Author(s): Bondon N; Mandl GA; Mena-Giraldo P; Ferron Z; Sadeghipour N; DeWolf C; Capobianco JA;
We report the synthesis of supported lipid bilayer (SLB)-coated radioluminescent nanoparticles (RLNPs) possessing a lanthanide-based core for low-dose X-ray activated photodynamic therapy (XPDT). Methylene blue (MB) photosensitizer molecules, incorporated within the SLB, are excited by energy transfer from europium, leading to an enhanced generation of re ...
Article GUID: 41059546
Author(s): Malka G; Salucci V; Bergdahl A;
Angiogenesis, the formation of new blood vessels, is crucial in ischemic heart disease to improve blood supply to the heart. Meanwhile, in cancer, inhibiting angiogenesis can limit tumor growth by reducing oxygen and nutrients. Calcium ions, key in cellular functions like proliferation and migration, play an important role in this process. TRPV4, a calciu ...
Article GUID: 41056565
Author(s): Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Yeo BTT;
Sleep is essential for optimal functioning and health. Interconnected to multiple biological, psychological, and socio-environmental factors (i.e., biopsychosocial factors), the multidimensional nature of sleep is rarely capitalized on in research. Here, we deployed a data-driven approach to iden ...
Article GUID: 41056215
Author(s): Pierre Bikorimana J; Caveney NA; El-Hachem N; Mandl GA; Capobianco JA; Stanga D; Abusarah J; Hancock MA; Farah R; Gonçalves MP; Falzarano D; Liao M; Hamonic G; Liu Q; Beaudoin S; Talbot S; Rafei M;
Despite the recent control of COVID-19, the devastating effects caused by the 3-year pandemic highlight the importance of developing effective vaccines to rapidly address future outbreaks. The present study describes a novel Spike (Sp) protein-based vaccine formulation using the Accum platform. A ...
Article GUID: 41054531
Author(s): Pan S; Wang X; Guo T; An H; Guo Y; Chen Z; Lian J; Guo J;
Inefficient electron transfer is one of the main challenges in practical denitrification applications. To address this issue, a novel ternary mediator functional material (Mxene@Fe-TA) was successfully synthesized, which exhibited pseudocapacitive properties to facilitate electron mediation and distribution. Batch experiments revealed that 50 mg/L MXene@F ...
Article GUID: 41043789
Author(s): Fang X; Holding AC; Audet ÉC; Thai H; Koestner R;
Previous research has revealed lower vaccination rates among Black communities relative to other racial-ethnic communities in North America. However, there remains a gap in understanding the motivational barriers contributing to these persistent disparities. Grounded in Self-Determination Theory, the current research aimed to examine the effects of differ ...
Article GUID: 41043306
Author(s): Kalenkovich E; Koorathota S; Tor S; Amatuni A; Egan-Dailey S; Moore C; Laing C; Garrison H; Baudet G; Bulgarelli F; Uner S; Righter L; Bergelson E;
This paper describes a dataset consisting of manually annotated nouns from a corpus of longitudinal day-long audio and hour-long video recordings collected monthly from 44 babies from age 6 months to age 17 months. This dataset was created as part of a larger project, called SEEDLingS, that exami ...
Article GUID: 41034519
Author(s): Liu L; Gillet AP; Akiki C; Tian L; Ma Y; Zhang X; Bowman DT; Wania F; Delbès G; Apparicio P; Bayen S;
Air pollution is closely associated with increased lung cancer incidence and mortality. Because many semi-volatile industrial chemicals, pesticides and combustion by-products are endocrine-disrupting or genotoxic, their mixtures in outdoor urban air, even at trace levels, could have cumulative ef ...
Article GUID: 41033295
Author(s): Li KZH; Campos J; Pichora-Fuller MK;
Following from the World Health Organization's consideration of multiple systems (e.g., sensory, motor, and cognitive) in defining healthy aging, this study presents a review of research on training that has the primary goal of improving complex multitasking outcomes that approximate the everyday contexts in which hearing is important, whether or not ...
Article GUID: 41036263
Author(s): Patel MA; Boribong BP; Sinha H; Xiao B; Xie K; Vo PQN; Chin AB; Ellouzi A; Little SR; Shih SCC; Wu H; Muller WJ; Hirukawa A;
Article GUID: 41028230
Author(s): Nutter S; Waugh R; McEachran E; Toor A; Shelley J; Alberga AS; Forhan M; Kirk SF; Nagpal TS; Patton I; Ramos Salas X; Russell-Mayhew S;
Weight stigma negatively impacts people with higher weights across the lifespan as well as social contexts and can lead to weight discrimination. As weight is not a protected identity in Canadian human rights legislation, it is important to better understand how weight discrimination is being arg ...
Article GUID: 41029703
Author(s): Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Fajardo Valdez A; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Stri ...
The PResymptomatic EValuation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) is an investigator-driven study that was created in 2011 and enrolled cognitively normal older adults with a family history of sporadic AD. Participants are deeply phenotyped and have now be ...
Article GUID: 41020412
