Keyword search (4,163 papers available)

"Boivin M" Authored Publications:

Title Authors PubMed ID
1 Correction: Polygenic scores of obesity in childhood based on summary statistics from adults versus children Goulet D; Boivin M; Gravel C; Little J; Ouellet-Morin I; Gouin J; Dubois L; 41182116
CONCORDIA
2 Trajectories of childhood eating behaviors and their association with internalizing and externalizing symptoms in adolescence Dufour R; Breton É; Côté SM; Dubois L; Vitaro F; Boivin M; Tremblay RE; Booij L; 40883733
PSYCHOLOGY
3 Polygenic scores of obesity in childhood based on summary statistics from adults vs. children Goulet D; Boivin M; Gravel C; Little J; Ouellet-Morin I; Gouin JP; Dubois L; 40132211
CONCORDIA
4 Association between aggression and ADHD polygenic scores and school-age aggression: the mediating role of preschool externalizing behaviors and adverse experiences Bouliane M; Boivin M; Kretschmer T; Lafreniere B; Paquin S; Tremblay R; Côté S; Gouin JP; Andlauer TFM; Petitclerc A; Ouellet-Morin I; 39907790
PSYCHOLOGY
5 A multimodal neuroimaging study of youth at risk for substance use disorders: Functional magnetic resonance imaging and [18F]fallypride positron emission tomography Nikolic M; Cox SML; Jaworska N; Castellanos-Ryan N; Dagher A; Vitaro F; Brendgen M; Parent S; Boivin M; Côté S; Tremblay RE; Séguin JR; Leyton M; 39725679
CSBN
6 Prediction of depressive symptoms in young adults by polygenic score and childhood maltreatment: Results from a population-based birth cohort Scardera S; Geoffroy MC; Langevin R; Perret LC; Collin-Vézina D; Voronin I; Gouin JP; Meng X; Boivin M; Ouellet-Morin I; 39465601
PSYCHOLOGY
7 Childhood hyperactivity, eating behaviours, and executive functions: Their association with the development of eating-disorder symptoms in adolescence Dufour R; Breton É; Morin AJS; Côté SM; Dubois L; Vitaro F; Boivin M; Tremblay RE; Booij L; 37833803
PSYCHOLOGY
8 Childhood Overeating and Disordered Eating From Early Adolescence to Young Adulthood: A Longitudinal Study on the Mediating Role of BMI, Victimization and Desire for Thinness Breton É; Côté SM; Dubois L; Vitaro F; Boivin M; Tremblay RE; Booij L; 37270466
PSYCHOLOGY
9 Adolescent anxiety and pain problems: A joint, genome-wide investigation and pathway-based analysis Mascheretti S; Forni D; Lampis V; Fumagalli L; Paquin S; Andlauer TFM; Wang W; Dionne G; Brendgen MR; Vitaro F; Ouellet-Morin I; Rouleau G; Gouin JP; Côté S; Tremblay RE; Turecki G; Garon-Carrier G; Boivin M; Battaglia M; 37146008
PSYCHOLOGY
10 Depression, anxiety, and suicidal ideation in a population-based cohort of young adults before and during the first 12 months of the COVID-19 pandemic in Canada Gouin JP; MacNeil S; de la Torre-Luque A; Chartrand E; Chadi N; Rouquette A; Boivin M; Côté S; Geoffroy MC; 37093498
PSYCHOLOGY
11 Pathways of association between disordered eating in adolescence and mental health outcomes in young adulthood during the COVID-19 pandemic Loose T; Geoffroy MC; Orri M; Chadi N; Scardera S; Booij L; Breton E; Tremblay R; Boivin M; Coté S; 36482144
PSYCHOLOGY
12 Developmental trajectories of eating disorder symptoms: A longitudinal study from early adolescence to young adulthood Breton É; Dufour R; Côté SM; Dubois L; Vitaro F; Boivin M; Tremblay RE; Booij L; 35725645
PSYCHOLOGY
13 Depression and anxiety symptoms in young adults before and during the COVID-19 pandemic: evidence from a Canadian population-based cohort Watkins-Martin K; Orri M; Pennestri MH; Castellanos-Ryan N; Larose S; Gouin JP; Ouellet-Morin I; Chadi N; Philippe F; Boivin M; Tremblay RE; Côté S; Geoffroy MC; 34496901
PSYCHOLOGY
14 Polygenic scores differentially predict developmental trajectories of subtypes of social withdrawal in childhood Morneau-Vaillancourt G; Andlauer TFM; Ouellet-Morin I; Paquin S; Brendgen MR; Vitaro F; Gouin JP; Séguin JR; Gagnon É; Cheesman R; Forget-Dubois N; Rouleau GA; Turecki G; Tremblay RE; Côté SM; Dionne G; Boivin M; 34085288
PSYCHOLOGY
15 Birth weight is associated with adolescent brain development: A multimodal imaging study in monozygotic twins. Hayward DA, Pomares F, Casey KF, Ismaylova E, Levesque M, Greenlaw K, Vitaro F, Brendgen M, Rénard F, Dionne G, Boivin M, Tremblay RE, Booij L 32881198
PSYCHOLOGY
16 mGlu5 receptor availability in youth at risk for addictions: effects of vulnerability traits and cannabis use. Cox SML, Tippler M, Jaworska N, Smart K, Castellanos-Ryan N, Durand F, Allard D, Benkelfat C, Parent S, Dagher A, Vitaro F, Boivin M, Pihl RO, Côté S, Tremblay RE, Séguin JR, Leyton M 32413893
CSBN
17 Extra-striatal D2/3 receptor availability in youth at risk for addiction. Jaworska N, Cox SML, Tippler M, Castellanos-Ryan N, Benkelfat C, Parent S, Dagher A, Vitaro F, Boivin M, Pihl RO, Côté SM, Tremblay RE, Séguin JR, Leyton M 32259831
CSBN
18 Birth weight discordance, DNA methylation, and cortical morphology of adolescent monozygotic twins. Casey KF, Levesque ML, Szyf M, Ismaylova E, Verner MP, Suderman M, Vitaro F, Brendgen M, Dionne G, Boivin M, Tremblay RE, Booij L 28032437
PSYCHOLOGY
19 Serotonin transporter promoter methylation in peripheral cells and neural responses to negative stimuli: A study of adolescent monozygotic twins. Ismaylova E, Lévesque ML, Pomares FB, Szyf M, Nemoda Z, Fahim C, Vitaro F, Brendgen M, Dionne G, Boivin M, Tremblay RE, Booij L 30089832
PSYCHOLOGY
20 Effect of (Z)-isomer content on [11C]ABP688 binding potential in humans. Smart K, Cox SML, Kostikov A, Shalai A, Scala SG, Tippler M, Jaworska N, Boivin M, Séguin JR, Benkelfat C, Leyton M 30607444
CSBN
21 Sex differences in [11C]ABP688 binding: a positron emission tomography study of mGlu5 receptors. Smart K, Cox SML, Scala SG, Tippler M, Jaworska N, Boivin M, Séguin JR, Benkelfat C, Leyton M 30627817
CSBN

 

Title:Polygenic scores of obesity in childhood based on summary statistics from adults vs. children
Authors:Goulet DBoivin MGravel CLittle JOuellet-Morin IGouin JPDubois L
Link:https://pubmed.ncbi.nlm.nih.gov/40132211/
DOI:10.1139/cjpp-2024-0221
Publication:Canadian journal of physiology and pharmacology
Keywords:
PMID:40132211 Category: Date Added:2025-03-25
Dept Affiliation: CONCORDIA
1 University of Ottawa, Ottawa, Ontario, Canada; dgoul082@uottawa.ca.
2 Université Laval, Quebec City, Canada; michel.boivin@psy.ulaval.ca.
3 University of Ottawa, Ottawa, Canada.
4 McGill University, Department of Epidemiology, Biostatistics and Occupational Health, Montreal, Canada.
5 University of Ottawa, Department of Mathematics and Statistics, Ottawa, Canada; cgravel@uottawa.ca.
6 University of Ottawa, Epidemiology & Community Medicine, Ottawa, Ontario, Canada.
7 Canada Research Chair in Human Genome Epidemiology, Ottawa, Ontario, Canada; jlittle@uottawa.ca.
8 Université de Montréal, Montreal, Canada; isabelle.ouellet-morin@umontreal.ca.
9 Université Concordia, Département de psychologie, Montreal, Canada; JP.Gouin@concordia.ca.
10 University of Ottawa, Ottawa, Canada; ldubois@uottawa.ca.

Description:

The lack of polygenic scores (PGSs) developed for body-mass index (BMI) in children may be problematic because the genetic architecture characterizing BMI changes throughout life. This study aims to describe the genetic susceptibility to obesity in children and to compare two PGSs based on data from adults and children and their association with BMI and discrimination of obesity. The study sample comprises 717 participants aged 4 to 13. Adult- and child-based PGS were evaluated by examining 1) mean BMI across polygenic score risk categories, 2) the capacity to identify obesity with logistic regression and 3) the linear association with BMI z-scores using linear regression. Increases in one standardized unit of adult-based PGS were related to a stronger increase in BMI z-score (ß=0.24-0.39) than PGS derived in children (ß=0.21-0.30). The association between obesity and the child score was higher (OR = 1.75-2.33) than for the adult score (OR = 1.74-2.06) for the age group 4-7 years. The inverse was observed for the age group 8-13 years (ORchild 1.56-1.79 vs. ORadult 1.78-2.54). Both adult- and child-based PGS show strong associations with BMI and risk of obesity, with the adult-based score standing out from 8 years old.





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