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Author(s): Barbaux L; Cross NE; Perrault AA; Es-Sounni M; Desrosiers C; Clerc D; Andriamampionona F; Lussier D; Tannenbaum C; Guimond A; Grenier S; Gou...
Objectives: Our objective was to assess the effect of cognitive-behavioral therapy for insomnia (CBTi) on subjective and objective sleep quality (including sleep spindles) and cogn...
Article GUID: 41092866
Author(s): Phelps J; Singh M; McCreary CR; Dallaire-Théroux C; Stein RG; Potvin-Jutras Z; Guan DX; Wu JD; Metz A; Smith EE;...
Cerebral small vessel disease (CSVD) can manifest as brain lesions visible on magnetic resonance imaging, including white matter hyperintensities (WMH), cerebral microbleeds (CMB), perivascular spa...
Article GUID: 41080650
Author(s): Nutter S; Waugh R; McEachran E; Toor A; Shelley J; Alberga AS; Forhan M; Kirk SF; Nagpal TS; Patton I; Ramos Salas X; Russell-Mayhew S;...
Weight stigma negatively impacts people with higher weights across the lifespan as well as social contexts and can lead to weight discrimination. As weight is not a protected identity in Canadian h...
Article GUID: 41029703
Author(s): Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Fajardo Valdez A; Mohammedi...
The PResymptomatic EValuation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) is an investigator-driven study that was created in 2011 and enrolled cognitively normal o...
Article GUID: 41020412
Author(s): MacNeil S; da Estrela C; Caldwell W; Gouin JP;
Objective: A parent's ability to self-regulate influences parenting practices. Child-related stressors may deplete parent's self-regulatory capacities. However, this effect may be moderated by the marital context within which stressful parent-child ...
Article GUID: 40972822
Author(s): Pieruccini-Faria F; Son S; Zou G; Almeida QJ; Middleton LE; Bray NW; Lussier M; Shoemaker JK; Speechley M; Liu-Ambrose T; Burhan AM; Camicio...
Background: Older adults with mild cognitive impairment (MCI) have a higher risk of gait impairments and falls; yet, the effects of multimodal interventions, including combinations of exercises wit...
Article GUID: 40966614
Author(s): Jäger AP; Steele CJ; Dreyer FR; Osterloh MR; Sadlon A; Nikulin V; Mohr B; Pulvermüller F;
Background: Intensive language-action therapy treats language deficits and depressive symptoms in chronic poststroke aphasia, yet the underlying neural mechanisms remain underexplored. Long-range temporal correlations (LRTCs) in blood oxygenation level-depe...
Article GUID: 40927858
Author(s): Saputra ST; Van Hulst A; Henderson M; Brugiapaglia S; Faustini C; Kakinami L;
Background: A dual-energy x-ray absorptiometry (DXA)-derived phenotype classification based on fat mass and muscle mass has been developed for adults. We extended this to a paediatric population. Methods: Children's (= 17 years) DXA data in NHANES (n =...
Article GUID: 40878792
Author(s): Tremblay SA; Potvin-Jutras Z; Sabra D; Rezaei A; Sanami S; Gagnon C; Intzandt B; Mainville-Berthiaume A; Wright L; Leppert IR; Tardif CL; St...
Patients with coronary artery disease (CAD) face an increased risk of cognitive impairment, dementia, and stroke. While white matter (WM) lesions are frequently reported in patients with CAD, the e...
Article GUID: 40829939
| Title: | Development and Application of Children s Sex- and Age-Specific Fat-Mass and Muscle-Mass Reference Curves From Dual-Energy X-Ray Absorptiometry Data for Predicting Cardiometabolic Risk |
| Authors: | Saputra ST, Van Hulst A, Henderson M, Brugiapaglia S, Faustini C, Kakinami L, |
| Link: | https://pubmed.ncbi.nlm.nih.gov/40878792/ |
| DOI: | 10.1111/ijpo.70051 |
| Category: | |
| PMID: | 40878792 |
| Dept Affiliation: | SOH
1 Department of Mathematics and Statistics, Concordia University, Quebec, Canada. 2 Ingram School of Nursing, McGill University, Quebec, Canada. 3 Centre de Recherche CHU Sainte-Justine, Université de Montréal, Quebec, Canada. 4 Department of Pediatrics, Université de Montréal, Quebec, Canada. 5 School of Public Health, Department of Social and Preventive Medicine, Université de Montréal, Montréal, Quebec, Canada. 6 School of Health, Concordia University, Quebec, Canada. |
Description: |
Background: A dual-energy x-ray absorptiometry (DXA)-derived phenotype classification based on fat mass and muscle mass has been developed for adults. We extended this to a paediatric population. Methods: Children's (= 17 years) DXA data in NHANES (n = 6120) were used to generate sex- and age-specific deciles of appendicular skeletal muscle mass index and fat mass index with the Lambda Mu Sigma method. Four phenotypes (high [H] or low [L], adiposity [A] and muscle mass [M]: HA-HM, HA-LM, LA-HM, LA-LM) were identified based on being above/below the median compared to same-sex and same-age peers. These reference curves were applied to the QUALITY cohort (n = 630, 8-10 years of age in 2005) to assess whether the phenotypes correctly identified cardiometabolic risk at baseline, follow-up (2008-2010), and their longitudinal changes. Multiple linear regression models were adjusted for age, sex, and Tanner's stage. Results: Compared to the LA-HM reference group, the HA-HM phenotype was associated with less favourable HDL, triglycerides, and HOMA-IR at baseline and first follow-up, but not in their changes. The HA-LM phenotype was associated with less favourable HOMA-IR at baseline and first follow-up. Conclusions: Results suggest that phenotypes based on fat and muscle mass may have clinical utility in children and should be further investigated. |
