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Improvements in cardiorespiratory fitness, muscle strength and body composition to modest weight loss are similar in those with adult- versus childhood-onset obesity

Author(s): Lucas Guimarães Almeida

Adults who have had obesity from childhood are at greater risk of obesity-related comorbidities compared to those who only develop obesity in adulthood. The main way of mitigating these risks in obesity is with weight loss, which has been shown to positively affect the cardiorespiratory fitness (CRF) and body composition of adults. However, it is unclear ...

Article GUID: 37794721


The Adr1 transcription factor directs regulation of the ergosterol pathway and azole resistance in Candida albicans

Author(s): Shrivastava M; Kouyoumdjian GS; Kirbizakis E; Ruiz D; Henry M; Vincent AT; Sellam A; Whiteway M;

Transcription factors (TFs) play key roles in cellular regulation and are critical in the control of drug resistance in the fungal pathogen Candida albicans. We found that activation of the transcription factor C4_02500C_A (Adr1) conferred significant resistance against fluconazole. In Saccharomy ...

Article GUID: 37791798


Comparison of Radiologists and Deep Learning for US Grading of Hepatic Steatosis

Author(s): Vianna P; Calce SI; Boustros P; Larocque-Rigney C; Patry-Beaudoin L; Luo YH; Aslan E; Marinos J; Alamri TM; Vu KN; Murphy-Lavallée J; Billiard JS; Montagnon E; Li H; Kadoury S; Nguyen BN; Gauthier S; Therien B; Rish I; Belilovsky E; Wolf ...

Background Screening for nonalcoholic fatty liver disease (NAFLD) is suboptimal due to the subjective interpretation of US images. Purpose To evaluate the agreement and diagnostic performance of radiologists and a deep learning model in grading hepatic steatosis in NAFLD at US, with biopsy as the ...

Article GUID: 37787678


Hydroxyl radical production by abiotic oxidation of pyrite under estuarine conditions: The effects of aging, seawater anions and illumination

Author(s): Liu R; Dai Y; Feng Y; Sun S; Zhang X; An C; Zhao S;

Pyrite is widely distributed in estuarine sediments as an inexpensive natural Fenton-like reagent, however, the mechanism on the hydroxyl radical (HO·) production by pyrite under estuarine environmental conditions is still poorly understood. The batch experiments were performed to investigate the effects of estuarine conditions including aging (in air, in ...

Article GUID: 37778841


Interplay between male quality and male-female compatibility across episodes of sexual selection

Author(s): Mahdjoub H; Khelifa R; Roy J; Sbilordo SH; Zeender V; Perdigón Ferreira J; Gourgoulianni N; Lüpold S;

The processes underlying mate choice profoundly influence the dynamics of sexual selection and the evolution of male sexual traits. Consistent preference for certain phenotypes may erode genetic variation in populations through directional selection, whereas divergent preferences (e.g., genetical ...

Article GUID: 37774022


Advances in the design and use of carbon dots for analytical and biomedical applications

Author(s): Adeola AO; Clermont-Paquette A; Piekny A; Naccache R;

Carbon dots (CDs) have garnered significant interest for their potential use in multiple applications due to their size, fluorescent properties, high photostability, low toxicity and biocompatibility. CDs can be tailored for specific needs, as they can be synthesized with diverse precursors and techniques for functionalization. Since the applications of C ...

Article GUID: 37757783


Cavitation-Enhanced Drug Delivery and Immunotherapy

Author(s): Helfield B; Sirsi S; Kwan J; Gray M;

Welcome to this special issue on Cavitation-Enhanced Drug Delivery and Immunotherapy-a rapidly evolving area that has been buoyed in recent years by the development of methods harnessing the activity of ultrasound-stimulated bubbles known as cavitation [...].

Article GUID: 37765176


The Effects of Combined Motor Control and Isolated Extensor Strengthening versus General Exercise on Paraspinal Muscle Morphology, Composition, and Function in Patients with Chronic Low Back Pain: A Randomized Controlled Trial

Author(s): Fortin M; Rye M; Roussac A; Montpetit C; Burdick J; Naghdi N; Rosenstein B; Bertrand C; Macedo LG; Elliott JM; Dover G; DeMont R; Weber MH; Pepin V;

Low back pain (LBP), a globally widespread and persistent musculoskeletal disorder, benefits from exercise therapy. However, it remains unclear which type leads to greater changes in paraspinal muscle health. This study aimed to (1) compare the effects of a combined motor control and isolated lum ...

Article GUID: 37762861


Data-Weighted Multivariate Generalized Gaussian Mixture Model: Application to Point Cloud Robust Registration

Author(s): Ge B; Najar F; Bouguila N;

In this paper, a weighted multivariate generalized Gaussian mixture model combined with stochastic optimization is proposed for point cloud registration. The mixture model parameters of the target scene and the scene to be registered are updated iteratively by the fixed point method under the framework of the EM algorithm, and the number of components is ...

Article GUID: 37754943


A Comparative Study of the Self-Cleaning and Filtration Performance of Suspension Plasma-Sprayed TiO2 Ultrafiltration and Microfiltration Membranes

Author(s): Alebrahim E; Moreau C;

This study investigated the performance of photocatalytic titanium dioxide microfiltration membranes with an average pore size of approximately 180 nm and ultrafiltration membranes with an average pore size of around 40 nm fabricated with the suspension plasma spray process. The membranes were evaluated for their filtration performance using SiO2 particle ...

Article GUID: 37755172


Microhabitat conditions drive uncertainty of risk and shape neophobic responses in Trinidadian guppies, Poecilia reticulata

Author(s): Feyten LEA; Ramnarine IW; Brown GE;

In response to uncertain risks, prey may rely on neophobic phenotypes to reduce the costs associated with the lack of information regarding local conditions. Neophobia has been shown to be driven by information reliability, ambient risk and predator diversity, all of which shape uncertainty of risk. We similarly expect environmental conditions to shape un ...

Article GUID: 37753307


Author Correction: Native diversity buffers against severity of non-native tree invasions

Author(s): Delavaux CS; Crowther TW; Zohner CM; Robmann NM; Lauber T; van den Hoogen J; Kuebbing S; Liang J; de-Miguel S; Nabuurs GJ; Reich PB; Abegg M; Adou Yao YC; Alberti G; Almeyda Zambrano AM; Alvarado BV; Alvarez-Dávila E; Alvarez-Loayza P; Alves LF; Ammer C; Antón-Fernández C; Araujo-Murakami A; Arro ...

No abstract

Article GUID: 37752352


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