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PubMed Publications| Keyword search (4,163 papers available) |  |
"Ma C" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Crowd Counting Using Meta-Test-Time Adaptation | Ma C; Neri F; Gu L; Wang Z; Wang J; Qing A; Wang Y; | 39252679 ENCS |
| 2 | Revisiting Homochiral versus Heterochiral Interactions through a Long Detective Story of a Useful Azobis-Nitrile and Puzzling Racemate | García de la Concepción J; Flores-Jiménez M; Cuccia LA; Light ME; Viedma C; Cintas P; | 37547876 CHEMBIOCHEM |
| 3 | On the Origin of Sugar Handedness: Facts, Hypotheses and Missing Links-A Review | Martínez RF; Cuccia LA; Viedma C; Cintas P; | 35796896 CHEMBIOCHEM |
| 4 | Empowering Melatonin Therapeutics with Drosophila Models | Millet-Boureima C; Ennis CC; Jamison J; McSweeney S; Park A; Gamberi C; | 34698120 BIOLOGY |
| 5 | The Biology of Vasopressin. | Sparapani S, Millet-Boureima C, Oliver J, Mu K, Hadavi P, Kalostian T, Ali N, Avelar CM, Bardies M, Barrow B, Benedikt M, Biancardi G, Bindra R, Bui L, Chihab Z, Cossitt A, Costa J, Daigneault T, Dault J, Davidson I, Dias J, Dufour E, El-Khoury S, Farhangdoost N, Forget A, Fox A, Gebrael M, Gentile MC, Geraci O, Gnanapragasam A, Gomah E, Haber E, Hamel C, Iyanker T, Kalantzis C, Kamali S, Kassardjian E, Kontos HK, Le TBU, LoScerbo D, Low YF, Mac Rae D, Maurer F, Mazhar S, Nguyen A, Nguyen-Duong K, Osborne-L | 33477721 BIOLOGY |
| 6 | Cyst Reduction by Melatonin in a Novel Drosophila Model of Polycystic Kidney Disease. | Millet-Boureima C; Rozencwaig R; Polyak F; Gamberi C; | 33238462 BIOLOGY |
| 7 | Drug discovery and chemical probing in Drosophila. | Millet-Boureima C, Selber-Hnatiw S, Gamberi C | 32551911 BIOLOGY |
| 8 | Pasteur made simple - mechanochemical transformation of racemic amino acid crystals into racemic conglomerate crystals. | Viedma C, Lennox C, Cuccia LA, Cintas P, Ortiz JE | 32202285 NA |
| 9 | Cyst Reduction in a Polycystic Kidney Disease Drosophila Model Using Smac Mimics. | Millet-Boureima C, Chingle R, Lubell WD, Gamberi C | 31635379 BIOLOGY |
| 10 | Modeling Renal Disease "On the Fly". | Millet-Boureima C, Porras Marroquin J, Gamberi C | 29955604 BIOLOGY |
| 11 | Oriented attachment by enantioselective facet recognition in millimeter-sized gypsum crystals. | Viedma C, Cuccia LA, McTaggart A, Kahr B, Martin AT, McBride JM, Cintas P | 27722508 CHEMBIOCHEM |
| Title: | Empowering Melatonin Therapeutics with Drosophila Models | ||||
| Authors: | Millet-Boureima C, Ennis CC, Jamison J, McSweeney S, Park A, Gamberi C | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/34698120/ | ||||
| DOI: | 10.3390/diseases9040067 | ||||
| Publication: | Diseases (Basel, Switzerland) | ||||
| Keywords: | Drosophila; PKD; longevity; melatonin; neurodegeneration; oxidative stress; | ||||
| PMID: | 34698120 | Category: | Date Added: | 2021-10-26 | |
| Dept Affiliation: |
BIOLOGY
1 Biology Department, Concordia University, Montreal, QC H4B 1R6, Canada. 2 Department of Biology, Coastal Carolina University, Conway, SC 29528-6054, USA. |
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Description: |
Melatonin functions as a central regulator of cell and organismal function as well as a neurohormone involved in several processes, e.g., the regulation of the circadian rhythm, sleep, aging, oxidative response, and more. As such, it holds immense pharmacological potential. Receptor-mediated melatonin function mainly occurs through MT1 and MT2, conserved amongst mammals. Other melatonin-binding proteins exist. Non-receptor-mediated activities involve regulating the mitochondrial function and antioxidant cascade, which are frequently affected by normal aging as well as disease. Several pathologies display diseased or dysfunctional mitochondria, suggesting melatonin may be used therapeutically. Drosophila models have extensively been employed to study disease pathogenesis and discover new drugs. Here, we review the multiple functions of melatonin through the lens of functional conservation and model organism research to empower potential melatonin therapeutics to treat neurodegenerative and renal diseases. |
