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Iron Deposition and Distribution Across the Hippocampus Is Associated with Pattern Separation and Pattern Completion in Older Adults at Risk for Alzheimer's Disease

Author(s): Zhou J; Wearn A; Huck J; Hughes C; Baracchini G; Tremblay-Mercier J; Poirier J; Villeneuve S; Tardif CL; Chakravarty MM; Daugherty AM; Gauthier CJ; Turner GR; Spreng RN;

Elevated iron deposition in the brain has been observed in older adult humans and persons with Alzheimer's disease (AD), and has been associated with lower cognitive performance. We investigated the impact of iron deposition, and its topographical distribution across hippocampal subfields and ...

Article GUID: 38388425


Fear of depression recurrence among individuals with remitted depression: a qualitative interview study

Author(s): Stephanie T Gumuchian

CONCLUSIONS: The concept of FoDR may present a window into understanding the unique cognitive and behavioural changes that occur following MDD remission and underlie depression recurrence. Future research should aim to identify underlying individual differences and characteristics of the disorder that may influence the presence and impact of FoDR. Finally ...

Article GUID: 38383311


Ending the overdose epidemic by ending the war on drug users: Can this work?

Author(s): Leyton M; Krausz RM;

No abstract available

Article GUID: 38383036


Hydrothermal synthesis and electrochemical properties of Sn-based peanut shell biochar electrode materials

Author(s): Wang Y; Wang H; Ji J; You T; Lu C; Liu C; Song Y; Chen Z; Zhu S;

Using activated-carbon-based electrodes derived from waste biomass in super-capacitor energy technologies is an essential future strategy to achieve sustainable energy and environmental protection. Biomass feed-stocks such as bamboo and straw have been used to prepare activated carbon-based electrodes. This experiment used peanut shells (waste biomass) as ...

Article GUID: 38380232


Cone allometry and seed protection from fire are similar in serotinous and nonserotinous conifers

Author(s): Greene DF; Kane JM; Pounden E; Michaletz ST;

Serotiny is an adaptive trait that allows certain woody plants to persist in stand-replacing fire regimes. However, the mechanisms by which serotinous cones avoid seed necrosis and nonserotinous species persist in landscapes with short fire cycles and serotinous competitors remain poorly understood. To investigate whether ovulate cone traits that enhance ...

Article GUID: 38375897


Transductive meta-learning with enhanced feature ensemble for few-shot semantic segmentation

Author(s): Karimi A; Poullis C;

This paper addresses few-shot semantic segmentation and proposes a novel transductive end-to-end method that overcomes three key problems affecting performance. First, we present a novel ensemble of visual features learned from pretrained classification and semantic segmentation networks with the same architecture. Our approach leverages the varying discr ...

Article GUID: 38369571


SCANED: Siamese collateral assessment network for evaluation of collaterals from ischemic damage

Author(s): Aktar M; Xiao Y; Tehrani AKZ; Tampieri D; Rivaz H; Kersten-Oertel M;

This study conducts collateral evaluation from ischemic damage using a deep learning-based Siamese network, addressing the challenges associated with a small and imbalanced dataset. The collateral network provides an alternative oxygen and nutrient supply pathway in ischemic stroke cases, influencing treatment decisions. Research in this area focuses on a ...

Article GUID: 38364600


The effect of Wharton's jelly-derived stem cells seeded/boron-loaded acellular scaffolds on the healing of full-thickness burn wounds in the rat model

Author(s): Nikzad S; Same S; Safiri S; Dolati S; Roushangar Zineh B; Meshgi S; Roshangar L; Sahin F;

Burn wounds are the most destructive and complicated type of skin or underlying soft tissue injury that are exacerbated by a prolonged inflammatory response. Several cell-based therapeutic systems through the culturing of potent stem cells on modified scaffolds have been developed to direct the burn healing challenges. In this context, a new regenerative ...

Article GUID: 38364284


Variation the in relationship between urban tree canopy and air temperature reduction under a range of daily weather conditions

Author(s): Locke DH; Baker M; Alonzo M; Yang Y; Ziter CD; Murphy-Dunning C; O' Neil-Dunne JPM;

Mitigating heat is a vital ecosystem service of trees, particularly with climate change. Land surface temperature measures captured at a single time of day (in the morning) dominate the urban heat island literature. Less is known about how local tree canopy and impervious surface regulate air temperature throughout the day, and/or across many days with va ...

Article GUID: 38352758


Correction: Factors associated with change in moderate or severe symptoms of anxiety and depression in community-living adults and older adults during the COVID-19 pandemic

Author(s): Helen-Maria Vasiliadis

No abstract available

Article GUID: 38347372


Establishing a framework for best practices for quality assurance and quality control in untargeted metabolomics

Author(s): Mosley JD; Schock TB; Beecher CW; Dunn WB; Kuligowski J; Lewis MR; Theodoridis G; Ulmer Holland CZ; Vuckovic D; Wilson ID; Zanetti KA;

Background: Quality assurance (QA) and quality control (QC) practices are key tenets that facilitate study and data quality across all applications of untargeted metabolomics. These important practices will strengthen this field and accelerate its success. The Best Practices Working Group (WG) wi ...

Article GUID: 38345679


Association of childhood externalizing, internalizing, comorbid problems with criminal convictions by early adulthood

Author(s): Melissa Commisso

Childhood externalizing problems have been linked with adult criminality. However, little is known about criminal outcomes among children with comorbid externalizing and internalizing problems. We examined the associations between profiles of behavioral problems during childhood (i.e., externalizing, internalizing, and comorbid) and criminality by early a ...

Article GUID: 38342065


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