Keyword search (3,138 papers available)


A Pilot Randomized Trial of Combined Cognitive-Behavioral Therapy and Exercise Training Versus Exercise Training Alone for the Management of Chronic Insomnia in Obstructive Sleep Apnea

Author(s): Cammalleri A; Perrault AA; Hillcoat A; Carrese-Chacra E; Tarelli L; Patel R; Baltzan M; Chouchou F; Dang-Vu TT; Gouin JP; Pepin V;...

Insomnia treatment among individuals with comorbid insomnia and obstructive sleep apnea is suboptimal. In a pilot randomized controlled trial, 19 individuals with comorbid insomnia and obstructive ...

Article GUID: 38663849
Co-Development of Three Dietary Indices to Facilitate Dietary Intake Assessment of Pediatric Crohn's Disease Patients

Author(s): Harvey A.; Mannette J.; Sigall-Boneh R.; Macintyre B.; Parrott M.; Cahill L.; Connors J.; Otley A.; van Limbergen J.; Grant S.;...

Literature on dietary behaviours of the pediatric Crohn's Disease (CD) population and the relationship between dietary intake and CD activity is limited. Three dietary indices were developed an...

Article GUID: 38634640
Paraspinal Muscle Changes in Individuals with and without Chronic Low Back Pain over a 4-Month Period: A Longitudinal MRI Study

Author(s): Anstruther M; Sean M; Tétreault P; Fortin M;

Background and Objectives: Previous research has shown associations between atrophy and fatty infiltration of the lumbar paraspinal musculature and low back pain (LBP). However, few studies have examined longitudinal changes in healthy controls and individu...

Article GUID: 38541216
MVComp toolbox: MultiVariate Comparisons of brain MRI features accounting for common information across metrics

Author(s): Tremblay SA; Alasmar Z; Pirhadi A; Carbonell F; Iturria-Medina Y; Gauthier CJ; Steele CJ;

Multivariate approaches have recently gained in popularity to address the physiological unspecificity of neuroimaging metrics and to better characterize the complexity of biological processes underlying behavior. However, commonly used approaches are biased...

Article GUID: 38463982
The assessment of paraspinal muscle epimuscular fat in participants with and without low back pain: A case-control study

Author(s): Rosenstein B; Burdick J; Roussac A; Rye M; Naghdi N; Valentin S; Licka T; Sean M; Tétreault P; Elliott J; Fortin M;...

It remains unclear whether paraspinal muscle fatty infiltration in low back pain (LBP) is i) solely intramuscular, ii) is lying outside the epimysium between the muscle and fascial plane (epimuscul...

Article GUID: 38280825
Consistency of electrical source imaging in presurgical evaluation of epilepsy across different vigilance states

Author(s): Avigdor T; Abdallah C; Afnan J; Cai Z; Rammal S; Grova C; Frauscher B;

Objective: The use of electrical source imaging (ESI) in assessing the source of interictal epileptic discharges (IEDs) is gaining increasing popularity in presurgical work-up of patients with drug-resistant focal epilepsy. While vigilance affects the abili...

Article GUID: 38217279
NSF evaluation of gadolinium biodistribution in renally impaired rats: Using novel metabolic Gd2O3 nanoparticles coated with β-cyclodextrin (Gd2O3@PCD) in MR molecular imaging

Author(s): Ashouri H; Alam NR; Khoobi M; Haghgoo S; Rasouli Z; Gholami M;

The use of conventional gadolinium(Gd)-based contrast agents in magnetic resonance imaging (MRI) poses a significant risk of Nephrogenic Systemic Fibrosis (NSF) syndrome in patients with impaired renal function (grades 4 and 5). To address this issue, a new...

Article GUID: 38215955
Decreased long-range temporal correlations in the resting-state functional magentic resonance imaging blood-oxygen-level-dependent signal reflect motor sequence learning up to 2 weeks following training

Author(s): Jäger AP; Bailey A; Huntenburg JM; Tardif CL; Villringer A; Gauthier CJ; Nikulin V; Bazin PL; Steele CJ;...

Decreased long-range temporal correlations (LRTC) in brain signals can be used to measure cognitive effort during task execution. Here, we examined how learning a motor sequence affects long-range ...

Article GUID: 38124341
Effect of aquatic exercise versus standard care on paraspinal and gluteal muscles morphology in individuals with chronic low back pain: a randomized controlled trial protocol

Author(s): Rosenstein B; Montpetit C; Vaillancourt N; Dover G; Khalini-Mahani N; Weiss C; Papula LA; Melek A; Fortin M;...

Background: Low back pain (LBP) is one of the most disabling diseases and a major health issue. Despite the evidence of a link between paraspinal and gluteal muscle dysfunction and LBP, it is unkno...

Article GUID: 38110922
Title:Brain PET Imaging in Small Animals: Tracer Formulation, Data Acquisition, Image Reconstruction, and Data Analysis
Authors:Bdair H,  Kang MS,  Ottoy J,  Aliaga A,  Kunach P,  Singleton TA,  Blinder S,  Soucy JP,  Leyton M,  Rosa-Neto P,  Kostikov A, 
Link:https://pubmed.ncbi.nlm.nih.gov/38006502/
DOI:10.1007/978-1-0716-3499-8_16
Category:
PMID:38006502
Dept Affiliation: PERFORM
1 Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada.
2 Department of Psychiatry, McGill University, Montreal, QC, Canada.
3 McConnell Brain Imaging Centre, Montreal Neurological Institute-Hospital (The Neuro), McGill University, Montreal, QC, Canada.
4 Translational Neuroimaging Laboratory, Research Centre for Studies in Aging, Douglas Research Institute, McGill University, Montreal, QC, Canada.
5 LC Campbell Cognitive Neurology Unit, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada.
6 PERFORM Centre, Concordia University, Montreal, QC, Canada.
7 Department of Psychology, McGill University, Montreal, QC, Canada.
8 Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, QC, Canada.
9 Department of Neurology and Neurosurgery, Mc

Description:

Positron emission tomography (PET) is a noninvasive functional imaging modality that involves in vivo detection of spatiotemporal changes in the binding of radioactive pharmaceuticals (a.k.a. PET tracers) to their target sites in different organs. The development of new PET tracers commonly involves their preclinical evaluation in small rodents. Moreover, laboratory animal PET research is now being used with progressively greater frequency to complement human PET studies, to investigate in greater depth the underlying pathophysiology of human diseases, and to monitor the efficiency of novel therapeutic interventions. Here we describe the steps toward a successful small animal PET study, from tracer formulation and image acquisition to data reconstruction and analysis of the acquired scans, with a particular focus on its utility for the brain.