Keyword search (4,163 papers available)

"cohort" Keyword-tagged Publications:

Title Authors PubMed ID
1 Associations of pregnancy complications with paternal cardiovascular risk: a retrospective cohort study Mussa J; Wen L; Sharafi M; Gouin JP; Rahme E; Dasgupta K; 41407531
PSYCHOLOGY
2 Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA) Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; Bélanger N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello C; Cynader M; Dang-Vu T; Das S; Dixon RA; Ducharme S; Einstein G; Evans AC; Fahnestock M; Feldman H; Ferland G; Finger E; Fisk JD; Fogarty J; Fon E; Gan-Or Z; Gauthier S; Greenwood C; Henri-Bellemare C; Herrmann N; Hogan DB; Hsiung R; Itzhak I; Jacklin K; Lanctôt K; Lim A; MacKenzie I; Masellis M; Maxwell C; McAiney C; McGilton K; McLaurin J; Mihailidis A; Mohades Z; Montero-Odasso M; Morgan D; Naglie G; Nygaard H; O' Connell M; Petersen R; Pilon R; Rajah MN; Rapoport M; Roach P; Robillard JM; Rogaeva E; Rosa-Neto P; Rylett J; Sadavoy J; St George-Hyslop P; Seitz D; Smith E; Stefanovic B; Vedel I; Walker JD; Wellington C; Whitehead V; Wittich W; 39636028
HKAP
3 Early family socioeconomic status and asthma-related outcomes in school-aged children: Results from seven birth cohort studies Yang-Huang J; McGrath JJ; Gauvin L; Nikiéma B; Spencer NJ; Awad YA; Clifford S; Markham W; Mensah F; Andersson White P; Ludvigsson J; Faresjö T; Duijts L; van Grieken A; Raat H; 38849153
PERFORM
4 Pathways of association between disordered eating in adolescence and mental health outcomes in young adulthood during the COVID-19 pandemic Loose T; Geoffroy MC; Orri M; Chadi N; Scardera S; Booij L; Breton E; Tremblay R; Boivin M; Coté S; 36482144
PSYCHOLOGY
5 Insomnia disorder increases the risk of subjective memory decline in middle-aged and older adults: a longitudinal analysis of the Canadian Longitudinal Study on Aging Zhao JL; Cross N; Yao CW; Carrier J; Postuma RB; Gosselin N; Kakinami L; Dang-Vu TT; 35877203
PERFORM
6 Household income and maternal education in early childhood and activity-limiting chronic health conditions in late childhood: findings from birth cohort studies from six countries Spencer NJ; Ludvigsson J; You Y; Francis K; Abu Awad Y; Markham W; Faresjö T; Goldhaber-Fiebert J; Andersson White P; Raat H; Mensah F; Gauvin L; McGrath JJ; 35863874
PERFORM
7 Associations of neighborhood walkability with moderate to vigorous physical activity: an application of compositional data analysis comparing compositional and non-compositional approaches Bird M; Datta GD; Chinerman D; Kakinami L; Mathieu ME; Henderson M; Barnett TA; 35585542
MATHSTATS
8 Low back pain definitions: effect on patient inclusion and clinical profiles Massé-Alarie H; Angarita-Fonseca A; Lacasse A; Pagé MG; Tétreault P; Fortin M; Léonard G; Stone LS; Roy JS; 35356510
HKAP
9 Prenatal exposure to polybrominated diphenyl ethers (PBDEs) and cognitive ability in early childhood. Azar N, Booij L, Muckle G, Arbuckle TE, Séguin JR, Asztalos E, Fraser WD, Lanphear BP, Bouchard MF 33395941
PSYCHOLOGY
10 Once online poker, always online poker? Poker modality trajectories over two years Dufour M; Morvannou A; Laverdière É; Brunelle N; Kairouz S; Nolin MA; Nadeau L; Dussault F; Berbiche D; 32467840
PSYCHOLOGY
11 The Comprehensive Assessment of Neurodegeneration and Dementia: Canadian Cohort Study. Chertkow H, Borrie M, Whitehead V, Black SE, Feldman HH, Gauthier S, Hogan DB, Masellis M, McGilton K, Rockwood K, Tierney MC, Andrew M, Hsiung GR, Camicioli R, Smith EE, Fogarty J, Lindsay J, Best S, Evans A, Das S, Mohaddes Z, Pilon R, Poirier J, Phillips NA, MacNamara E, Dixon RA, Duchesne S, MacKenzie I, Rylett RJ 31309917
PSYCHOLOGY
12 Association between insomnia disorder and cognitive function in middle-aged and older adults: a cross-sectional analysis of the Canadian Longitudinal Study on Aging Cross NE; Carrier J; Postuma RB; Gosselin N; Kakinami L; Thompson C; Chouchou F; Dang-Vu TT; 31089710
PERFORM
13 Neighbourhood disadvantage and behavioural problems during childhood and the risk of cardiovascular disease risk factors and events from a prospective cohort Kakinami L; Serbin LA; Stack DM; Karmaker SC; Ledingham JE; Schwartzman AE; 29255665
PERFORM

 

Title:Prenatal exposure to polybrominated diphenyl ethers (PBDEs) and cognitive ability in early childhood.
Authors:Azar NBooij LMuckle GArbuckle TESéguin JRAsztalos EFraser WDLanphear BPBouchard MF
Link:https://www.ncbi.nlm.nih.gov/pubmed/33395941
DOI:10.1016/j.envint.2020.106296
Publication:Environment international
Keywords:Cognitive abilityNeurodevelopmentPolybrominated diphenyl ethersPregnancy cohort
PMID:33395941 Category:Environ Int Date Added:2021-01-06
Dept Affiliation: PSYCHOLOGY
1 Department of Psychology, Concordia University, Montréal, Québec, Canada; Sainte-Justine University Hospital Research Center, Québec, Canada.
2 Department of Psychology, Concordia University, Montréal, Québec, Canada; Sainte-Justine University Hospital Research Center, Québec, Canada; Department of Psychiatry and Addictology, Université de Montréal, Montréal, Québec, Canada.
3 School of Psychology, Université Laval, Ville de Québec, Québec, Canada.
4 Environmental Health Science and Research Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada.
5 Sainte-Justine University Hospital Research Center, Québec, Canada; Department of Psychiatry and Addictology, Université de Montréal, Montréal, Québec, Canada.
6 Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada.
7 Sainte-Justine University Hospital Research Center, Québec, Canada; Centre de recherche du CHUS (CHU de Sherbrooke), Université de Sherbrooke, Sherbrooke, Québec, Canada.
8 Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.
9 Sainte-Justine University Hospital Research Center, Québec, Canada; Department of Environmental and Occupational Health, School of Public Health of the University of Montreal, Montréal, Québec, Canada. Electronic address: maryse.bouchard@umontreal.ca.

Description:

Prenatal exposure to polybrominated diphenyl ethers (PBDEs) and cognitive ability in early childhood.

Environ Int. 2021 Jan; 146:106296

Authors: Azar N, Booij L, Muckle G, Arbuckle TE, Séguin JR, Asztalos E, Fraser WD, Lanphear BP, Bouchard MF

Abstract

BACKGROUND: Prenatal exposure to polybrominated diphenyl ethers (PBDEs) has been associated with adverse neurodevelopmental outcomes in children, but evidence remains mixed regarding sex differences in this association.

OBJECTIVE: To examine the prospective association between prenatal PBDE exposure and cognitive ability in young children, as well as potential sex differences.

METHODS: The study was conducted in a multi-site Canadian pregnancy cohort recruited in 2008-11. PBDEs were measured in maternal plasma samples collected early in pregnancy. Cognitive ability was assessed using the Wechsler Preschool and Primary Scale of Intelligence (WPPSI-III) in children at age 3 years (mean = 3.4). Multiple linear regression was used to analyze the association between maternal PBDE plasma concentrations (lipid-standardized and log10-transformed) and Verbal, Performance, and Full Scale IQ scores on the whole sample and stratified by sex, adjusting for confounders.

RESULTS: The sample was composed of 592 children (291 boys and 301 girls). A tenfold increase in maternal blood PBDE concentration (sum of BDE-47, -99, -100, and -153) was associated with lower Full Scale scores in boys (-3.4 points; 95% CI: -7.0, 0.1), after adjusting for confounders. BDE-47 was the congener with the highest concentrations in maternal blood and a tenfold increase in exposure was associated with significantly lower Full Scale IQ scores in boys (-4.4 points; 95% CI: -7.9, -0.9), after adjusting for confounders. Verbal and Performance IQ scores were similarly associated with PBDE exposure. Maternal blood PBDE concentrations were not associated with IQ scores in girls.

CONCLUSIONS: Prenatal exposure to background levels of PBDEs, especially BDE-47, was associated with lower IQ scores in boys, but not in girls. Our results support that exposure to PBDEs during early development may be sex-dependent and detrimental to a child's neurodevelopmental trajectory.

PMID: 33395941 [PubMed - in process]





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