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Improved Parent-Child Interactions Predict Reduced Internalizing Symptoms Among the Offspring of Parents with Bipolar Disorder Undergoing a Prevention Program: A Proof-of-Concept Study

Author(s): Serravalle L; Iacono V; Wilson AL; Orlando MA; Tsekova V; Ellenbogen MA;

The offspring of parents with bipolar disorder (OBD) exhibit elevated rates of psychopathology. However, preventative interventions are lacking. Using a quasi-experimental design with an assessment-only control group, we examined if a 12-week program (entitled Reducing Unwanted Stress in the Home, RUSH) decreases internalizing and externalizing symptoms i ...

Article GUID: 33544277


Multilevel Contextual Analysis of Poker Cash Game Gambling

Author(s): Dussault F; Brunelle N; Dufour M; Kairouz S;

This article examines the effect of gambling location on the frequency, expenditure, and time spent on cash game poker in relation to individual characteristics of gamblers. Data were drawn from a 2012 Québec epidemiological gambling survey. The quantitative analysis used multilevel methods to model the dual-level hierarchical design of gambling location ...

Article GUID: 33538954


Assessing optimal colour and illumination to facilitate reading.

Author(s): Morrice E, Murphy C, Soldano V, Addona C, Wittich W, Johnson AP

PURPOSE: This study examined the effectiveness of the LuxIQ, the Apple iPad and a smart bulb in assessing optimal colour and illumination to facilitate reading in younger, older and visually impaired adults. METHODS: Participants read standardised texts at baseline (normal lighting/no device), then using the Apple iPad, LuxIQ and smart bulb, with their no ...

Article GUID: 33533095


Childhood poverty and psychological well-being: The mediating role of cumulative risk exposure.

Author(s): Evans GW, De France K

The current study assessed whether the proportion of childhood (age 0-9 years) in poverty altered the developmental trajectories (ages 9-24) of multimethodological indicators of psychological well-being. In addition, we tested whether exposure to cumulative risk over time mediated the association between poverty exposure and psychological well-being. Meas ...

Article GUID: 33526153


CCCDTD5: Clinical role of neuroimaging and liquid biomarkers in patients with cognitive impairment

Author(s): Brisson M; Brodeur C; Létourneau-Guillon L; Masellis M; Stoessl J; Tamm A; Zukotynski K; Ismail Z; Gauthier S; Rosa-Neto P; Soucy JP;

Since 1989, four Canadian Consensus Conferences on the Diagnosis and Treatment of Dementia (CCCDTDs) have provided evidence-based dementia diagnostic and treatment guidelines for Canadian clinicians and researchers. We present the results from the Neuroimaging and Fluid Biomarkers Group of the 5t ...

Article GUID: 33532543


AHNAK C-Terminal Peptide Membrane Binding-Interactions between the Residues 5654-5673 of AHNAK and Phospholipid Monolayers and Bilayers.

Author(s): Yan X, Noël F, Marcotte I, DeWolf CE, Warschawski DE, Boisselier E

The dysferlin membrane repair complex contains a small complex, S100A10-annexin A2, which initiates membrane repair by recruiting the protein AHNAK to the membrane, where it interacts via binding sites in the C-terminal region. However, no molecular data are available for the membrane binding of the various proteins involved in this complex. Therefore, th ...

Article GUID: 31825630


Gender is Key: Girls' and Boys' Cortisol Differs as a Factor of Socioeconomic Status and Social Experiences During Early Adolescence.

Author(s): Wright L, Bukowski WM

The risks associated with negative peer relationships and low socioeconomic status (SES), and how they impact diurnal cortisol and the cortisol response to negative experiences, have never been studied together in early adolescents; this study aims to fill this gap in the literature. Saliva was collected from 95 early adolescents (Mage?=?10.80, SD?=?0.72) ...

Article GUID: 33515375


Validation of a Portable Game Controller to Assess Peak Expiratory Flow Against Conventional Spirometry in Children: Cross-sectional Study.

Author(s): Chelabi K, Balli F, Bransi M, Gervais Y, Marthe C, Tse SM

BACKGROUND: International asthma guidelines recommend the monitoring of peak expiratory flow (PEF) as part of asthma self-management in children and adolescents who poorly perceive airflow obstruction, those with a history of severe exacerbations, or those who have difficulty controlling asthma. Measured with a peak flow meter, PEF represents a person' ...

Article GUID: 33512326


Recent Advances of DNA Tetrahedra for Therapeutic Delivery and Biosensing.

Author(s): Copp W, Pontarelli A, Wilds CJ

The chemical and self-assembly properties of nucleic acids make them ideal for the construction of discrete structures and stimuli-responsive devices for a diverse array of applications. Amongst the various three-dimensional assemblies, DNA tetrahedra are of particular interest as these structures have been shown to be readily taken up by the cell without ...

Article GUID: 33506614


Towards Detecting Biceps Muscle Fatigue in Gym Activity Using Wearables.

Author(s): Elshafei M, Shihab E

Fatigue is a naturally occurring phenomenon during human activities, but it poses a bigger risk for injuries during physically demanding activities, such as gym activities and athletics. Several studies show that bicep muscle fatigue can lead to various injuries that may require up to 22 weeks of treatment. In this work, we adopt a wearable approach to de ...

Article GUID: 33498702


Molecular mechanisms of neurodegeneration in the entorhinal cortex that underlie its selective vulnerability during the pathogenesis of Alzheimer's disease.

Author(s): Olajide OJ, Suvanto ME, Chapman CA

The entorhinal cortex (EC) is a vital component of the medial temporal lobe, and its contributions to cognitive processes and memory formation are supported through its extensive interconnections with the hippocampal formation. During the pathogenesis of Alzheimer's disease (AD), many of the earliest degenerative changes are seen within the EC. Neurod ...

Article GUID: 33495355


Why did the kitten cross the road? A meditation on positive versus negative reinforcement in addiction.

Author(s): Leyton M

J Psychiatry Neurosci. 2021 Jan 21; 46(1):E184-E185 Authors: Leyton M PMID: 33497168 [PubMed - as supplied by publisher]

Article GUID: 33497168


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