Keyword search (4,163 papers available)

"Skinner CD" Authored Publications:

Title Authors PubMed ID
1 Luminescent Electro-Spun Nanofibers Crosslinked with Boronic Esters Exhibiting Controlled Release of Carbon Dots for Detection of Wound pHs and Enhanced Antimicrobial Lokuge ND; Casillas-Popova SN; Singh P; Clermont-Paquette A; Skinner CD; Findlay BL; Naccache R; Oh JK; 40920389
BIOLOGY
2 Multi-stimuli-responsive degradable boronic ester-crosslinked e-spun nanofiber wound dressings Casillas-Popova SN; Lokuge ND; Singh P; Cirillo A; Thinphang-Nga A; Skinner CD; Vuckovic D; Findlay BL; Oh JK; 40557709
BIOLOGY
3 pH-Responsive Degradable Electro-Spun Nanofibers Crosslinked via Boronic Ester Chemistry for Smart Wound Dressings Casillas-Popova SN; Lokuge ND; Andrade-Gagnon B; Chowdhury FR; Skinner CD; Findlay BL; Oh JK; 38989606
BIOLOGY
4 A threshold LC-MS/MS method for 92 analytes in oral fluid collected with the Quantisal® device Desharnais B; Lajoie MJ; Laquerre J; Mireault P; Skinner CD; 33035929
CHEMBIOCHEM
5 The Key Role of Intrinsic Lifetime Dynamics from Upconverting Nanosystems in Multiemission Particle Velocimetry Tessitore G; Maurizio SL; Sabri T; Skinner CD; Capobianco JA; 32924221
CNSR
6 Qualitative threshold method validation and uncertainty evaluation: A theoretical framework and application to a 40 analytes liquid chromatography-tandem mass spectrometry method Camirand Lemyre F; Desharnais B; Laquerre J; Morel MA; Côté C; Mireault P; Skinner CD; 32476284
CHEMBIOCHEM
7 Capillary electrochromatography of peptides and proteins. Bandilla D, Skinner CD 15354432
CHEMBIOCHEM
8 Design and optimization of porous polymer enzymatic digestors for proteomics. Lin W, Skinner CD 19575382
CHEMBIOCHEM
9 Increased oxidative modifications of amniotic fluid albumin in pregnancies associated with gestational diabetes mellitus. Boisvert MR, Koski KG, Skinner CD 20063865
CHEMBIOCHEM
10 A case of fatal idiosyncratic reaction to the designer drug 3,4-methylenedioxypyrovalerone (MDPV) and review of the literature. Desharnais B, Dazé Y, Huppertz LM, Mireault P, Skinner CD 28668987
CHEMBIOCHEM
11 A Tool for Automatic Correction of Endogenous Concentrations: Application to BHB Analysis by LC-MS-MS and GC-MS Desharnais B; Lajoie MJ; Laquerre J; Savard S; Mireault P; Skinner CD; 31141151
CHEMBIOCHEM

 

Title:A case of fatal idiosyncratic reaction to the designer drug 3,4-methylenedioxypyrovalerone (MDPV) and review of the literature.
Authors:Desharnais B,  Dazé Y,  Huppertz LM,  Mireault P,  Skinner CD
Link:https://www.ncbi.nlm.nih.gov/pubmed/28668987?dopt=Abstract
Publication:
Keywords:
PMID:28668987 Category:Forensic Sci Med Pathol Date Added:2019-05-31
Dept Affiliation: CHEMBIOCHEM
1 Department of Forensic Pathology and Toxicology, Laboratoire de sciences judiciaires et de médecine légale, , 1701 rue Parthenais, Montréal, Québec, H2K 3S7, Canada. brigitte.desharnais@msp.gouv.qc.ca.
2 Department of Chemistry & Biochemistry, Concordia University, 7141 Sherbrooke Street West, Montréal, Québec, H4B 1R6, Canada. brigitte.desharnais@msp.gouv.qc.ca.
3 Department of Forensic Pathology and Toxicology, Laboratoire de sciences judiciaires et de médecine légale, , 1701 rue Parthenais, Montréal, Québec, H2K 3S7, Canada.
4 Institute of Forensic Medicine, Department of Forensic Toxicology, Medical Center, Faculty of Medicine, University of Freiburg, Albertstrasse 9, 79104, Freiburg, Germany.
5 Department of Chemistry & Biochemistry, Concordia University, 7141 Sherbrooke Street West, Montréal, Québec, H4B 1R6, Canada.

Description:

A case of fatal idiosyncratic reaction to the designer drug 3,4-methylenedioxypyrovalerone (MDPV) and review of the literature.

Forensic Sci Med Pathol. 2017 Sep;13(3):350-354

Authors: Desharnais B, Dazé Y, Huppertz LM, Mireault P, Skinner CD

Abstract

The stimulant designer drug 3,4-methylenedioxypyrovalerone (MDPV) was first synthesized by Boehringer Ingelheim in 1969 and introduced on the black market in 2006. Only a small number of fatal intoxication cases have been reported in the literature, all with significant blood MDPV concentrations. In this report, we describe one fatality attributed to an idiosyncratic reaction to MDPV. The victim displayed agitation, violent behavior and delirium followed by cardiac arrest. Hyperthermia was observed at the hospital. The MDPV cardiac and femoral blood concentrations were 6 ng/mL. The presence of excited delirium syndrome and MDPV, a drug with a pharmacology similar to cocaine, leads to the conclusion that the victim suffered a fatal adverse reaction to MDPV. This is the first published case of idiosyncratic reaction to MDPV.

PMID: 28668987 [PubMed - indexed for MEDLINE]




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