Keyword search (4,164 papers available)

"Ma C" Authored Publications:

Title Authors PubMed ID
1 Crowd Counting Using Meta-Test-Time Adaptation Ma C; Neri F; Gu L; Wang Z; Wang J; Qing A; Wang Y; 39252679
ENCS
2 Revisiting Homochiral versus Heterochiral Interactions through a Long Detective Story of a Useful Azobis-Nitrile and Puzzling Racemate García de la Concepción J; Flores-Jiménez M; Cuccia LA; Light ME; Viedma C; Cintas P; 37547876
CHEMBIOCHEM
3 On the Origin of Sugar Handedness: Facts, Hypotheses and Missing Links-A Review Martínez RF; Cuccia LA; Viedma C; Cintas P; 35796896
CHEMBIOCHEM
4 Empowering Melatonin Therapeutics with Drosophila Models Millet-Boureima C; Ennis CC; Jamison J; McSweeney S; Park A; Gamberi C; 34698120
BIOLOGY
5 The Biology of Vasopressin. Sparapani S, Millet-Boureima C, Oliver J, Mu K, Hadavi P, Kalostian T, Ali N, Avelar CM, Bardies M, Barrow B, Benedikt M, Biancardi G, Bindra R, Bui L, Chihab Z, Cossitt A, Costa J, Daigneault T, Dault J, Davidson I, Dias J, Dufour E, El-Khoury S, Farhangdoost N, Forget A, Fox A, Gebrael M, Gentile MC, Geraci O, Gnanapragasam A, Gomah E, Haber E, Hamel C, Iyanker T, Kalantzis C, Kamali S, Kassardjian E, Kontos HK, Le TBU, LoScerbo D, Low YF, Mac Rae D, Maurer F, Mazhar S, Nguyen A, Nguyen-Duong K, Osborne-L 33477721
BIOLOGY
6 Cyst Reduction by Melatonin in a Novel Drosophila Model of Polycystic Kidney Disease. Millet-Boureima C; Rozencwaig R; Polyak F; Gamberi C; 33238462
BIOLOGY
7 Drug discovery and chemical probing in Drosophila. Millet-Boureima C, Selber-Hnatiw S, Gamberi C 32551911
BIOLOGY
8 Pasteur made simple - mechanochemical transformation of racemic amino acid crystals into racemic conglomerate crystals. Viedma C, Lennox C, Cuccia LA, Cintas P, Ortiz JE 32202285
NA
9 Cyst Reduction in a Polycystic Kidney Disease Drosophila Model Using Smac Mimics. Millet-Boureima C, Chingle R, Lubell WD, Gamberi C 31635379
BIOLOGY
10 Modeling Renal Disease "On the Fly". Millet-Boureima C, Porras Marroquin J, Gamberi C 29955604
BIOLOGY
11 Oriented attachment by enantioselective facet recognition in millimeter-sized gypsum crystals. Viedma C, Cuccia LA, McTaggart A, Kahr B, Martin AT, McBride JM, Cintas P 27722508
CHEMBIOCHEM

 

Title:Drug discovery and chemical probing in Drosophila.
Authors:Millet-Boureima CSelber-Hnatiw SGamberi C
Link:https://www.ncbi.nlm.nih.gov/pubmed/32551911?dopt=Abstract
DOI:10.1139/gen-2020-0037
Publication:Genome
Keywords:Drosophilacriblage de composésdrug discoverydrug screenscouverte de médicamentsmaladies orphelinesmodèles animauxorphan diseasepathway probingpolycystic kidney diseasepolykystose rénalesondage des sentierswhole-animal models
PMID:32551911 Category:Genome Date Added:2020-06-20
Dept Affiliation: BIOLOGY
1 Biology Department, Concordia University, Montreal, QC H4B 1R6, Canada.

Description:

Drug discovery and chemical probing in Drosophila.

Genome. 2020 Jun 18;:

Authors: Millet-Boureima C, Selber-Hnatiw S, Gamberi C

Abstract

Flies are increasingly utilized in drug discovery and chemical probing in vivo, which are novel technologies complementary to genetic probing in fundamental biological studies. Excellent genetic conservation, small size, short generation time and over one hundred years of genetics make Drosophila an attractive model for rapid assay readout and use of analytical amounts of compound, enabling the experimental iterations needed in early drug development at a fraction of time and costs. Here, we describe an effective drug-testing pipeline using adult flies that can be easily implemented to study several disease models and different genotypes to discover novel molecular insight, probes, quality lead compounds, and develop novel prototype drugs.

PMID: 32551911 [PubMed - as supplied by publisher]





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