Keyword search (4,163 papers available)

"Woodside B" Authored Publications:

Title Authors PubMed ID
1 Effects of maternal mild hyperglycemia associated with snack intake on offspring metabolism and behavior across the lifespan Martins MG; Woodside B; Kiss ACI; 38331375
PSYCHOLOGY
2 Energetic demands of lactation produce an increase in the expression of growth hormone secretagogue receptor in the hypothalamus and ventral tegmental area of the rat despite a reduction in circulating ghrelin Wellman M; Budin R; Woodside B; Abizaid A; 35365872
PSYCHOLOGY
3 Sex differences in developmental patterns of neocortical astroglia: A mouse translatome database Rurak GM; Simard S; Freitas-Andrade M; Lacoste B; Charih F; Van Geel A; Stead J; Woodside B; Green JR; Coppola G; Salmaso N; 35108542
ENCS
4 Effects of snack intake during pregnancy and lactation on reproductive outcome in mild hyperglycemic rats Martins MG; Cruz AGD; Oliveira GP; Woodside B; Horta-Júnior JACE; Kiss ACI; 34332976
PSYCHOLOGY
5 Ghrelin receptor signalling is not required for glucocorticoid-induced obesity in female mice Silver Z; Abbott-Tate S; Hyland L; Sherratt F; Woodside B; Abizaid A; 34060474
CSBN
6 Prefrontal Cortex and Multiparity in Lactation. Opala EA, Verlezza S, Long H, Rusu D, Woodside B, Walker CD 31437474
CSBN
7 Central ghrelin receptor stimulation modulates sex motivation in male rats in a site dependent manner. Hyland L, Rosenbaum S, Edwards A, Palacios D, Graham MD, Pfaus JG, Woodside B, Abizaid A 29080670
CSBN
8 Gating of the neuroendocrine stress responses by stressor salience in early lactating female rats is independent of infralimbic cortex activation and plasticity. Hillerer KM, Woodside B, Parkinson E, Long H, Verlezza S, Walker CD 29397787
CSBN
9 Reduction and S-nitrosation of the neuropeptide oxytocin: implications for its biological function Roy JF; Chrétien MN; Woodside B; English AM; 17692543
CBAMS
10 Food restriction during lactation suppresses Kiss1 mRNA expression and kisspeptin-stimulated LH release in rats. Ladyman SR, Woodside B 24492858
CSBN
11 Physiological mechanisms, behavioral and psychological factors influencing the transfer of milk from mothers to their young. Jonas W, Woodside B 26232032
CSBN
12 Mood, Food, and Fertility: Adaptations of the Maternal Brain. Woodside B 27347899
PSYCHOLOGY

 

Title:Central ghrelin receptor stimulation modulates sex motivation in male rats in a site dependent manner.
Authors:Hyland L,  Rosenbaum S,  Edwards A,  Palacios D,  Graham MD,  Pfaus JG,  Woodside B,  Abizaid A
Link:https://www.ncbi.nlm.nih.gov/pubmed/29080670?dopt=Abstract
DOI:10.1016/j.yhbeh.2017.10.012
Publication:Hormones and behavior
Keywords:Anticipation;  Ghrelin;  Ghrelin receptor antagonist;  Ghrelin receptor knock out rats;  Intracranial drug delivery;  MPOA;  Sex motivation;  VTA; 
PMID:29080670 Category:Horm Behav Date Added:2019-06-20
Dept Affiliation: CSBN
1 Department of Neuroscience, Carleton University, Ottawa, Ontario, Canada.
2 Centre for Studies in Behavioral Neurobiology, Concordia University, Montreal, Quebec, Canada.
3 Department of Neuroscience, Carleton University, Ottawa, Ontario, Canada; Centre for Studies in Behavioral Neurobiology, Concordia University, Montreal, Quebec, Canada.
4 Department of Neuroscience, Carleton University, Ottawa, Ontario, Canada. Electronic address: alfonso_abizaid@carleton.ca.

Description:

Central ghrelin receptor stimulation modulates sex motivation in male rats in a site dependent manner.

Horm Behav. 2018 01;97:56-66

Authors: Hyland L, Rosenbaum S, Edwards A, Palacios D, Graham MD, Pfaus JG, Woodside B, Abizaid A

Abstract

Ghrelin, a hormone produced primarily by the stomach, has been associated with motivational processes that include reward-seeking behaviors. In male laboratory mice, elevation of ghrelin levels enhances some aspects of sexual motivation and behavior, whereas in other experiments with male mice, rats, and other species, ghrelin treatment or food deprivation decreases sexual motivation and/or behavior. The present tested the hypothesis that stimulation of ghrelin receptors in different brain regions have opposite effects on male sexual motivation and behavior. To do this we examined appetitive and consummatory sex behaviors of male rats with a truncated ghrelin receptor (FHH-GHSRm1/Mcwi), and that of their WT (FHH) littermates. We also examined the effects of ghrelin or the ghrelin antagonist D-Lys-GHRP6 delivered into the VTA or the MPOA on appetitive and consummatory sex behaviors in male Long Evans rats. Results demonstrate that rats with a truncated ghrelin receptor, or rats that are food deprived, show deficits in anticipatory sex. Furthermore, although ghrelin does not further stimulate sex anticipation in rats when infused into the VTA, intra-VTA infusions of D-Lys-GHRP6 into the VTA further decreases in sex anticipation in food deprived rats. In contrast, ghrelin delivery into the mPOA decreased sex anticipation compared to saline or D-Lys-GHRP6 infused rats. Overall, these data suggest that ghrelin receptor signalling is important for full expression of appetitive sex behaviors. Within the VTA, ghrelin may act to enhance sex motivation, while acting on the mPOA to decrease sex motivation and promote foraging.

PMID: 29080670 [PubMed - indexed for MEDLINE]




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