Keyword search (4,163 papers available)

"Boivin M" Authored Publications:

Title Authors PubMed ID
1 Correction: Polygenic scores of obesity in childhood based on summary statistics from adults versus children Goulet D; Boivin M; Gravel C; Little J; Ouellet-Morin I; Gouin J; Dubois L; 41182116
CONCORDIA
2 Trajectories of childhood eating behaviors and their association with internalizing and externalizing symptoms in adolescence Dufour R; Breton É; Côté SM; Dubois L; Vitaro F; Boivin M; Tremblay RE; Booij L; 40883733
PSYCHOLOGY
3 Polygenic scores of obesity in childhood based on summary statistics from adults vs. children Goulet D; Boivin M; Gravel C; Little J; Ouellet-Morin I; Gouin JP; Dubois L; 40132211
CONCORDIA
4 Association between aggression and ADHD polygenic scores and school-age aggression: the mediating role of preschool externalizing behaviors and adverse experiences Bouliane M; Boivin M; Kretschmer T; Lafreniere B; Paquin S; Tremblay R; Côté S; Gouin JP; Andlauer TFM; Petitclerc A; Ouellet-Morin I; 39907790
PSYCHOLOGY
5 A multimodal neuroimaging study of youth at risk for substance use disorders: Functional magnetic resonance imaging and [18F]fallypride positron emission tomography Nikolic M; Cox SML; Jaworska N; Castellanos-Ryan N; Dagher A; Vitaro F; Brendgen M; Parent S; Boivin M; Côté S; Tremblay RE; Séguin JR; Leyton M; 39725679
CSBN
6 Prediction of depressive symptoms in young adults by polygenic score and childhood maltreatment: Results from a population-based birth cohort Scardera S; Geoffroy MC; Langevin R; Perret LC; Collin-Vézina D; Voronin I; Gouin JP; Meng X; Boivin M; Ouellet-Morin I; 39465601
PSYCHOLOGY
7 Childhood hyperactivity, eating behaviours, and executive functions: Their association with the development of eating-disorder symptoms in adolescence Dufour R; Breton É; Morin AJS; Côté SM; Dubois L; Vitaro F; Boivin M; Tremblay RE; Booij L; 37833803
PSYCHOLOGY
8 Childhood Overeating and Disordered Eating From Early Adolescence to Young Adulthood: A Longitudinal Study on the Mediating Role of BMI, Victimization and Desire for Thinness Breton É; Côté SM; Dubois L; Vitaro F; Boivin M; Tremblay RE; Booij L; 37270466
PSYCHOLOGY
9 Adolescent anxiety and pain problems: A joint, genome-wide investigation and pathway-based analysis Mascheretti S; Forni D; Lampis V; Fumagalli L; Paquin S; Andlauer TFM; Wang W; Dionne G; Brendgen MR; Vitaro F; Ouellet-Morin I; Rouleau G; Gouin JP; Côté S; Tremblay RE; Turecki G; Garon-Carrier G; Boivin M; Battaglia M; 37146008
PSYCHOLOGY
10 Depression, anxiety, and suicidal ideation in a population-based cohort of young adults before and during the first 12 months of the COVID-19 pandemic in Canada Gouin JP; MacNeil S; de la Torre-Luque A; Chartrand E; Chadi N; Rouquette A; Boivin M; Côté S; Geoffroy MC; 37093498
PSYCHOLOGY
11 Pathways of association between disordered eating in adolescence and mental health outcomes in young adulthood during the COVID-19 pandemic Loose T; Geoffroy MC; Orri M; Chadi N; Scardera S; Booij L; Breton E; Tremblay R; Boivin M; Coté S; 36482144
PSYCHOLOGY
12 Developmental trajectories of eating disorder symptoms: A longitudinal study from early adolescence to young adulthood Breton É; Dufour R; Côté SM; Dubois L; Vitaro F; Boivin M; Tremblay RE; Booij L; 35725645
PSYCHOLOGY
13 Depression and anxiety symptoms in young adults before and during the COVID-19 pandemic: evidence from a Canadian population-based cohort Watkins-Martin K; Orri M; Pennestri MH; Castellanos-Ryan N; Larose S; Gouin JP; Ouellet-Morin I; Chadi N; Philippe F; Boivin M; Tremblay RE; Côté S; Geoffroy MC; 34496901
PSYCHOLOGY
14 Polygenic scores differentially predict developmental trajectories of subtypes of social withdrawal in childhood Morneau-Vaillancourt G; Andlauer TFM; Ouellet-Morin I; Paquin S; Brendgen MR; Vitaro F; Gouin JP; Séguin JR; Gagnon É; Cheesman R; Forget-Dubois N; Rouleau GA; Turecki G; Tremblay RE; Côté SM; Dionne G; Boivin M; 34085288
PSYCHOLOGY
15 Birth weight is associated with adolescent brain development: A multimodal imaging study in monozygotic twins. Hayward DA, Pomares F, Casey KF, Ismaylova E, Levesque M, Greenlaw K, Vitaro F, Brendgen M, Rénard F, Dionne G, Boivin M, Tremblay RE, Booij L 32881198
PSYCHOLOGY
16 mGlu5 receptor availability in youth at risk for addictions: effects of vulnerability traits and cannabis use. Cox SML, Tippler M, Jaworska N, Smart K, Castellanos-Ryan N, Durand F, Allard D, Benkelfat C, Parent S, Dagher A, Vitaro F, Boivin M, Pihl RO, Côté S, Tremblay RE, Séguin JR, Leyton M 32413893
CSBN
17 Extra-striatal D2/3 receptor availability in youth at risk for addiction. Jaworska N, Cox SML, Tippler M, Castellanos-Ryan N, Benkelfat C, Parent S, Dagher A, Vitaro F, Boivin M, Pihl RO, Côté SM, Tremblay RE, Séguin JR, Leyton M 32259831
CSBN
18 Birth weight discordance, DNA methylation, and cortical morphology of adolescent monozygotic twins. Casey KF, Levesque ML, Szyf M, Ismaylova E, Verner MP, Suderman M, Vitaro F, Brendgen M, Dionne G, Boivin M, Tremblay RE, Booij L 28032437
PSYCHOLOGY
19 Serotonin transporter promoter methylation in peripheral cells and neural responses to negative stimuli: A study of adolescent monozygotic twins. Ismaylova E, Lévesque ML, Pomares FB, Szyf M, Nemoda Z, Fahim C, Vitaro F, Brendgen M, Dionne G, Boivin M, Tremblay RE, Booij L 30089832
PSYCHOLOGY
20 Effect of (Z)-isomer content on [11C]ABP688 binding potential in humans. Smart K, Cox SML, Kostikov A, Shalai A, Scala SG, Tippler M, Jaworska N, Boivin M, Séguin JR, Benkelfat C, Leyton M 30607444
CSBN
21 Sex differences in [11C]ABP688 binding: a positron emission tomography study of mGlu5 receptors. Smart K, Cox SML, Scala SG, Tippler M, Jaworska N, Boivin M, Séguin JR, Benkelfat C, Leyton M 30627817
CSBN

 

Title:Effect of (Z)-isomer content on [11C]ABP688 binding potential in humans.
Authors:Smart KCox SMLKostikov AShalai AScala SGTippler MJaworska NBoivin MSéguin JRBenkelfat CLeyton M
Link:https://www.ncbi.nlm.nih.gov/pubmed/30607444?dopt=Abstract
Publication:
Keywords:
PMID:30607444 Category:Eur J Nucl Med Mol Imaging Date Added:2019-05-31
Dept Affiliation: CSBN
1 Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC, H3A 1A1, Canada. kelly.smart@mail.mcgill.ca.
2 Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC, H3A 1A1, Canada.
3 Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC, H3A 2B4, Canada.
4 McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, QC, H3A 2B4, Canada.
5 Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, K1H 8M5, Canada.
6 Institute of Mental Health Research, affiliated with the University of Ottawa, Ottawa, ON, K1Z 7K4, Canada.
7 Department of Psychology, Université Laval, Laval, QC, G1V 0A6, Canada.
8 CHU Ste-Justine Research Center, Montreal, QC, H3T 1C5, Canada.
9 Department of Psychiatry and Addiction, Université de Montréal, Montreal, QC, H3T 1J4, Canada.
10 Department of Psychology, McGill University, Montreal, QC, H3G 1G1, Canada.
11 Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, QC, H4B 1R6, Canada.

Description:

Effect of (Z)-isomer content on [11C]ABP688 binding potential in humans.

Eur J Nucl Med Mol Imaging. 2019 May;46(5):1175-1178

Authors: Smart K, Cox SML, Kostikov A, Shalai A, Scala SG, Tippler M, Jaworska N, Boivin M, Séguin JR, Benkelfat C, Leyton M

Abstract

PURPOSE: To determine how the low-affinity (Z)-isomer of the radiotracer [11C]ABP688 affects binding potential values in vivo in humans.

METHODS: High-resolution [11C]ABP688 PET scans were acquired on 74 healthy volunteers (25 male, 49 female, mean age 20?±?3.0). The relative contents of (E)- and (Z)-isomers were determined prior to injection using analytical high-performance liquid chromatography [rt(E)?=?10 min, rt(Z)?=?8.5 min]. Mean binding potential [BPND?=?fND * (Bavail/KD)] values were calculated in the striatum, limbic regions, and prefrontal cortex using the simplified reference tissue model with cerebellar grey matter as reference.

RESULTS: Mean?±?SD (E)-isomer content in [11C]ABP688 production was 92?±?3.8% (range 78-97%). Percent (E)-isomer was positively correlated with BPND in the striatum (??=?0.28, p?=?0.015) and limbic regions (??=?0.25, p?=?0.036). In multiple regression analysis, sex (ß?=?0.39, p?=?0.001) and (E)-isomer content (ß?=?0.23, p?=?0.040) were significant predictors of BPND.

CONCLUSIONS: Even modest levels of (Z)-[11C]ABP688 can reduce estimates of tracer binding in vivo. Future studies should use production methods that enrich levels of (E)-[11C]ABP688, report tracer isomer ratios, and account for this factor in their analyses.

PMID: 30607444 [PubMed - in process]





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