Keyword search (4,164 papers available)

"Tam BT" Authored Publications:

Title Authors PubMed ID
1 Combating childhood overweight and obesity: The role of Olympic Movement and bodily movement Tam BT; Wan K; Santosa S; Cai Z; 39991475
SOH
2 Intramyocellular lipid use is altered with exercise in males with childhood-onset obesity despite no differences in substrate oxidation Feola S; Al-Nabelsi L; Tam BT; Near J; Morais JA; Santosa S; 39875595
HKAP
3 Age of obesity onset affects subcutaneous adipose tissue cellularity differently in the abdominal and femoral region Murphy J; Dera A; Morais JA; Tsoukas MA; Khor N; Sazonova T; Almeida LG; Cooke AB; Daskalopoulou SS; Tam BT; Santosa S; 39045668
SOH
4 Senescence markers in subcutaneous preadipocytes differ in childhood- versus adult-onset obesity before and after weight loss Murphy J; Tam BT; Kirkland JL; Tchkonia T; Giorgadze N; Pirtskhalava T; Tsoukas MA; Morais JA; Santosa S; 37194560
PERFORM
5 Sex Affects Regional Variations in Subcutaneous Adipose Tissue T Cells but not Macrophages in Adults with Obesity Murphy J; Delaney KZ; Dam V; Tam BT; Khor N; Tsoukas MA; Morais JA; Santosa S; 33179451
PERFORM
6 Acetyl-CoA regulation, OXPHOS integrity and leptin level are different in females with different onsets of obesity. Tam BT, Murphy J, Khor N, Morais JA, Santosa S 32808657
PERFORM
7 Obestatin and growth hormone reveal the interaction of central obesity and other cardiometabolic risk factors of metabolic syndrome. Yu AP, Ugwu FN, Tam BT, Lee PH, Ma V, Pang S, Chow AS, Cheng KK, Lai CW, Wong CS, Siu PM 32218464
HKAP
8 Obesity and ageing: Two sides of the same coin. Tam BT, Morais JA, Santosa S 32020741
PERFORM
9 Ghrelin Axis Reveals the Interacting Influence of Central Obesity and Hypertension. Yu AP, Ugwu FN, Tam BT, Lee PH, Lai CW, Wong CSC, Siu PM 30258404
HKAP

 

Title:Obestatin and growth hormone reveal the interaction of central obesity and other cardiometabolic risk factors of metabolic syndrome.
Authors:Yu AP,  Ugwu FN,  Tam BT,  Lee PH,  Ma V,  Pang S,  Chow AS,  Cheng KK,  Lai CW,  Wong CS,  Siu PM
Link:https://www.ncbi.nlm.nih.gov/pubmed/32218464?dopt=Abstract
DOI:10.1038/s41598-020-62271-w
Publication:Scientific reports
Keywords:
PMID:32218464 Category:Sci Rep Date Added:2020-03-29
Dept Affiliation: HKAP
1 Division of Kinesiology, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.
2 Department of Health Technology and Informatics, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.
3 Department of Health, Kinesiology and Applied Physiology, Concordia University, Montreal, QC, Canada.
4 School of Nursing, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.
5 Singapore Institute of Technology, Singapore, Singapore.
6 Division of Kinesiology, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. pmsiu@hku.hk.

Description:

Obestatin and growth hormone reveal the interaction of central obesity and other cardiometabolic risk factors of metabolic syndrome.

Sci Rep. 2020 Mar 26;10(1):5495

Authors: Yu AP, Ugwu FN, Tam BT, Lee PH, Ma V, Pang S, Chow AS, Cheng KK, Lai CW, Wong CS, Siu PM

Abstract

Metabolic syndrome (MetS) is a multi-factorial disorder including central obesity (CO), insulin resistance, hyperglycemia, dyslipidemia and hypertension which increases the risk of diabetes mellitus and cardiovascular diseases. CO is considered as an essential component of MetS according to International Diabetes Federation (IDF), which may further modulate distinct signalling pathways compared with the other four MetS risk factors. Given that ghrelin signalling and the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis regulates energy balance and metabolic homeostasis, this study examined the changes in various ghrelin products and circulating hormones in response to the interaction between CO and other MetS components including blood pressure, fasting blood glucose, triglycerides, and high-density lipoprotein cholesterol in 133 Hong Kong Chinese adults. Circulating obestatin and GH were increased and reduced, respectively, by either CO or the other 4-risk factor cluster. These changes were further augmented by the presence of all MetS risk factors. However, changes of ghrelin levels were not mediated by CO but the other MetS risk factors. Our findings suggest that CO does not predict all the dysregulation of signalling pathways in individuals with MetS. Although CO and other MetS may share common signalling targets (i.e., obestatin and GH), CO does not contribute to the perturbation of ghrelin signalling.

PMID: 32218464 [PubMed - as supplied by publisher]




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