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Minority Affirmations and the Boundaries of the Nation: Evidence From Québec

Author(s): Scott C; Bilodeau A; Gagnon A; Turgeon L;

Cultural criteria, like language skills and values, are salient features of nationalism discourse, reflecting imagined boundaries that separate ingroup from outgroup member when thinking about the nation. Despite their salience, the relationship between cultural membership criteria and other civic (attainable) or ethnic (ascriptive) national boundaries, a ...

Article GUID: 39925641


A database of magnetic resonance imaging-transcranial ultrasound co-registration

Author(s): Alizadeh M; Collins DL; Kersten-Oertel M; Xiao Y;

Purpose: As a portable and cost-effective imaging modality with better accessibility than Magnetic Resonance Imaging (MRI), transcranial sonography (TCS) has demonstrated its flexibility and potential utility in various clinical diagnostic applications, including Parkinson's disease and cerebrovascular conditions. To better understand the information ...

Article GUID: 39920905


Variations in caregiving patterns of spouses/partners and adult children of long-term care home residents in Ontario, Canada

Author(s): Ménard A; Podinic I; Conklin J; Hossain S; Arya A; Archibald D; Elliott J; Kothari A; Stolee P; Sveistrup H; Dehcheshmeh MM; Hsu AT;

Family involvement in care often continues after an individual moves into a long-term care (LTC) home. This cross-sectional study delves into the dynamics of family caregiving for LTC residents. Spouses/partners (n = 32, mean age 76) primarily focused on tasks such as mealtimes (53 %) and direct ...

Article GUID: 39919696


Imaging flow cytometry-based cellular screening elucidates pathophysiology in individuals with Variants of Uncertain Significance

Author(s): Muffels IJJ; Waterham HR; D' Alessandro G; Zagnoli-Vieira G; Sacher M; Lefeber DJ; Van der Vinne C; Roifman CM; Gassen KLI; Rehmann H; Van Haaften-Visser DY; Nieuwenhuis ESS; Jackson SP; Fuchs SA; Wijk F; van Hasselt P;

Background: Deciphering variants of uncertain significance (VUS) represents a major diagnostic challenge, partially due to the lack of easy-to-use and versatile cellular readouts that aid the interpretation of pathogenicity and pathophysiology. To address this challenge, we propose a high-through ...

Article GUID: 39920830


International interlaboratory study to normalize liquid chromatography-based mycotoxin retention times through implementation of a retention index system

Author(s): Kelman MJ; Renaud JB; McCarron P; Hoogstra S; Chow W; Wang J; Varga E; Patriarca A; Vaya AM; Visintin L; Nguyen T; De Boevre M; De Saeger S; Karanghat V; Vuckovic D; McMullin DR; Dall' Asta C; Ayeni K; Warth B; Huang M; Tittlemier S ...

Monitoring for mycotoxins in food or feed matrices is necessary to ensure the safety and security of global food systems. Due to a lack of standardized methods and individual laboratory priorities, most institutions have developed their own methods for mycotoxin determinations. Given the diversit ...

Article GUID: 39913989


Prioritizing Chemical Features in Non-targeted Analysis through Spatial Trend Analysis: Application to the Identification of Organic Chemicals Subject to Mountain Cold-Trapping

Author(s): Zhang X; Zhan F; Hao C; Lei YD; Wania F;

One of the challenges arising during non-targeted analysis (NTA) is that the number of detected chemical features is generally too large for detailed processing and interpretation. Here, we illustrate how the analysis of spatial trends in peak intensities can be an effective tool to prioritize chemical features in NTA. Specifically, features detected by g ...

Article GUID: 39912640


Adverse Childhood Experiences Influence Longitudinal Changes in Leptin But Not Adiponectin

Author(s): Matovic S; Rummel C; Neumann E; McGrath J; Gouin JP;

Objective: Adverse childhood experiences (ACEs) are associated with a greater risk of obesity and cardiometabolic disease. Adipokines, including leptin and adiponectin, play vital roles in biological processes linked to obesity and cardiometabolic risk. The adiponectin/leptin ratio may represent a marker of impaired hormonal regulation of adipose tissue. ...

Article GUID: 39909010


Association between aggression and ADHD polygenic scores and school-age aggression: the mediating role of preschool externalizing behaviors and adverse experiences

Author(s): Bouliane M; Boivin M; Kretschmer T; Lafreniere B; Paquin S; Tremblay R; Côté S; Gouin JP; Andlauer TFM; Petitclerc A; Ouellet-Morin I;

Individual differences in physical aggression (PA) are largely heritable. However, it remains unclear how genetic propensity for aggression manifests early in life and relates to school-age PA. Preschool externalizing behavior problems (EXT) and adverse experiences are known predictors of school- ...

Article GUID: 39907790


The PolyVent educational platform: An open mechanical ventilation platform for research and education

Author(s): Read RL; Bechard N; Suturin V; Zuiderwijk A; Mellenthin M;

The PolyVent is an open source mechanical ventilator meant for research and education. It prioritizes openness, modularity, repairability, and modifiability. An ESP32 microcontroller controls a proportional valve which precisely modulates pressure and flow from a mixing chamber into the airway. This chamber is fed with pressurized oxygen and medical air. ...

Article GUID: 39895909


Human recreational activity does not influence open cup avian nest survival in urban green spaces

Author(s): Cull CA; Guest MJ; Frei B; Ziter CD;

The breeding period of birds is a critical and sensitive portion of the annual cycle. Understanding how human use of urban green spaces affects nest survival can improve our understanding of conserving breeding bird populations in cities and support science-based management of urban green spaces that benefit both people and nature. We conducted a nest sur ...

Article GUID: 39897430


In-situ consolidation of thermoplastic composites by automated fiber placement: Characterization of defects

Author(s): Fereidouni M; Hoa SV;

The emergence of automated manufacturing of composites has not only transformed the manufacturing of optimized and geometrically complex structures but has also expanded the promising prospect of in-situ manufacturing of thermoplastic composites (TPC), where both material placement and consolidation are carried out by automated fiber placement (AFP) equip ...

Article GUID: 39895653


Use of lecanemab and donanemab in the Canadian healthcare system: Evidence, challenges, and areas for future research

Author(s): Smith EE; Phillips NA; Feldman HH; Borrie M; Ganesh A; Henri-Bhargava A; Desmarais P; Frank A; Badhwar A; Barlow L; Bartha R; Best S; Bethell J; Bhangu J; Black SE; Bocti C; Bronskill SE; Burhan AM; Calon F; Camicioli R; Campbell B; Coll ...

Lecanemab and donanemab are monoclonal antibody therapies that remove amyloid-beta from the brain. They are the first therapies that alter a fundamental mechanism, amyloid-beta deposition, in Alzheimer disease (AD). To inform Canadian decisions on approval and use of these drugs, the Canadian Con ...

Article GUID: 39893139


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