Author(s): Smith EE; Phillips NA; Feldman HH; Borrie M; Ganesh A; Henri-Bhargava A; Desmarais P; Frank A; Badhwar A; Barlow L; Bartha R; Best S; Bethell J; Bhangu J; Black SE; Bocti C; Bronskill SE; Burhan AM; Calon F; Camicioli R; Campbell B; Coll ...
Lecanemab and donanemab are monoclonal antibody therapies that remove amyloid-beta from the brain. They are the first therapies that alter a fundamental mechanism, amyloid-beta deposition, in Alzheimer disease (AD). To inform Canadian decisions on approval and use of these drugs, the Canadian Con ...
Article GUID: 39893139
Author(s): Lelonek-Kuleta B; Tovar ML; Bartczuk RP; Costes JM;
Aim: We examined the role of significant win experiences alongside psychosocial factors in the risk of problem gambling. Participants: The study involved adult pure-chance gamblers from representative Polish (n = 3143) and French samples (n = 5692). Measurements: The questionnaire encompassed socio-demographic details, gambling behaviours, significant w ...
Article GUID: 39889363
Author(s): Langmuir T; Wilson M; McCleary N; Patey AM; Mekki K; Ghazal H; Estey Noad E; Buchan J; Dubey V; Galley J; Gibson E; Fontaine G; Smith M; Alghamyan A; Thompson K; Crawshaw J; Grimshaw JM; Arnason T; Brehaut J; Michie S; Brouwers M; Presse ...
Background: Ensuring widespread COVID-19 vaccine uptake is a public health priority in Canada and globally, particularly within communities that exhibit lower uptake rates and are at a higher risk of infection. Public health units (PHUs) have leveraged many resources to promote the uptake of reco ...
Article GUID: 39891139
Author(s): Enea M; Beauregard J; De Bellis T; Faticov M; Laforest-Lapointe I;
The interactions between sugar maple (Acer saccharum, Marshall) and its microbial communities are important for tree fitness, growth, and establishment. Despite recent progress in our understanding of the rhizosphere and phyllosphere microbial communities of sugar maple, many outstanding knowledge gaps remain. This review delves into the relationships bet ...
Article GUID: 39881993
Author(s): Páez A; Gillman SO; Dogaheh SB; Carnes A; Dakterzada F; Barbé F; Dang-Vu TT; Ripoll GP;
Introduction: Changes in sleep physiology can predate cognitive symptoms by decades in persons with Alzheimer's disease (AD), but it remains unclear which sleep characteristics predict cognitive and neurodegenerative changes after AD onset. Methods: Using data from a prospective cohort of mild to moderate AD (n = 60), we analyzed non-rapid eye moveme ...
Article GUID: 39878233
Author(s): Ben-Porat T; Lahav Y; Cohen TR; Bacon SL; Buch A; Moizé V; Sherf-Dagan S;
Purpose of review: Protein intake is recognized as a key nutritional factor crucial for optimizing Metabolic Bariatric Surgery (MBS) outcomes by preventing protein malnutrition, preserving fat-free mass, and inducing satiety. This paper discusses the current evidence regarding protein intake and its impact on clinical outcomes following MBS. Recent findi ...
Article GUID: 39878797
Author(s): Young K; Browne K;
This article considers the multiple relations that emerge from and between Facebook commenters, as well as between commenters, researchers, and the research project during recruitment. To do so, we draw on our experiences of recruiting individuals who have concerns about or are opposed to a range of recent social and legal changes in 'post-equality ...
Article GUID: 39877298
Author(s): Savard MA; Coffey EBJ;
Misophonia is a disorder in which specific common sounds such as another person breathing or chewing, or the ticking of a clock, cause an atypical negative emotional response. Affected individuals may experience anger, irritability, annoyance, disgust, and anxiety, as well as physiological autonomic responses, and may find everyday environments and contex ...
Article GUID: 39874936
Author(s): Feola S; Al-Nabelsi L; Tam BT; Near J; Morais JA; Santosa S;
Objective: Compared to adulthood-onset obesity (AO), those with childhood-onset obesity (CO) are at greater risk of metabolic disease. However, the differences between these two obesity phenotypes are not clear. The aim of this study is to investigate how the age of obesity onset (CO vs. AO) affects the use of intramyocellular (IMCL) and extramyocellular ...
Article GUID: 39875595
Author(s): Bacon SL; Lavoie KL; Buckeridge D; Dietz WH; Freedland KE; Grimshaw JM; Jaworski BK; Laur C; Marques MM; Michie S; Powell LH; Rothman AJ; Whitmarsh L;
No abstract available
Article GUID: 39873378
Author(s): Zhang X; Bowman DT; Diamond ML; Helm P; Jobst KJ; Hao C; Kleywegt S; Zhang ZF; Marvin C; Zhang X;
Coal tar-related products as a source of polycyclic aromatic compounds (PACs) are particularly concerning due to high PAC concentrations and inadequate source management. Benzo[b]carbazole, a benzocarbazole isomer exclusively found in coal tar-derived products, acts as an ideal marker to distingu ...
Article GUID: 39870568
Author(s): Onana VE; Beisner BE; Walsh DA;
Human activities such as agriculture and urban development are linked to water quality degradation. Canada represents a large and heterogeneous landscape of freshwater lakes, where variations in climate, geography and geology interact with land cover alteration to influence water quality differently across regions. In this study, we investigated the influ ...
Article GUID: 39868666
