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The more they hear the more they learn? Using data from bilinguals to test models of early lexical development

Author(s): Sander-Montant A; López Pérez M; Byers-Heinlein K;

Children have an early ability to learn and comprehend words, a skill that develops as they age. A critical question remains regarding what drives this development. Maturation-based theories emphasise cognitive maturity as a driver of comprehension, while accumulator theories emphasise children's accumulation of language experience over time. In this ...

Article GUID: 37402336


Preparation, characteristics, and performance of the microemulsion system in the removal of oil from beach sand

Author(s): Bi H; Mulligan CN; Lee K; An C; Wen J; Yang X; Lyu L; Qu Z;

Oil deposited on shoreline substrates has serious adverse effects on the coastal environment and can persist for a long time. In this study, a green and effective microemulsion (ME) derived from vegetable oil was developed as a washing fluid to remove stranded oil from beach sand. The pseudo-ternary phase diagrams of the castor oil/water (without or witho ...

Article GUID: 37399736


Functional analysis of the protocatechuate branch of the β-ketoadipate pathway in Aspergillus niger

Author(s): Sgro M; Chow N; Olyaei F; Arentshorst M; Geoffrion N; Ram AFJ; Powlowski J; Tsang A;

Bacteria and fungi catabolize plant-derived aromatic compounds by funneling into one of seven dihydroxylated aromatic intermediates, which then undergo ring fission and conversion to TCA cycle intermediates. Two of these intermediates, protocatechuic acid and catechol, converge on ß-ketoadipate which is further cleaved to succinyl-CoA and acetyl-CoA. Thes ...

Article GUID: 37399977


User-friendly and ultra-stable all-inclusive gold tablets for cysteamine detection

Author(s): Al-Kassawneh M; Sadiq Z; Jahanshahi-Anbuhi S;

To date, a range of nanozymes has been reported for their enzyme-mimicking catalytic activity such as solution-based sensors. However, in remote areas, the need for portable, cost-effective, and one-pot prepared sensors is obvious. In this study, we report the development of a highly stable and sensitive gold tablet-based sensor for cysteamine quantificat ...

Article GUID: 37397283


Blocking μ-opioid receptors attenuates reinstatement of responding to an alcohol-predictive conditioned stimulus through actions in the ventral hippocampus

Author(s): Mandy Rita LeCocq

The µ-opioid system is involved in the reinstatement of responding that is immediately evoked by alcohol-predictive cues. The extent of its involvement in reinstatement observed in a new model that evaluates the delayed effects of re-exposure to alcohol, however, is unclear. The current study investigated the role of µ-opioid receptors (MORs) in the delay ...

Article GUID: 37393348


Class imbalance should not throw you off balance: Choosing the right classifiers and performance metrics for brain decoding with imbalanced data

Author(s): Thölke P; Mantilla-Ramos YJ; Abdelhedi H; Maschke C; Dehgan A; Harel Y; Kemtur A; Mekki Berrada L; Sahraoui M; Young T; Bellemare Pépin A; El Khantour C; Landry M; Pascarella A; Hadid V; Combrisson E; O' Byrne J; Jerbi K;

Machine learning (ML) is increasingly used in cognitive, computational and clinical neuroscience. The reliable and efficient application of ML requires a sound understanding of its subtleties and limitations. Training ML models on datasets with imbalanced classes is a particularly common problem, ...

Article GUID: 37385392


Insomnia symptoms among older adults during the first year of the COVID-19 pandemic: A longitudinal study

Author(s): Gong K; Garneau J; Grenier S; Vasiliadis HM; Dang-Vu TT; Dialahy IZ; Gouin JP;

Objective: To identify sociodemographic, psychological, and health factors related to trajectories of insomnia symptoms in older adults during the COVID-19 pandemic. Methods: From May 2020 to May 2021, 644 older adults (mean age = 78.73, SD = 5.60) completed telephone-administered self-reported measures (ie, Insomnia Severity Index, consensus sleep diari ...

Article GUID: 37380593


Divergent directed evolution of a TetR-type repressor towards aromatic molecules

Author(s): Nasr MA; Martin VJJ; Kwan DH;

Reprogramming cellular behaviour is one of the hallmarks of synthetic biology. To this end, prokaryotic allosteric transcription factors (aTF) have been repurposed as versatile tools for processing small molecule signals into cellular responses. Expanding the toolbox of aTFs that recognize new inducer molecules is of considerable interest in many applicat ...

Article GUID: 37377432


Call to action: equity, diversity, and inclusion in emergency medicine resident physician selection

Author(s): Primavesi R; Patocka C; Burcheri A; Coutin A; Elhalwi AM; Ali A; Pandya A; Gagné A; Johnston B; Thoma B; LeBlanc C; Fovet F; Gallinger J; Mohadeb J; Ragheb M; Dong S; Smith S; Oyedokun T; Newmarch T; Knight V; McColl T;

Objectives: This call to action seeks to improve emergency care in Canada for equity-deserving communities, enabled by equitable representation among emergency physicians nationally. Specifically, this work describes current resident selection processes and makes recommendations to enhance the eq ...

Article GUID: 37368231


Macrogenetics reveals multifaceted influences of environmental variation on vertebrate population genetic diversity across the Americas

Author(s): Lawrence ER; Pedersen EJ; Fraser DJ;

The broad scale distribution of population-specific genetic diversity (GDP ) across taxa remains understudied relative to species diversity gradients, despite its relevance for systematic conservation planning. We used nuclear DNA data collected from 3678 vertebrate populations across the Americas to assess the role of environmental and spatial variables ...

Article GUID: 37365672


Intersection of Intimate Partner Violence, Partner Interference, and Family Supportive Supervision on Victims' Work Withdrawal

Author(s): Isola C; Granger S; Turner N; LeBlanc MM; Barling J;

This study investigates the link between intimate partner violence (IPV) and work withdrawal (including absence frequency, partial absenteeism, and turnover intentions) in the context of partners' interference with victims at work and family supportive supervision of victims at work. Using the work-home resources model, we propose that (1) partner int ...

Article GUID: 37359457


The Effects of Non-Pharmaceutical Interventions on COVID-19 Cases, Hospitalizations, and Mortality: A Systematic Literature Review and Meta-Analysis

Author(s): Peters JA; Farhadloo M;

Introduction: To assess the effects of various non-pharmaceutical interventions (NPI) on cases, hospitalizations, and mortality during the first wave of the COVID-19 pandemic. Methods: To empirically investigate the impacts of different NPIs on COVID-19-related health outcomes, a systematic literature review was conducted. We studied the effects of 10 NP ...

Article GUID: 37362389


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