidence for ligninolytic activity of the ascomycete fungus Podospora anserina.

Author(s): van Erven G, Kleijn AF, Patyshakuliyeva A, Di Falco M, Tsang A, de Vries RP, van Berkel WJH, Kabel MA

Biotechnol Biofuels. 2020;13:75 Authors: van Erven G, Kleijn AF, Patyshakuliyeva A, Di Falco M, Tsang A, de Vries RP, van Berkel WJH, Kabel MA

Article GUID: 32322305

Functional Characterization of Clinical Isolates of the Opportunistic Fungal Pathogen Aspergillus nidulans.

Author(s): Bastos RW, Valero C, Silva LP, Schoen T, Drott M, Brauer V, Silva-Rocha R, Lind A, Steenwyk JL, Rokas A, Rodrigues F, Resendiz-Sharpe A, Lag...

mSphere. 2020 Apr 08;5(2): Authors: Bastos RW, Valero C, Silva LP, Schoen T, Drott M, Brauer V, Silva-Rocha R, Lind A, Steenwyk JL, Rokas A, Rodrigues F, Resendiz-Sharpe A, Lagrou K, Marcet-Houben...

Article GUID: 32269156

The effects of external Mn2+ concentration on hyphal morphology and citric acid production are mediated primarily by the NRAMP-family transporter DmtA in Aspergillus niger.

Author(s): Fejes B, Ouedraogo JP, Fekete E, Sándor E, Flipphi M, Soós Á, Molnár ÁP, Kovács B, Kubicek CP, Tsang A, Karaffa L

Microb Cell Fact. 2020 Jan 30;19(1):17 Authors: Fejes B, Ouedraogo JP, Fekete E, Sándor E, Flipphi M, Soós Á, Molnár ÁP, Kovács B, Kubicek CP, Tsang A, Karaffa L

Article GUID: 32000778

TranCEP: Predicting the substrate class of transmembrane transport proteins using compositional, evolutionary, and positional information.

Author(s): Alballa M, Aplop F, Butler G

PLoS One. 2020;15(1):e0227683 Authors: Alballa M, Aplop F, Butler G

Article GUID: 31935244

Discovery and Expression of Thermostable LPMOs from Thermophilic Fungi for Producing Efficient Lignocellulolytic Enzyme Cocktails.

Author(s): Agrawal D, Basotra N, Balan V, Tsang A, Chadha BS

Appl Biochem Biotechnol. 2019 Dec 02;: Authors: Agrawal D, Basotra N, Balan V, Tsang A, Chadha BS

Article GUID: 31792786

Evolutionary adaptation of Aspergillus niger for increased ferulic acid tolerance.

Author(s): Lubbers RJM, Liwanag AJ, Peng M, Dilokpimol A, Benoit-Gelber I, de Vries RP

J Appl Microbiol. 2019 Nov 01;: Authors: Lubbers RJM, Liwanag AJ, Peng M, Dilokpimol A, Benoit-Gelber I, de Vries RP

Article GUID: 31674709

Photosystem Biogenesis Is Localized to the Translation Zone in the Chloroplast of Chlamydomonas.

Author(s): Sun Y, Valente-Paterno MI, Bakhtiari S, Law C, Zhan Y, Zerges W

Photosystem Biogenesis Is Localized to the Translation Zone in the Chloroplast of Chlamydomonas.

Plant Cell. 2019 Oct 07;:

Authors: Sun Y, Valente-Paterno MI, Bakhtiari S, Law C, Zhan Y, Zerges W

Abstract
Intracellular pro...

Article GUID: 31591163

Glucose-mediated repression of plant biomass utilization in the white-rot fungus Dichomitus squalens.

Author(s): Daly P, Peng M, Di Falco M, Lipzen A, Wang M, Ng V, Grigoriev IV, Tsang A, Mäkelä MR, de Vries RP

Appl Environ Microbiol. 2019 Oct 04;: Authors: Daly P, Peng M, Di Falco M, Lipzen A, Wang M, Ng V, Grigoriev IV, Tsang A, Mäkelä MR, de Vries RP

Article GUID: 31585998

Enzymes of early-diverging, zoosporic fungi.

Author(s): Lange L, Barrett K, Pilgaard B, Gleason F, Tsang A

Appl Microbiol Biotechnol. 2019 Jul 15;: Authors: Lange L, Barrett K, Pilgaard B, Gleason F, Tsang A

Article GUID: 31309267

Start-up of oxygen-limited autotrophic partial nitrification-anammox process for treatment of nitrite-free wastewater in a single-stage hybrid bioreactor.

Author(s): Hosseinpour B, Saborimanesh N, Yerushalmi L, Walsh D, Mulligan CN

Environ Technol. 2019 Aug 04;:1-9 Authors: Hosseinpour B, Saborimanesh N, Yerushalmi L, Walsh D, Mulligan CN

Article GUID: 31378146

Effects of a recombinant fibrolytic enzyme on fiber digestion, ruminal fermentation, nitrogen balance and total tract digestibility of heifers fed a high forage diet.

Author(s): Ran T, Saleem AM, Shen Y, Ribeiro GO, Beauchemin KA, Tsang A, Yang W, McAllister TA

Effects of a recombinant fibrolytic enzyme on fiber digestion, ruminal fermentation, nitrogen balance and total tract digestibility of heifers fed a high forage diet.
J Anim Sci. 2019 Jun 28;:
Authors: Ran T, Saleem AM, Shen Y, Ribeiro GO, Beauchemi...

Article GUID: 31251799

Expression of a library of fungal β-glucosidases in Saccharomyces cerevisiae for the development of a biomass fermenting strain.

Author(s): Wilde C, Gold ND, Bawa N, Tambor JH, Mougharbel L, Storms R, Martin VJ

Appl Microbiol Biotechnol. 2012 Aug;95(3):647-59 Authors: Wilde C, Gold ND, Bawa N, Tambor JH, Mougharbel L, Storms R, Martin VJ

Article GUID: 22218767

A molecular phylogeny of thermophilic fungi.

Author(s): Morgenstern I, Powlowski J, Ishmael N, Darmond C, Marqueteau S, Moisan MC, Quenneville G, Tsang A

Fungal Biol. 2012 Apr;116(4):489-502 Authors: Morgenstern I, Powlowski J, Ishmael N, Darmond C, Marqueteau S, Moisan MC, Quenneville G, Tsang A

Article GUID: 22483047

A retinoblastoma orthologue is a major regulator of S-phase, mitotic, and developmental gene expression in Dictyostelium.

Author(s): Strasser K, Bloomfield G, MacWilliams A, Ceccarelli A, MacWilliams H, Tsang A

PLoS One. 2012;7(6):e39914 Authors: Strasser K, Bloomfield G, MacWilliams A, Ceccarelli A, MacWilliams H, Tsang A

Article GUID: 22768168

Biogenic membranes of the chloroplast in Chlamydomonas reinhardtii.

Author(s): Schottkowski M, Peters M, Zhan Y, Rifai O, Zhang Y, Zerges W

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19286-91 Authors: Schottkowski M, Peters M, Zhan Y, Rifai O, Zhang Y, Zerges W

Article GUID: 23129655

Effects of synthetic cohesin-containing scaffold protein architecture on binding dockerin-enzyme fusions on the surface of Lactococcus lactis.

Author(s): Wieczorek AS, Martin VJ

Microb Cell Fact. 2012 Dec 15;11:160 Authors: Wieczorek AS, Martin VJ

Article GUID: 23241215

The folding capacity of the mature domain of the dual-targeted plant tRNA nucleotidyltransferase influences organelle selection.

Author(s): Leibovitch M, Bublak D, Hanic-Joyce PJ, Tillmann B, Flinner N, Amsel D, Scharf KD, Mirus O, Joyce PB, Schleiff E

Biochem J. 2013 Aug 01;453(3):401-12 Authors: Leibovitch M, Bublak D, Hanic-Joyce PJ, Tillmann B, Flinner N, Amsel D, Scharf KD, Mirus O, Joyce PB, Schleiff E

Article GUID: 23713568

The production and characterization of a new active lipase from Acremonium alcalophilum using a plant bioreactor.

Author(s): Pereira EO, Tsang A, McAllister TA, Menassa R

Biotechnol Biofuels. 2013;6:111 Authors: Pereira EO, Tsang A, McAllister TA, Menassa R

Article GUID: 23915965

Gene expression analysis in the roots of salt-stressed wheat and the cytogenetic derivatives of wheat combined with the salt-tolerant wheatgrass, Lophopyrum elongatum.

Author(s): Hussein Z, Dryanova A, Maret D, Gulick PJ

Plant Cell Rep. 2014 Jan;33(1):189-201 Authors: Hussein Z, Dryanova A, Maret D, Gulick PJ

Article GUID: 24141639

Do ecological niche model predictions reflect the adaptive landscape of species?: a test using Myristica malabarica Lam., an endemic tree in the Western Ghats, India.

Author(s): Nagaraju SK, Gudasalamani R, Barve N, Ghazoul J, Narayanagowda GK, Ramanan US

PLoS One. 2013;8(11):e82066 Authors: Nagaraju SK, Gudasalamani R, Barve N, Ghazoul J, Narayanagowda GK, Ramanan US

Article GUID: 24312402

SnowyOwl: accurate prediction of fungal genes by using RNA-Seq and homology information to select among ab initio models.

Author(s): Reid I, O'Toole N, Zabaneh O, Nourzadeh R, Dahdouli M, Abdellateef M, Gordon PM, Soh J, Butler G, Sensen CW, Tsang A

BMC Bioinformatics. 2014 Jul 01;15:229 Authors: Reid I, O'Toole N, Zabaneh O, Nourzadeh R, Dahdouli M, Abdellateef M, Gordon PM, Soh J, Butler G, Sensen CW, Tsang A

Article GUID: 24980894

Mutations in TRNT1 cause congenital sideroblastic anemia with immunodeficiency, fevers, and developmental delay (SIFD).

Author(s): Chakraborty PK, Schmitz-Abe K, Kennedy EK, Mamady H, Naas T, Durie D, Campagna DR, Lau A, Sendamarai AK, Wiseman DH, May A, Jolles S, Connor...

Blood. 2014 Oct 30;124(18):2867-71 Authors: Chakraborty PK, Schmitz-Abe K, Kennedy EK, Mamady H, Naas T, Durie D, Campagna DR, Lau A, Sendamarai AK, Wiseman DH, May A, Jolles S, Connor P, Powell C...

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The characterization of the endoglucanase Cel12A from Gloeophyllum trabeum reveals an enzyme highly active on β-glucan.

Author(s): Miotto LS, de Rezende CA, Bernardes A, Serpa VI, Tsang A, Polikarpov I

PLoS One. 2014;9(9):e108393 Authors: Miotto LS, de Rezende CA, Bernardes A, Serpa VI, Tsang A, Polikarpov I

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Enhancement of synthetic Trichoderma-based enzyme mixtures for biomass conversion with an alternative family 5 glycosyl hydrolase from Sporotrichum thermophile.

Author(s): Ye Z, Zheng Y, Li B, Borrusch MS, Storms R, Walton JD

PLoS One. 2014;9(10):e109885 Authors: Ye Z, Zheng Y, Li B, Borrusch MS, Storms R, Walton JD

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Fungal genomics.

Author(s): Tsang A

Brief Funct Genomics. 2014 Nov;13(6):421-3 Authors: Tsang A PMID: 25411199 [PubMed - indexed for MEDLINE]

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Genetic Structure, Diversity and Long Term Viability of a Medicinal Plant, Nothapodytes nimmoniana Graham. (Icacinaceae), in Protected and Non-Protected Areas in the Western Ghats Biodiversity Hotspot.

Author(s): Shivaprakash KN, Ramesha BT, Uma Shaanker R, Dayanandan S, Ravikanth G

PLoS One. 2014;9(12):e112769 Authors: Shivaprakash KN, Ramesha BT, Uma Shaanker R, Dayanandan S, Ravikanth G

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Genetic relatedness among indigenous rice varieties in the Eastern Himalayan region based on nucleotide sequences of the Waxy gene.

Author(s): Choudhury BI, Khan ML, Dayanandan S

BMC Res Notes. 2014 Dec 29;7:953 Authors: Choudhury BI, Khan ML, Dayanandan S

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Mycothermus thermophilus gen. et comb. nov., a new home for the itinerant thermophile Scytalidium thermophilum (Torula thermophila).

Author(s): Natvig DO, Taylor JW, Tsang A, Hutchinson MI, Powell AJ

Mycologia. 2015 Mar-Apr;107(2):319-27 Authors: Natvig DO, Taylor JW, Tsang A, Hutchinson MI, Powell AJ

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Machine learning for biomedical literature triage.

Author(s): Almeida H, Meurs MJ, Kosseim L, Butler G, Tsang A

PLoS One. 2014;9(12):e115892 Authors: Almeida H, Meurs MJ, Kosseim L, Butler G, Tsang A

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mycoCLAP, the database for characterized lignocellulose-active proteins of fungal origin: resource and text mining curation support.

Author(s): Strasser K, McDonnell E, Nyaga C, Wu M, Wu S, Almeida H, Meurs MJ, Kosseim L, Powlowski J, Butler G, Tsang A

Database (Oxford). 2015;2015: Authors: Strasser K, McDonnell E, Nyaga C, Wu M, Wu S, Almeida H, Meurs MJ, Kosseim L, Powlowski J, Butler G, Tsang A

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tRNAGlu increases the affinity of glutamyl-tRNA synthetase for its inhibitor glutamyl-sulfamoyl-adenosine, an analogue of the aminoacylation reaction intermediate glutamyl-AMP: mechanistic and evolutionary implications.

Author(s): Blais SP, Kornblatt JA, Barbeau X, Bonnaure G, Lagüe P, Chênevert R, Lapointe J

PLoS One. 2015;10(4):e0121043 Authors: Blais SP, Kornblatt JA, Barbeau X, Bonnaure G, Lagüe P, Chênevert R, Lapointe J

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Deconstructing the genetic basis of spent sulphite liquor tolerance using deep sequencing of genome-shuffled yeast.

Author(s): Pinel D, Colatriano D, Jiang H, Lee H, Martin VJ

Biotechnol Biofuels. 2015;8:53 Authors: Pinel D, Colatriano D, Jiang H, Lee H, Martin VJ

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Translational regulation in chloroplasts for development and homeostasis.

Author(s): Sun Y, Zerges W

Biochim Biophys Acta. 2015 Sep;1847(9):809-20 Authors: Sun Y, Zerges W

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Metabolic engineering of a tyrosine-overproducing yeast platform using targeted metabolomics.

Author(s): Gold ND, Gowen CM, Lussier FX, Cautha SC, Mahadevan R, Martin VJ

Microb Cell Fact. 2015 May 28;14:73 Authors: Gold ND, Gowen CM, Lussier FX, Cautha SC, Mahadevan R, Martin VJ

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Improvement in Saccharification Yield of Mixed Rumen Enzymes by Identification of Recalcitrant Cell Wall Constituents Using Enzyme Fingerprinting.

Author(s): Badhan A, Wang YX, Gruninger R, Patton D, Powlowski J, Tsang A, McAllister TA

Biomed Res Int. 2015;2015:562952 Authors: Badhan A, Wang YX, Gruninger R, Patton D, Powlowski J, Tsang A, McAllister TA

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Closely related fungi employ diverse enzymatic strategies to degrade plant biomass.

Author(s): Benoit I, Culleton H, Zhou M, DiFalco M, Aguilar-Osorio G, Battaglia E, Bouzid O, Brouwer CPJM, El-Bushari HBO, Coutinho PM, Gruben BS, Hild...

Biotechnol Biofuels. 2015;8:107 Authors: Benoit I, Culleton H, Zhou M, DiFalco M, Aguilar-Osorio G, Battaglia E, Bouzid O, Brouwer CPJM, El-Bushari HBO, Coutinho PM, Gruben BS, Hildén KS, Hou...

Article GUID: 26236396

A Highly Effective Component Vaccine against Nontyphoidal Salmonella enterica Infections.

Author(s): Ferreira RB, Valdez Y, Coombes BK, Sad S, Gouw JW, Brown EM, Li Y, Grassl GA, Antunes LC, Gill N, Truong M, Scholz R, Reynolds LA, Krishnan ...

MBio. 2015 Sep 22;6(5):e01421-15 Authors: Ferreira RB, Valdez Y, Coombes BK, Sad S, Gouw JW, Brown EM, Li Y, Grassl GA, Antunes LC, Gill N, Truong M, Scholz R, Reynolds LA, Krishnan L, Zafer AA, S...

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Localized control of oxidized RNA.

Author(s): Zhan Y, Dhaliwal JS, Adjibade P, Uniacke J, Mazroui R, Zerges W

J Cell Sci. 2015 Nov 15;128(22):4210-9 Authors: Zhan Y, Dhaliwal JS, Adjibade P, Uniacke J, Mazroui R, Zerges W

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Malbranchea cinnamomea: A thermophilic fungal source of catalytically efficient lignocellulolytic glycosyl hydrolases and metal dependent enzymes.

Author(s): Mahajan C, Basotra N, Singh S, Di Falco M, Tsang A, Chadha BS

Bioresour Technol. 2016 Jan;200:55-63 Authors: Mahajan C, Basotra N, Singh S, Di Falco M, Tsang A, Chadha BS

Article GUID: 26476165

Genetics of mating in members of the Chaetomiaceae as revealed by experimental and genomic characterization of reproduction in Myceliophthora heterothallica.

Author(s): Hutchinson MI, Powell AJ, Tsang A, O'Toole N, Berka RM, Barry K, Grigoriev IV, Natvig DO

Fungal Genet Biol. 2016 Jan;86:9-19 Authors: Hutchinson MI, Powell AJ, Tsang A, O'Toole N, Berka RM, Barry K, Grigoriev IV, Natvig DO

Article GUID: 26608618

Directed evolution of a fungal β-glucosidase in Saccharomyces cerevisiae.

Author(s): Larue K, Melgar M, Martin VJ

Biotechnol Biofuels. 2016;9:52 Authors: Larue K, Melgar M, Martin VJ

Article GUID: 26949413

Engineering of a Nepetalactol-Producing Platform Strain of Saccharomyces cerevisiae for the Production of Plant Seco-Iridoids.

Author(s): Campbell A, Bauchart P, Gold ND, Zhu Y, De Luca V, Martin VJ

ACS Synth Biol. 2016 05 20;5(5):405-14 Authors: Campbell A, Bauchart P, Gold ND, Zhu Y, De Luca V, Martin VJ

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Secretion of small proteins is species-specific within Aspergillus sp.

Author(s): Valette N, Benoit-Gelber I, Falco MD, Wiebenga A, de Vries RP, Gelhaye E, Morel-Rouhier M

Microb Biotechnol. 2017 03;10(2):323-329 Authors: Valette N, Benoit-Gelber I, Falco MD, Wiebenga A, de Vries RP, Gelhaye E, Morel-Rouhier M

Article GUID: 27153937

A set of isogenic auxotrophic strains for constructing multiple gene deletion mutants and parasexual crossings in Aspergillus niger.

Author(s): Niu J, Arentshorst M, Seelinger F, Ram AF, Ouedraogo JP

Arch Microbiol. 2016 Nov;198(9):861-8 Authors: Niu J, Arentshorst M, Seelinger F, Ram AF, Ouedraogo JP

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Evaluation of secretome of highly efficient lignocellulolytic Penicillium sp. Dal 5 isolated from rhizosphere of conifers.

Author(s): Rai R, Kaur B, Singh S, Di Falco M, Tsang A, Chadha BS

Bioresour Technol. 2016 Sep;216:958-67 Authors: Rai R, Kaur B, Singh S, Di Falco M, Tsang A, Chadha BS

Article GUID: 27341464

The RNA Structure of cis-acting Translational Elements of the Chloroplast psbC mRNA in Chlamydomonas reinhardtii.

Author(s): Rahim MM, Vigneault F, Zerges W

Front Plant Sci. 2016;7:828 Authors: Rahim MM, Vigneault F, Zerges W

Article GUID: 27379123

Reconstituting Plant Secondary Metabolism in Saccharomyces cerevisiae for Production of High-Value Benzylisoquinoline Alkaloids.

Author(s): Pyne ME, Narcross L, Fossati E, Bourgeois L, Burton E, Gold ND, Martin VJ

Methods Enzymol. 2016;575:195-224 Authors: Pyne ME, Narcross L, Fossati E, Bourgeois L, Burton E, Gold ND, Martin VJ

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An Adaptive Defect Weighted Sampling Algorithm to Design Pseudoknotted RNA Secondary Structures.

Author(s): Zandi K, Butler G, Kharma N

Front Genet. 2016;7:129 Authors: Zandi K, Butler G, Kharma N

Article GUID: 27499762

Mycothermus thermophilus (Syn. Scytalidium thermophilum): Repertoire of a diverse array of efficient cellulases and hemicellulases in the secretome revealed

Author(s): Neha Basotra

Mycothermus thermophilus (Syn. Scytalidium thermophilum/Humicola insolens), a thermophilic fungus, is being reported to produce appreciable titers of cellulases and hemicellulases during shake flask culturing on cellulose/wheat-bran/rice straw based product...

Article GUID: 27744242

The molecular response of the white-rot fungus Dichomitus squalens to wood and non-woody biomass as examined by transcriptome and exoproteome analyses.

Author(s): Rytioja J, Hildén K, Di Falco M, Zhou M, Aguilar-Pontes MV, Sietiö OM, Tsang A, de Vries RP, Mäkelä MR

Environ Microbiol. 2017 03;19(3):1237-1250 Authors: Rytioja J, Hildén K, Di Falco M, Zhou M, Aguilar-Pontes MV, Sietiö OM, Tsang A, de Vries RP, Mäkelä MR

Article GUID: 28028889

An Evolutionarily Conserved Transcriptional Activator-Repressor Module Controls Expression of Genes for D-Galacturonic Acid Utilization in Aspergillus niger.

Author(s): Niu J, Alazi E, Reid ID, Arentshorst M, Punt PJ, Visser J, Tsang A, Ram AF

Genetics. 2017 01;205(1):169-183 Authors: Niu J, Alazi E, Reid ID, Arentshorst M, Punt PJ, Visser J, Tsang A, Ram AF

Article GUID: 28049705

Identification of Genes Involved in the Degradation of Lignocellulose Using Comparative Transcriptomics.

Author(s): Gruninger RJ, Reid I, Forster RJ, Tsang A, McAllister TA

Methods Mol Biol. 2017;1588:279-298 Authors: Gruninger RJ, Reid I, Forster RJ, Tsang A, McAllister TA

Article GUID: 28417376

Isolation and Preparation of Extracellular Proteins from Lignocellulose Degrading Fungi for Comparative Proteomic Studies Using Mass Spectrometry

Author(s): Robert J Gruninger

Fungi utilize a unique mechanism of nutrient acquisition involving extracellular digestion. To understand the biology of these microbes, it is important to identify and characterize the function of proteins that are secreted and involved in this process. Ma...

Article GUID: 28417377

The pathway intermediate 2-keto-3-deoxy-L-galactonate mediates the induction of genes involved in D-galacturonic acid utilization in Aspergillus niger.

Author(s): Alazi E, Khosravi C, Homan TG, du Pré S, Arentshorst M, Di Falco M, Pham TTM, Peng M, Aguilar-Pontes MV, Visser J, Tsang A, de Vries RP, Ram AFJ

FEBS Lett. 2017 05;591(10):1408-1418 Authors: Alazi E, Khosravi C, Homan TG, du Pré S, Arentshorst M, Di Falco M, Pham TTM, Peng M, Aguilar-Pontes MV, Visser J, Tsang A, de Vries RP, Ram AFJ

Article GUID: 28417461

Discovery and characterization of family 39 glycoside hydrolases from rumen anaerobic fungi with polyspecific activity on rare arabinosyl substrates.

Author(s): Jones DR, Uddin MS, Gruninger RJ, Pham TTM, Thomas D, Boraston AB, Briggs J, Pluvinage B, McAllister TA, Forster RJ, Tsang A, Selinger LB, Abbott DW

J Biol Chem. 2017 07 28;292(30):12606-12620 Authors: Jones DR, Uddin MS, Gruninger RJ, Pham TTM, Thomas D, Boraston AB, Briggs J, Pluvinage B, McAllister TA, Forster RJ, Tsang A, Selinger LB, Abbott DW

Article GUID: 28588026

Structure-Guided Directed Evolution of Glycosidases: A Case Study in Engineering a Blood Group Antigen-Cleaving Enzyme.

Author(s): Kwan DH

Methods Enzymol. 2017;597:25-53 Authors: Kwan DH

Article GUID: 28935105

Expression-based clustering of CAZyme-encoding genes of Aspergillus niger.

Author(s): Gruben BS, Mäkelä MR, Kowalczyk JE, Zhou M, Benoit-Gelber I, De Vries RP

BMC Genomics. 2017 Nov 23;18(1):900 Authors: Gruben BS, Mäkelä MR, Kowalczyk JE, Zhou M, Benoit-Gelber I, De Vries RP

Article GUID: 29169319

Expression of catalytically efficient xylanases from thermophilic fungus Malbranchea cinnamomea for synergistically enhancing hydrolysis of lignocellulosics.

Author(s): Basotra N, Joshi S, Satyanarayana T, Pati PK, Tsang A, Chadha BS

Int J Biol Macromol. 2018 Mar;108:185-192 Authors: Basotra N, Joshi S, Satyanarayana T, Pati PK, Tsang A, Chadha BS

Article GUID: 29174359

Pyrenoid functions revealed by proteomics in Chlamydomonas reinhardtii

Author(s): Zhan Y; Marchand CH; Maes A; Mauries A; Sun Y; Dhaliwal JS; Uniacke J; Arragain S; Jiang H; Gold ND; Martin VJJ; Lemaire SD; Zerges W;...

Organelles are intracellular compartments which are themselves compartmentalized. Biogenic and metabolic processes are localized to specialized domains or microcompartments to enhance their efficie...

Article GUID: 29481573

Identification of novel enzymes to enhance the ruminal digestion of barley straw

Author(s): Badhan A; Ribeiro GO; Jones DR; Wang Y; Abbott DW; Di Falco M; Tsang A; McAllister TA;

Crude enzyme extracts typically contain a broad spectrum of enzyme activities, most of which are redundant to those naturally produced by the rumen microbiome. Identification of enzyme activities that are synergistic to those produced by the rumen microbiom...

Article GUID: 29621684

Saccharification efficiencies of multi-enzyme complexes produced by aerobic fungi.

Author(s): Badhan A, Huang J, Wang Y, Abbott DW, Di Falco M, Tsang A, McAllister T

N Biotechnol. 2018 Nov 25;46:1-6 Authors: Badhan A, Huang J, Wang Y, Abbott DW, Di Falco M, Tsang A, McAllister T

Article GUID: 29803771

Introduction: Overview of Fungal Genomics.

Author(s): de Vries RP, Grigoriev IV, Tsang A

Methods Mol Biol. 2018;1775:1-7 Authors: de Vries RP, Grigoriev IV, Tsang A

Article GUID: 29876804

Fungal Genomic DNA Extraction Methods for Rapid Genotyping and Genome Sequencing.

Author(s): Bellemare A, John T, Marqueteau S

Methods Mol Biol. 2018;1775:11-20 Authors: Bellemare A, John T, Marqueteau S

Article GUID: 29876805

Mass Spectrometry-Based Proteomics

Author(s): Marcos Rafael Di Falco

Proteomics is the large-scale analysis of proteins rendered possible by modern mass spectrometry analysis methods capable of identifying thousands of peptides/proteins in a fast high-throughput manner. Here I describe protocols for the preparation of fungal...

Article GUID: 29876812

Manual Gene Curation and Functional Annotation.

Author(s): McDonnell E, Strasser K, Tsang A

Methods Mol Biol. 2018;1775:185-208 Authors: McDonnell E, Strasser K, Tsang A

Article GUID: 29876819

Evaluating Programs for Predicting Genes and Transcripts with RNA-Seq Support in Fungal Genomes.

Author(s): Reid I

Methods Mol Biol. 2018;1775:209-227 Authors: Reid I

Article GUID: 29876820

The effect of different divalent cations on the kinetics and fidelity of Bacillus stearothermophilus DNA polymerase.

Author(s): Vashishtha AK, Konigsberg WH

AIMS Biophys. 2018;5(2):125-143 Authors: Vashishtha AK, Konigsberg WH

Article GUID: 29888334

New recombinant fibrolytic enzymes for improved in vitro ruminal fiber degradability of barley straw.

Author(s): Ribeiro GO, Badhan A, Huang J, Beauchemin KA, Yang W, Wang Y, Tsang A, McAllister TA

J Anim Sci. 2018 Jul 20;: Authors: Ribeiro GO, Badhan A, Huang J, Beauchemin KA, Yang W, Wang Y, Tsang A, McAllister TA

Article GUID: 30053012

Application of Transcriptomics to Compare the Carbohydrate Active Enzymes That Are Expressed by Diverse Genera of Anaerobic Fungi to Degrade Plant Cell Wall Carbohydrates.

Author(s): Gruninger RJ, Nguyen TTM, Reid ID, Yanke JL, Wang P, Abbott DW, Tsang A, McAllister T

Front Microbiol. 2018;9:1581 Authors: Gruninger RJ, Nguyen TTM, Reid ID, Yanke JL, Wang P, Abbott DW, Tsang A, McAllister T

Article GUID: 30061875

Efficient genome editing using tRNA promoter-driven CRISPR/Cas9 gRNA in Aspergillus niger.

Author(s): Song L, Ouedraogo JP, Kolbusz M, Nguyen TTM, Tsang A

PLoS One. 2018;13(8):e0202868 Authors: Song L, Ouedraogo JP, Kolbusz M, Nguyen TTM, Tsang A

Article GUID: 30142205

W361R mutation in GaaR, the regulator of D-galacturonic acid-responsive genes, leads to constitutive production of pectinases in Aspergillus niger.

Author(s): Alazi E, Niu J, Otto SB, Arentshorst M, Pham TTM, Tsang A, Ram AFJ

Microbiologyopen. 2019 May;8(5):e00732 Authors: Alazi E, Niu J, Otto SB, Arentshorst M, Pham TTM, Tsang A, Ram AFJ

Article GUID: 30298571

Investigation of inter- and intraspecies variation through genome sequencing of Aspergillus section Nigri.

Author(s): Vesth TC, Nybo JL, Theobald S, Frisvad JC, Larsen TO, Nielsen KF, Hoof JB, Brandl J, Salamov A, Riley R, Gladden JM, Phatale P, Nielsen MT, ...

Nat Genet. 2018 12;50(12):1688-1695 Authors: Vesth TC, Nybo JL, Theobald S, Frisvad JC, Larsen TO, Nielsen KF, Hoof JB, Brandl J, Salamov A, Riley R, Gladden JM, Phatale P, Nielsen MT, Lyhne EK, K...

Article GUID: 30349117

Determinants of selection in yeast evolved by genome shuffling.

Author(s): Biot-Pelletier D, Pinel D, Larue K, Martin VJJ

Biotechnol Biofuels. 2018;11:282 Authors: Biot-Pelletier D, Pinel D, Larue K, Martin VJJ

Article GUID: 30356826

The obligate alkalophilic soda-lake fungus Sodiomyces alkalinus has shifted to a protein diet.

Author(s): Grum-Grzhimaylo AA, Falkoski DL, van den Heuvel J, Valero-Jiménez CA, Min B, Choi IG, Lipzen A, Daum CG, Aanen DK, Tsang A, Henrissat B, Bil...

Mol Ecol. 2018 12;27(23):4808-4819 Authors: Grum-Grzhimaylo AA, Falkoski DL, van den Heuvel J, Valero-Jiménez CA, Min B, Choi IG, Lipzen A, Daum CG, Aanen DK, Tsang A, Henrissat B, Bilanenko ...

Article GUID: 30368956

The gold-standard genome of Aspergillus niger NRRL 3 enables a detailed view of the diversity of sugar catabolism in fungi.

Author(s): Aguilar-Pontes MV, Brandl J, McDonnell E, Strasser K, Nguyen TTM, Riley R, Mondo S, Salamov A, Nybo JL, Vesth TC, Grigoriev IV, Andersen MR,...

Stud Mycol. 2018 Sep;91:61-78 Authors: Aguilar-Pontes MV, Brandl J, McDonnell E, Strasser K, Nguyen TTM, Riley R, Mondo S, Salamov A, Nybo JL, Vesth TC, Grigoriev IV, Andersen MR, Tsang A, de Vrie...

Article GUID: 30425417

A Combinatorial Approach To Study Cytochrome P450 Enzymes for De Novo Production of Steviol Glucosides in Baker's Yeast.

Author(s): Gold ND, Fossati E, Hansen CC, DiFalco M, Douchin V, Martin VJJ

ACS Synth Biol. 2018 Dec 21;7(12):2918-2929 Authors: Gold ND, Fossati E, Hansen CC, DiFalco M, Douchin V, Martin VJJ

Article GUID: 30474973

Genomic and exoproteomic diversity in plant biomass degradation approaches among Aspergilli

Author(s): Mäkelä MR; DiFalco M; McDonnell E; Nguyen TTM; Wiebenga A; Hildén K; Peng M; Grigoriev IV; Tsang A; de Vries RP;...

We classified the genes encoding carbohydrate-active enzymes (CAZymes) in 17 sequenced genomes representing 16 evolutionarily diverse Aspergillus species. We performed a phylogenetic analysis of th...

Article GUID: 30487660

Engineering Plant Secondary Metabolism in Microbial Systems.

Author(s): Pyne ME, Narcross L, Martin VJJ

Plant Physiol. 2019 03;179(3):844-861 Authors: Pyne ME, Narcross L, Martin VJJ PMID: 30643013 [PubMed - indexed for MEDLINE]

Article GUID: 30643013

Thermostable xylanases from thermophilic fungi and bacteria: Current perspective.

Author(s): Chadha BS, Kaur B, Basotra N, Tsang A, Pandey A

Bioresour Technol. 2019 Apr;277:195-203 Authors: Chadha BS, Kaur B, Basotra N, Tsang A, Pandey A

Article GUID: 30679061

The presence of trace components significantly broadens the molecular response of Aspergillus niger to guar gum.

Author(s): Coconi Linares N, Di Falco M, Benoit-Gelber I, Gruben BS, Peng M, Tsang A, Mäkelä MR, de Vries RP

N Biotechnol. 2019 Jul 25;51:57-66 Authors: Coconi Linares N, Di Falco M, Benoit-Gelber I, Gruben BS, Peng M, Tsang A, Mäkelä MR, de Vries RP

Article GUID: 30797054

Origin and evolution of the genus Piper in Peninsular India.

Author(s): Sen S, Dayanandan S, Davis T, Ganesan R, Jagadish MR, Mathew PJ, Ravikanth G

Origin and evolution of the genus Piper in Peninsular India.

Mol Phylogenet Evol. 2019 May 25;138:102-113

Authors: Sen S, Dayanandan S, Davis T, Ganesan R, Jagadish MR, Mathew PJ, Ravikanth G

Abstract
The evolution of Peni...

Article GUID: 31132521

Phylogenetic Analysis of Protein Family.

Author(s): Song L, Wu S, Tsang A

Phylogenetic Analysis of Protein Family.

Methods Mol Biol. 2018;1775:267-275

Authors: Song L, Wu S, Tsang A

Abstract
With the number of sequenced genomes increasing rapidly, it is impractical to perform functional and stru...

Article GUID: 29876824