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PubMed Publications| Keyword search (4,163 papers available) |  |
"chronic low back pain" Keyword-tagged Publications:
| Title: | Relationship Between Lumbar Multifidus Morphometry and Pain/Disability in Individuals With Chronic Nonspecific Low Back Pain After Considering Demographics, Fear-Avoidance Beliefs, Insomnia, and Spinal Degenerative Changes | ||||
| Authors: | Pinto SM, Cheung JPY, Samartzis D, Karppinen J, Zheng YP, Pang MYC, Fortin M, Wong AYL | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/40376565/ | ||||
| DOI: | 10.1002/jsp2.70071 | ||||
| Publication: | JOR spine | ||||
| Keywords: | Modic changes; chronic low back pain; facet joint degeneration; fear avoidance beliefs; insomnia; lumbar multifidus; | ||||
| PMID: | 40376565 | Category: | Date Added: | 2025-05-16 | |
| Dept Affiliation: |
SOH
1 Department of Rehabilitation Sciences The Hong Kong Polytechnic University Hong Kong SAR China. 2 Department of Orthopaedics and Traumatology The University of Hong Kong Hong Kong SAR China. 3 Department of Orthopaedics Surgery Rush University Medical Center Chicago Illinois USA. 4 Medical Research Center Oulu Oulu University Hospital and University of Oulu Oulu Finland. 5 Rehabilitation Services of Wellbeing Services County of South Karelia Lappeenranta Finland. 6 Research Unit of Health Sciences and Technology University of Oulu Oulu Finland. 7 Department of Biomedical Engineering The Hong Kong Polytechnic University Hong Kong SAR China. 8 Department of Health, Kinesiology & Applied Physiology Concordia University Montreal Quebec Canada. 9 School of Health Concordia University Montreal Quebec Canada. 10 Research Institute for Smart Ageing, The Hong Kong Polytechnic University Hong Kong SAR China. |
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Description: |
Background: Although individuals with chronic low back pain (CLBP) show increased fatty infiltration in the lumbar multifidus muscle (LMM), it remains unclear whether LMM changes are related to clinical outcomes (such as pain and disability) after considering confounders (spinal phenotypes, fear-avoidance beliefs [FABs] and insomnia). This study examined: (1) differences in confounders and LMM characteristics between individuals with and without CLBP; and (2) associations between confounders, LMM parameters, and clinical outcomes in the CLBP group alone. Methods: Participants (CLBP = 70 and asymptomatic people = 67) underwent lumbar magnetic resonance imaging. Outcome measures comprised the numeric pain rating scale, the Roland-Morris Disability Questionnaire, the Fear-Avoidance Beliefs Questionnaire (FABQ), and the Insomnia Severity Index (ISI) Scale. LMM morphometry at L3-S1 (cross-sectional area, total volume, and fatty infiltration) was measured using a customized MATLAB program. Spinal phenotypes (disc degeneration, high-intensity zones, Modic changes [MCs], Schmorl's nodes, facet joint degeneration [FJD], and facet tropism [FT]) were scored. The between-group differences were analyzed using linear mixed models and chi-squared/Fisher's exact tests. Univariate and multivariate analyses evaluated associations between clinical outcomes and other outcome measures in the CLBP group. Results: The CLBP group demonstrated more severe disc degeneration and FJD at all levels, and greater FT at L5/S1 than asymptomatic participants (p < 0.05). The average LMM total volume at L3/4 and the percentage of fatty infiltration in LMM in the L3-S1 region were greater in the CLBP group than in asymptomatic counterparts (p < 0.05). The presence of MC at L4 and FJD at L4/5 and L4-S1 was significantly related to pain intensity in the CLBP group. Similarly, FABQ-Work and ISI scores were significantly related to pain intensity (explaining 37% of the variance in pain). Conclusions: The CLBP group displays more fatty infiltration in the LMM, but their LMM morphometric parameters are unrelated to pain/disability after considering spinal phenotypes, FABs, and insomnia. |
