Author(s): Sohrabi Kashani A, Piekny A, Packirisamy M

Determining the characteristics and localization of nanoparticles inside cells is crucial for nanomedicine design for cancer therapy. Hyperspectral imaging is a fast, straightforward, reliable, and accurate method to study the interactions of nanoparticles and intracellular components. With a hyperspectral image, we could collect spectral information cons ...

Article GUID: 33365137

Author(s): Belleville S, Mellah S, Cloutier S, Dang-Vu TT, Duchesne S, Maltezos S, Phillips N, Hudon C, CIMA-Q group

INTRODUCTION: Cognitive reserve can be defined as a property of the brain that enables an individual to sustain cognitive performance in spite of age-related neural changes. This study uses brain imaging to identify which cognitive reserve mechanisms protect against the detrimental effect of hipp ...

Article GUID: 33360019

Author(s): Wölk C, Youssef H, Guttenberg T, Marbach H, Vizcay-Barrena G, Shen C, Brezesinski G, Harvey RD

Ion pairing between the major phospholipids of the Staphylococcus aureus plasma membrane (phosphatidylglycerol - PG and lysyl-phosphatidylglycerol - LPG) confers resistance to antimicrobial peptides and other antibiotics. We developed 3adLPG, a stable synthetic analogue which can substitute for t ...

Article GUID: 32065707

Author(s): Orabi EA; English AM;

Long associated with cell death, hydrogen peroxide (H2O2) is now known to perform many physiological roles. Unraveling its biological mechanisms of action requires atomic-level knowledge of its association with proteins and lipids, which we address here. High-level [MP2(full)/6-311++G(3df,3pd)] ab initio calculations reveal skew rotamers as the lowest-ene ...

Article GUID: 33356279

Author(s): Parent M; Albuquerque I; Tiwari A; Cassani R; Gagnon JF; Lafond D; Tremblay S; Falk TH;

With the burgeoning of wearable devices and passive body/brain-computer interfaces (B/BCIs), automated stress monitoring in everyday settings has gained significant attention recently, with applications ranging from serious games to clinical monitoring. With mobile users, however, challenges arise due to other overlapping (and potentially confounding) phy ...

Article GUID: 33363449

Author(s): Yitshak-Sade M, Nethery R, Schwartz JD, Mealli F, Dominici F, Di Q, Abu Awad Y, Ifergane G, Zanobetti A

BACKGROUND: Although long-term exposure to particulate matter METHODS: We constructed daily zipcode counts of hospital admissions of Medicare beneficiaries older than 65 across the United-States (2000-2014). We obtained daily PM2.5 estimates from a satellite-based model. A propensity score matchi ...

Article GUID: 33065503

Author(s): Alballa M, Butler G

BACKGROUND: Membrane proteins are key gates that control various vital cellular functions. Membrane proteins are often detected using transmembrane topology prediction tools. While transmembrane topology prediction tools can detect integral membrane proteins, they do not address surface-bound proteins. In this study, we focused on finding the best techniq ...

Article GUID: 33349234

Author(s): Al-Turjman F, Hamouda W, Mumtaz S

Big Data. 2020 Dec; 8(6):542-543 Authors: Al-Turjman F, Hamouda W, Mumtaz S PMID: 33347369 [PubMed - as supplied by publisher]

Article GUID: 33347369

Author(s): Salmanian S; Pezeshk H; Sadeghi M;

Background: Predicting physical interaction between proteins is one of the greatest challenges in computational biology. There are considerable various protein interactions and a huge number of protein sequences and synthetic peptides with unknown interacting counterparts. Most of co-evolutionary methods discover a combination of physical interplays and f ...

Article GUID: 33334319

Author(s): Albuquerque I; Tiwari A; Parent M; Cassani R; Gagnon JF; Lafond D; Tremblay S; Falk TH;

Assessment of mental workload is crucial for applications that require sustained attention and where conditions such as mental fatigue and drowsiness must be avoided. Previous work that attempted to devise objective methods to model mental workload were mainly based on neurological or physiological data collected when the participants performed tasks that ...

Article GUID: 33335465

Author(s): Blais AR, Gillet N, Houle SA, Comeau CA, Morin AJS

The present study examined the distinct configurations, or profiles, taken by work fatigue dimensions among samples of military (n = 1,436) and civilian (n = 2,477) employees. We also tested profile similarity across these two samples of employees. In addition, this research documented the relations between the identified work fatigue profiles, one predic ...

Article GUID: 33329261

Author(s): Marentette P, Furman R, Suvanto ME, Nicoladis E

Pantomime has long been considered distinct from co-speech gesture. It has therefore been argued that pantomime cannot be part of gesture-speech integration. We examine pantomime as distinct from silent gesture, focusing on non-co-speech gestures that occur in the midst of children's spoken narratives. We propose that gestures with features of pantomi ...

Article GUID: 33329222