Author(s): McCallum G, Potvin-Trottier L

Mathematical models play an important role in the design of synthetic gene circuits, by guiding the choice of biological components and their assembly into novel gene networks. Here, we present a guide for biologists to build and utilize models of gene networks (synthetic or natural) to analyze dynamical properties of these networks while considering the ...

Article GUID: 33405217

Author(s): Julien CA, Lavoie KL, Ribeiro PAB, Dragomir AI, Mercier LA, Garneau PY, Pescarus R, Bacon SL

Metabolic and bariatric surgery (MBS) yields unprecedented clinical outcomes, though variability is high in weight change and health benefits. Behavioral weight management (BWM) interventions may optimize MBS outcomes. However, there is a lack of an evidence base to inform their use in practice, ...

Article GUID: 33403754

Author(s): Tian X, An C, Chen Z, Tian Z

The global outbreak and spread of COVID-19 had a significant impact on the environment of urban areas. This study aimed to provide a new insight into the urban transportation and air pollutant emission of representative Canadian cities impacted by this pandemic. The consumption of urban transportation fuel was analyzed and the corresponding CO2 emissions ...

Article GUID: 33401062

Author(s): Azar N, Booij L, Muckle G, Arbuckle TE, Séguin JR, Asztalos E, Fraser WD, Lanphear BP, Bouchard MF

BACKGROUND: Prenatal exposure to polybrominated diphenyl ethers (PBDEs) has been associated with adverse neurodevelopmental outcomes in children, but evidence remains mixed regarding sex differences in this association. OBJECTIVE: To examine the prospective association between prenatal PBDE expos ...

Article GUID: 33395941

Author(s): DuBois JM, Mathotaarachchi S, Rousset OG, Sziklas V, Sepulcre J, Guiot MC, Hall JA, Massarweh G, Soucy JP, Rosa-Neto P, Kobayashi E

To determine the extent of metabotropic glutamate receptor type 5 (mGluR5) network abnormalities associated with focal cortical dysplasia (FCD), we performed graph theoretical analysis of [11C]ABP688 PET binding potentials (BPND), which allows for quantification of mGluR5 availability. Undirected ...

Article GUID: 33401137

Author(s): Demers K, Morin C, Collette L, DeMont R

Background: The World Health Organization benchmarks for osteopathic training consider cranial osteopathy as an important manual skill. Studies of cranial manual therapy have exhibited poor reliability. The aim of this study was to investigate the inter-rater reliability of the manual mobility tests of the spheno-occipital synchondrosis (SOS), and the tem ...

Article GUID: 33395535

Author(s): Poulin-Dubois D, Dutemple E, Burnside K

Theory of mind is defined as the understanding that mental states predict and explain people's behaviors. It develops around the age of 4 but seems to remain deficient in people with ASD, whereas other forms of naïve understanding remain intact. This study compares children with ASD to neurotypical children on tasks measuring naïve psychology, physics ...

Article GUID: 33385282

Author(s): Gillet N, Morin AJS, Mokounkolo R, Réveillère C, Fouquereau E

BACKGROUND AND OBJECTIVES: This research identified profiles characterized by distinct levels of overcommitment, rumination, psychological detachment (Studies 1 and 2), and need for recovery (Study 2). This research also considers the role of hindrance demands and resources in the prediction of profile membership, and the outcomes of these profiles. METHO ...

Article GUID: 33380222

Author(s): Vongas JG; Al Hajj R; Fiset J;

Personal distress is a building block of empathy, yet has received scant attention in studies of individual differences in leadership. We investigate whether the effect of leader emergence on men's distress is influenced by their personalized power motive (p Power) and changes in their testosterone (T) and cortisol (C) levels. In an experiment involvi ...

Article GUID: 33378391

Author(s): Alankar B; Sharma G; Kaur H; Valverde R; Chang V;

Cloud computing has emerged as the primary choice for developers in developing applications that require high-performance computing. Virtualization technology has helped in the distribution of resources to multiple users. Increased use of cloud infrastructure has led to the challenge of developing a load balancing mechanism to provide optimized use of res ...

Article GUID: 33371361

Author(s): Yao S, Feng Y, Islam A, Shrivastava M, Gu H, Lu Y, Sheng J, Whiteway M, Feng J

The polymorphous cellular shape of Candida albicans, in particular the transition from a yeast to a filamentous form, is crucial for either commensalism or life-threatening infections of the host. Various external or internal stimuli, including serum and nutrition starvation, have been shown to regulate filamentous growth primarily through two classical s ...

Article GUID: 33363697

Author(s): Sohrabi Kashani A, Piekny A, Packirisamy M

Determining the characteristics and localization of nanoparticles inside cells is crucial for nanomedicine design for cancer therapy. Hyperspectral imaging is a fast, straightforward, reliable, and accurate method to study the interactions of nanoparticles and intracellular components. With a hyperspectral image, we could collect spectral information cons ...

Article GUID: 33365137