Keyword search (4,163 papers available)

"Liu-Ambrose T" Authored Publications:

Title Authors PubMed ID
1 Probing cognitive reserve with resting state functional connectivity in subcortical ischemic vascular cognitive impairment Gu Y; Hsu CL; Boa Sorte Silva NC; Tam RC; Alkeridy WA; Lam K; Liu-Ambrose T; 41929984
HKAP
2 Resistance training and subcortical vascular cognitive impairment: A 12-month randomized trial Liu-Ambrose T; Falck RS; Dao E; Crockett RA; Barha CK; Silva NCBS; Alkeridy WA; Best JR; Hsiung GR; Field TS; Madden KM; Davis JC; Ten Brinke LF; Tam RC; 41795685
HKAP
3 The effect of hearing ability on dual-task performance following multi-domain training in older adults with mild cognitive impairment: findings from the SYNERGIC trial Downey RI; Petersen BJ; Mohanathas N; Campos JL; Montero-Odasso M; Bherer L; Pichora-Fuller MK; Bray NW; Burhan AM; Camicioli R; Fraser S; Liu-Ambrose T; Lussier M; Middleton LE; Pieruccini-Faria F; Phillips NA; Li KZH; 41694460
SOH
4 Intra-individual variability in cognitive performance predicts falls in older adults with chronic stroke Dimri V; Davis JC; Boa Sorte Silva NC; Balbim GM; Eng JJ; Liu-Ambrose T; 41474479
HKAP
5 Dementia Care Research and Psychosocial Factors Mancor E; Montero-Odasso M; Bherer L; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Li K; 41448628
CONCORDIA
6 Clinical Manifestations Gagnon C; Montero-Odasso M; Zou G; Speechley MR; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Bray NW; Li K; Fraser S; Pieruccini-Faria F; Burhan AM; Berryman N; Lussier M; Son S; Shoemaker JK; Bherer L; 41447475
CONCORDIA
7 Developing Topics Silva NCBS; Stein RG; Gu Y; Hsu CL; Tam RC; Salluzzi M; McCreary CR; Alkeridy WA; Lam K; MacKay AL; Kolind S; Cossette B; Griffith LE; Hogan DB; McMillan JM; Raina P; Smith EE; Liu-Ambrose T; 41434542
CONCORDIA
8 Public Health Silva NCBS; Balbim GM; Stein RG; Gu Y; Tam RC; Dao E; Alkeridy WA; Kramer AF; Liu-Ambrose T; 41435075
CONCORDIA
9 Public Health Pieruccini-Faria F; Son S; Liu-Ambrose T; Burhan AM; Almeida QJ; Middleton LE; Li K; Fraser S; Bherer L; Montero-Odasso M; 41435121
CONCORDIA
10 Synergistic effects of exercise, cognitive training and vitamin D on gait performance and falls in mild cognitive impairment-secondary outcomes from the SYNERGIC trial Pieruccini-Faria F; Son S; Zou G; Almeida QJ; Middleton LE; Bray NW; Lussier M; Shoemaker JK; Speechley M; Liu-Ambrose T; Burhan AM; Camicioli R; Li KZH; Fraser S; Berryman N; Bherer L; Montero-Odasso M; 40966614
SOH
11 24-hour activity cycle behaviors and gray matter volume in mild cognitive impairment Balbim GM; Boa Sorte Silva NC; Falck RS; Kramer AF; Voss MW; Liu-Ambrose T; 40693459
HKAP
12 Physical activity may protect myelin via modulation of high-density lipoprotein Boa Sorte Silva NC; Balbim GM; Stein RG; Gu Y; Tam RC; Dao E; Alkeridy W; Lam K; Kramer AF; Liu-Ambrose T; 39989020
HKAP
13 Effects of Exercise Alone or Combined With Cognitive Training and Vitamin D Supplementation to Improve Cognition in Adults With Mild Cognitive Impairment: A Randomized Clinical Trial Montero-Odasso M; Zou G; Speechley M; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Bray NW; Li KZH; Fraser S; Pieruccini-Faria F; Berryman N; Lussier M; Shoemaker JK; Son S; Bherer L; 37471089
PERFORM
14 Guidelines for Gait Assessments in the Canadian Consortium on Neurodegeneration in Aging (CCNA). Cullen S, Montero-Odasso M, Bherer L, Almeida Q, Fraser S, Muir-Hunter S, Li K, Liu-Ambrose T, McGibbon CA, McIlroy W, Middleton LE, Sarquis-Adamson Y, Beauchet O, McFadyen BJ, Morais JA, Camicioli R, Canadian Gait and Cognition Network 29977431
ENCS
15 SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment. Montero-Odasso M, Almeida QJ, Burhan AM, Camicioli R, Doyon J, Fraser S, Li K, Liu-Ambrose T, Middleton L, Muir-Hunter S, McIlroy W, Morais JA, Pieruccini-Faria F, Shoemaker K, Speechley M, Vasudev A, Zou GY, Berryman N, Lussier M, Vanderhaeghe L, Bherer L 29661156
PERFORM
16 Consensus on Shared Measures of Mobility and Cognition: From the Canadian Consortium on Neurodegeneration in Aging (CCNA). Montero-Odasso M, Almeida QJ, Bherer L, Burhan AM, Camicioli R, Doyon J, Fraser S, Muir-Hunter S, Li KZH, Liu-Ambrose T, McIlroy W, Middleton L, Morais JA, Sakurai R, Speechley M, Vasudev A, Beauchet O, Hausdorff JM, Rosano C, Studenski S, Verghese J, Canadian Gait and Cognition Network 30101279
PERFORM
17 Brain gray matter volume associations with gait speed and related structural covariance networks in cognitively healthy individuals and in patients with mild cognitive impairment: A cross-sectional study. Beauchet O, Montembeault M, Barden JM, Szturm T, Bherer L, Liu-Ambrose T, Chester VL, Li K, Helbostad JL, Allali G, Canadian Gait Consortium 31075383
PSYCHOLOGY
18 A review of the effects of physical activity and exercise on cognitive and brain functions in older adults. Bherer L, Erickson KI, Liu-Ambrose T 24102028
PERFORM
19 Physical exercise and brain functions in older adults. Bherer L, Erickson KI, Liu-Ambrose T 24163767
PERFORM
20 Anti-Dementia Drugs, Gait Performance and Mental Imagery of Gait: A Non-Randomized Open-Label Trial. Beauchet O, Barden J, Liu-Ambrose T, Chester VL, Annweiler C, Szturm T, Grenier S, Léonard G, Bherer L, Allali G, Canadian Gait Consortium 27568453
PERFORM
21 Association Between Falls and Brain Subvolumes: Results from a Cross-Sectional Analysis in Healthy Older Adults. Beauchet O, Launay CP, Barden J, Liu-Ambrose T, Chester VL, Szturm T, Grenier S, Léonard G, Bherer L, Annweiler C, Helbostad JL, Verghese J, Allali G, Biomathics and Canadian Gait Consortium 27785698
PERFORM

 

Title:Intra-individual variability in cognitive performance predicts falls in older adults with chronic stroke
Authors:Dimri VDavis JCBoa Sorte Silva NCBalbim GMEng JJLiu-Ambrose T
Link:https://pubmed.ncbi.nlm.nih.gov/41474479/
DOI:10.1007/s40520-025-03287-y
Publication:Aging clinical and experimental research
Keywords:Chronic strokeCognitionFallsIntra-individual variabilityReaction time
PMID:41474479 Category: Date Added:2025-12-31
Dept Affiliation: HKAP
1 Aging, Mobility, and Cognitive Health Laboratory, University of British Columbia, Vancouver, BC, Canada.
2 Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada.
3 Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
4 Centre for Aging SMART at Vancouver Coastal Health, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.
5 Faculty of Management, University of British Columbia Okanagan, Kelowna, BC, Canada.
6 Department of Kinesiology, Health, and Applied Physiology, Concordia University, Montreal, QC, Canada.
7 Aging, Mobility, and Cognitive Health Laboratory, University of British Columbia, Vancouver, BC, Canada. teresa.ambrose@ubc.ca.
8 Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada. teresa.ambrose@ubc.ca.
9 Centre for Aging SMART at Vancouver Coastal Health, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada. teresa.ambrose@ubc.ca.
10 Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada. teresa.ambrose@ubc.ca.
11 Djavad Mowafaghian Centre for Brain Health, c/o Liu-Ambrose Lab, 2215 Wesbrook Mall, Vancouver, BC, V6T 2B5, Canada. teresa.ambrose@ubc.ca.

Description:

Background: Common consequences of a stroke include impaired motor and cognitive function, with both being linked to increased falls and frailty. Intra-individual variability (IIV) of cognitive performance, which refers to the within-person trial-to-trial variation in reaction time during cognitive tasks, may be a useful predictor for falls in older adults with chronic stroke.

Objective: To examine whether IIV or "traditional" reaction time (RT) measures of cognitive performance predict falls in older adults with chronic stroke.

Methods: This study is a secondary analysis of a proof-of-concept randomized controlled trial (RCT) among community-dwelling adults with a history of stroke, aged 55 years and older, able to walk 6 m, and without dementia. Residualised intraindividual standard deviation (rISD) was the measure of IIV and mean RT was the "traditional" measure of performance on a computerised Stroop Task. Falls were tracked and adjudicated over six months.

Results: 120 participants with a mean (SD) age of 70 (8) years, and 46 (38%) female participants, experienced a mean of 0.61 (SD = 1.15) falls over 6 months. rISD for the congruent Stroop Task condition predicted falls, such that a one-unit increase was associated with 20.5% increase in fall rate.

Conclusion: The findings suggest that IIV metrics may have the potential in fall risk screening post-stroke. Further research is required to evaluate whether IIV in cognitive performance can be improved via interventions such as cognitive training and physical activity.





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