Keyword search (4,163 papers available)

"dementia" Keyword-tagged Publications:

Title Authors PubMed ID
1 Developing and Sustaining Dementia Capable Communities: An Analysis of the Current Evidence Biglieri S; Ahmed N; Main S; Tupling OL; Vijayakumar R; Boger J; Daum C; Dupuis S; Koch M; Liu L; Lopez K; Mann J; Martin M; McAiney C; Nasir HJ; Nasir N; Pearce B; Weldrick R; Vanderlinden K; Middleton L; 41432943
ENCS
2 Peripheral inflammation in a Canadian cohort of neurodegenerative conditions: Occurrence, determinants, and impact Seixas-Lima B; Rosa-Neto P; Phillips NA; Borrie M; Roncero CT; Lahiri D; Dori D; Eintracht S; Chertkow H; 41358624
PSYCHOLOGY
3 Neuropsychiatric Symptoms and Psychotropic Medication Use Following SARS-Cov-2 Infection Among Elderly Residents in Long-Term Care Facilities Cruz-Santiago D; Meng X; Canac-Marquis M; Sengupta A; Brassard JP; Pavey E; Girouard H; Vinh DC; Gouin JP; 40051588
PSYCHOLOGY
4 Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA) Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; Bélanger N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello C; Cynader M; Dang-Vu T; Das S; Dixon RA; Ducharme S; Einstein G; Evans AC; Fahnestock M; Feldman H; Ferland G; Finger E; Fisk JD; Fogarty J; Fon E; Gan-Or Z; Gauthier S; Greenwood C; Henri-Bellemare C; Herrmann N; Hogan DB; Hsiung R; Itzhak I; Jacklin K; Lanctôt K; Lim A; MacKenzie I; Masellis M; Maxwell C; McAiney C; McGilton K; McLaurin J; Mihailidis A; Mohades Z; Montero-Odasso M; Morgan D; Naglie G; Nygaard H; O' Connell M; Petersen R; Pilon R; Rajah MN; Rapoport M; Roach P; Robillard JM; Rogaeva E; Rosa-Neto P; Rylett J; Sadavoy J; St George-Hyslop P; Seitz D; Smith E; Stefanovic B; Vedel I; Walker JD; Wellington C; Whitehead V; Wittich W; 39636028
HKAP
5 The effectiveness of exercise interventions targeting sleep in older adults with cognitive impairment or Alzheimer's disease and related dementias (AD/ADRD): A systematic review and meta-analysis Arsenio Páez, Emmanuel Frimpong, Melodee Mograss, Thien Thanh Dang-Vu 38462491
HKAP
6 Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer's disease Giroud N; Pichora-Fuller MK; Mick P; Wittich W; Al-Yawer F; Rehan S; Orange JB; Phillips NA; 36911511
CRDH
7 A Community of Practice on Environmental Design for Long-Term Care Residents with Dementia Elliott J; Stolee P; Mairs K; Kothari A; Conklin J; 36799024
CONCORDIA
8 Strategies for Maintaining Friendship in Dementia Genoe MR; Fortune D; Whyte C; 35859359
CONCORDIA
9 Comment on the article "Spatially-extended nucleation-aggregation-fragmentation models for the dynamics of prion-like neurodegenerative protein-spreading in the brain and its connectome 486 (2020) 110102" Arsalan Rahimabadi 34843739
PERFORM
10 Insomnia symptom subtypes and manifestations of prodromal neurodegeneration: a population-based study in the CLSA Yao CW; Pelletier A; Fereshtehnejad SM; Cross N; Dang-Vu T; Postuma RB; 34314348
PERFORM
11 Gait variability across neurodegenerative and cognitive disorders: Results from the Canadian Consortium of Neurodegeneration in Aging (CCNA) and the Gait and Brain Study. Pieruccini-Faria F, Black SE, Masellis M, Smith EE, Almeida QJ, Li KZH, Bherer L, Camicioli R, Montero-Odasso M 33590967
PSYCHOLOGY
12 PM2.5 and hospital admissions among Medicare enrollees with chronic debilitating brain disorders. Yitshak-Sade M, Nethery R, Schwartz JD, Mealli F, Dominici F, Di Q, Abu Awad Y, Ifergane G, Zanobetti A 33065503
PSYCHOLOGY
13 CCCDTD5 recommendations on early non cognitive markers of dementia: A Canadian consensus Montero-Odasso M; Pieruccini-Faria F; Ismail Z; Li K; Lim A; Phillips N; Kamkar N; Sarquis-Adamson Y; Speechley M; Theou O; Verghese J; Wallace L; Camicioli R; 33094146
CRDH
14 Behavioral and Psychological Symptoms that Predict Cognitive Decline or Impairment in Cognitively Normal Middle-Aged or Older Adults: a Meta-Analysis. Hudon C, Escudier F, De Roy J, Croteau J, Cross N, Dang-Vu TT, Zomahoun HTV, Grenier S, Gagnon JF, Parent A, Bruneau MA, Belleville S, Consortium for the Early Identification of Alzheimer’s Disease Quebec 32394109
HKAP
15 The Comprehensive Assessment of Neurodegeneration and Dementia: Canadian Cohort Study. Chertkow H, Borrie M, Whitehead V, Black SE, Feldman HH, Gauthier S, Hogan DB, Masellis M, McGilton K, Rockwood K, Tierney MC, Andrew M, Hsiung GR, Camicioli R, Smith EE, Fogarty J, Lindsay J, Best S, Evans A, Das S, Mohaddes Z, Pilon R, Poirier J, Phillips NA, MacNamara E, Dixon RA, Duchesne S, MacKenzie I, Rylett RJ 31309917
PSYCHOLOGY
16 SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment. Montero-Odasso M, Almeida QJ, Burhan AM, Camicioli R, Doyon J, Fraser S, Li K, Liu-Ambrose T, Middleton L, Muir-Hunter S, McIlroy W, Morais JA, Pieruccini-Faria F, Shoemaker K, Speechley M, Vasudev A, Zou GY, Berryman N, Lussier M, Vanderhaeghe L, Bherer L 29661156
PERFORM

 

Title:CCCDTD5 recommendations on early non cognitive markers of dementia: A Canadian consensus
Authors:Montero-Odasso MPieruccini-Faria FIsmail ZLi KLim APhillips NKamkar NSarquis-Adamson YSpeechley MTheou OVerghese JWallace LCamicioli R
Link:https://pubmed.ncbi.nlm.nih.gov/33094146/
DOI:10.1002/trc2.12068
Publication:Alzheimer s & dementia (New York, N. Y.)
Keywords:behaviorbiomarkercognitive impairmentdementiafrailtygaithearingolfactionparkinsonismpredictionrisksleepvision
PMID:33094146 Category:Alzheimers Dement (N Y) Date Added:2020-10-24
Dept Affiliation: CRDH
1 Gait and Brain Laboratory Parkwood Institute Lawson Health Research Institute London Ontario Canada.
2 Division of Geriatric Medicine Department of Medicine Schulich School of Medicine and Dentistry London Ontario Canada.
3 Department of Epidemiology and Biostatistics University of Western Ontario London Ontario Canada.
4 Departments of Psychiatry Clinical Neurosciences and Community Health Sciences Hotchkiss Brain Institute and O'Brien Institute for Public Health University of Calgary Calgary Alberta Canada.
5 Centre for Research in Human Development Concordia University Montreal Quebec Canada.
6 Department of Psychology Concordia University Quebec Canada.
7 Division of Neurology Department of Medicine Sunnybrook Health Sciences Centre Toronto Ontario Canada.
8 School of Physiotherapy Dalhousie University Halifax Nova Scotia Canada.
9 Department of Medicine Dalhousie University Halifax Nova Scotia Canada.
10 Department of Neurology Albert Einstein College of Medicine Bronx New York USA.
11 Division of Neurology Department of Medicine University of Alberta Edmonton Alberta Canada.

Description:

Introduction: Cognitive impairment is the hallmark of Alzheimer's disease (AD) and related dementias. However, motor decline has been recently described as a prodromal state that can help to detect at-risk individuals. Similarly, sensory changes, sleep and behavior disturbances, and frailty have been associated with higher risk of developing dementia. These clinical findings, together with the recognition that AD pathology precedes the diagnosis by many years, raises the possibility that non-cognitive changes may be early and non-invasive markers for AD or, even more provocatively, that treating non-cognitive aspects may help to prevent or treat AD and related dementias.

Methods: A subcommittee of the Canadian Consensus Conference on Diagnosis and Treatment of Dementia reviewed areas of emerging evidence for non-cognitive markers of dementia. We examined the literature for five non-cognitive domains associated with future dementia: motor, sensory (hearing, vision, olfaction), neuro-behavioral, frailty, and sleep. The Grading of Recommendations Assessment, Development, and Evaluation system was used to assign the strength of the evidence and quality of the recommendations. We provide recommendations to primary care clinics and to specialized memory clinics, answering the following main questions: (1) What are the non-cognitive and functional changes associated with risk of developing dementia? and (2) What is the evidence that sensory, motor, behavioral, sleep, and frailty markers can serve as potential predictors of dementia?

Results: Evidence supported that gait speed, dual-task gait speed, grip strength, frailty, neuropsychiatric symptoms, sleep measures, and hearing loss are predictors of dementia. There was insufficient evidence for recommending assessing olfactory and vision impairments as a predictor of dementia.

Conclusions: Non-cognitive markers can assist in identifying people at risk for cognitive decline or dementia. These non-cognitive markers may represent prodromal symptoms and several of them are potentially amenable to treatment that might delay the onset of cognitive decline.





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