Keyword search (4,163 papers available)

"Woodside B" Authored Publications:

Title Authors PubMed ID
1 Effects of maternal mild hyperglycemia associated with snack intake on offspring metabolism and behavior across the lifespan Martins MG; Woodside B; Kiss ACI; 38331375
PSYCHOLOGY
2 Energetic demands of lactation produce an increase in the expression of growth hormone secretagogue receptor in the hypothalamus and ventral tegmental area of the rat despite a reduction in circulating ghrelin Wellman M; Budin R; Woodside B; Abizaid A; 35365872
PSYCHOLOGY
3 Sex differences in developmental patterns of neocortical astroglia: A mouse translatome database Rurak GM; Simard S; Freitas-Andrade M; Lacoste B; Charih F; Van Geel A; Stead J; Woodside B; Green JR; Coppola G; Salmaso N; 35108542
ENCS
4 Effects of snack intake during pregnancy and lactation on reproductive outcome in mild hyperglycemic rats Martins MG; Cruz AGD; Oliveira GP; Woodside B; Horta-Júnior JACE; Kiss ACI; 34332976
PSYCHOLOGY
5 Ghrelin receptor signalling is not required for glucocorticoid-induced obesity in female mice Silver Z; Abbott-Tate S; Hyland L; Sherratt F; Woodside B; Abizaid A; 34060474
CSBN
6 Prefrontal Cortex and Multiparity in Lactation. Opala EA, Verlezza S, Long H, Rusu D, Woodside B, Walker CD 31437474
CSBN
7 Central ghrelin receptor stimulation modulates sex motivation in male rats in a site dependent manner. Hyland L, Rosenbaum S, Edwards A, Palacios D, Graham MD, Pfaus JG, Woodside B, Abizaid A 29080670
CSBN
8 Gating of the neuroendocrine stress responses by stressor salience in early lactating female rats is independent of infralimbic cortex activation and plasticity. Hillerer KM, Woodside B, Parkinson E, Long H, Verlezza S, Walker CD 29397787
CSBN
9 Reduction and S-nitrosation of the neuropeptide oxytocin: implications for its biological function Roy JF; Chrétien MN; Woodside B; English AM; 17692543
CBAMS
10 Food restriction during lactation suppresses Kiss1 mRNA expression and kisspeptin-stimulated LH release in rats. Ladyman SR, Woodside B 24492858
CSBN
11 Physiological mechanisms, behavioral and psychological factors influencing the transfer of milk from mothers to their young. Jonas W, Woodside B 26232032
CSBN
12 Mood, Food, and Fertility: Adaptations of the Maternal Brain. Woodside B 27347899
PSYCHOLOGY

 

Title:Reduction and S-nitrosation of the neuropeptide oxytocin: implications for its biological function
Authors:Roy JF,  Chrétien MN,  Woodside B,  English AM
Link:https://pubmed.ncbi.nlm.nih.gov/17692543/
DOI:10.1016/j.niox.2007.06.005
Publication:Nitric oxide : biology and chemistry
Keywords:
PMID:17692543 Category:Nitric Oxide Date Added:2019-06-19
Dept Affiliation: CBAMS
1 Department of Chemistry and Biochemistry, Centre for Biological Applications of Mass Spectrometry, Concordia University, 7141 Sherbrooke Street W., Montreal, Que., Canada.

Description:

Oxytocin (OT; Cys-Tyr-Ile-Gln-Asn-Cys-Pro-leu-Gly), a posterior pituitary peptide hormone, is characterized by a Cys1-Cys6 disulfide bond in its stable, isolated state. This paper describes a simple, one-step method for the production of OT in its reduced, dithiol form (OT dithiol), free of reducing agent. The effects of temperature, pH, and metal-ion chelators on the autoxidation of OT dithiol were examined to establish if this form is likely to persist under biological conditions. It was found that OT dithiol has a half-life of 1.8h with respect to reformation of OT disulfide at 37 degrees C and pH 6.9 in the presence of the copper chelators, DTPA and neocuproine. S-Nitrosation of OT dithiol by acidified nitrite at pH 3.0 was examined by absorption spectroscopy and HPLC-UV-MS, which revealed that both singly and doubly S-nitrosated OT are formed. These results suggest novel chemical aspects to OT signaling, the biological implications of which are discussed here.





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