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PubMed Publications| Keyword search (4,163 papers available) |  |
"dementia" Keyword-tagged Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Developing and Sustaining Dementia Capable Communities: An Analysis of the Current Evidence | Biglieri S; Ahmed N; Main S; Tupling OL; Vijayakumar R; Boger J; Daum C; Dupuis S; Koch M; Liu L; Lopez K; Mann J; Martin M; McAiney C; Nasir HJ; Nasir N; Pearce B; Weldrick R; Vanderlinden K; Middleton L; | 41432943 ENCS |
| 2 | Peripheral inflammation in a Canadian cohort of neurodegenerative conditions: Occurrence, determinants, and impact | Seixas-Lima B; Rosa-Neto P; Phillips NA; Borrie M; Roncero CT; Lahiri D; Dori D; Eintracht S; Chertkow H; | 41358624 PSYCHOLOGY |
| 3 | Neuropsychiatric Symptoms and Psychotropic Medication Use Following SARS-Cov-2 Infection Among Elderly Residents in Long-Term Care Facilities | Cruz-Santiago D; Meng X; Canac-Marquis M; Sengupta A; Brassard JP; Pavey E; Girouard H; Vinh DC; Gouin JP; | 40051588 PSYCHOLOGY |
| 4 | Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA) | Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; Bélanger N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello C; Cynader M; Dang-Vu T; Das S; Dixon RA; Ducharme S; Einstein G; Evans AC; Fahnestock M; Feldman H; Ferland G; Finger E; Fisk JD; Fogarty J; Fon E; Gan-Or Z; Gauthier S; Greenwood C; Henri-Bellemare C; Herrmann N; Hogan DB; Hsiung R; Itzhak I; Jacklin K; Lanctôt K; Lim A; MacKenzie I; Masellis M; Maxwell C; McAiney C; McGilton K; McLaurin J; Mihailidis A; Mohades Z; Montero-Odasso M; Morgan D; Naglie G; Nygaard H; O' Connell M; Petersen R; Pilon R; Rajah MN; Rapoport M; Roach P; Robillard JM; Rogaeva E; Rosa-Neto P; Rylett J; Sadavoy J; St George-Hyslop P; Seitz D; Smith E; Stefanovic B; Vedel I; Walker JD; Wellington C; Whitehead V; Wittich W; | 39636028 HKAP |
| 5 | The effectiveness of exercise interventions targeting sleep in older adults with cognitive impairment or Alzheimer's disease and related dementias (AD/ADRD): A systematic review and meta-analysis | Arsenio Páez, Emmanuel Frimpong, Melodee Mograss, Thien Thanh Dang-Vu | 38462491 HKAP |
| 6 | Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer's disease | Giroud N; Pichora-Fuller MK; Mick P; Wittich W; Al-Yawer F; Rehan S; Orange JB; Phillips NA; | 36911511 CRDH |
| 7 | A Community of Practice on Environmental Design for Long-Term Care Residents with Dementia | Elliott J; Stolee P; Mairs K; Kothari A; Conklin J; | 36799024 CONCORDIA |
| 8 | Strategies for Maintaining Friendship in Dementia | Genoe MR; Fortune D; Whyte C; | 35859359 CONCORDIA |
| 9 | Comment on the article "Spatially-extended nucleation-aggregation-fragmentation models for the dynamics of prion-like neurodegenerative protein-spreading in the brain and its connectome 486 (2020) 110102" | Arsalan Rahimabadi | 34843739 PERFORM |
| 10 | Insomnia symptom subtypes and manifestations of prodromal neurodegeneration: a population-based study in the CLSA | Yao CW; Pelletier A; Fereshtehnejad SM; Cross N; Dang-Vu T; Postuma RB; | 34314348 PERFORM |
| 11 | Gait variability across neurodegenerative and cognitive disorders: Results from the Canadian Consortium of Neurodegeneration in Aging (CCNA) and the Gait and Brain Study. | Pieruccini-Faria F, Black SE, Masellis M, Smith EE, Almeida QJ, Li KZH, Bherer L, Camicioli R, Montero-Odasso M | 33590967 PSYCHOLOGY |
| 12 | PM2.5 and hospital admissions among Medicare enrollees with chronic debilitating brain disorders. | Yitshak-Sade M, Nethery R, Schwartz JD, Mealli F, Dominici F, Di Q, Abu Awad Y, Ifergane G, Zanobetti A | 33065503 PSYCHOLOGY |
| 13 | CCCDTD5 recommendations on early non cognitive markers of dementia: A Canadian consensus | Montero-Odasso M; Pieruccini-Faria F; Ismail Z; Li K; Lim A; Phillips N; Kamkar N; Sarquis-Adamson Y; Speechley M; Theou O; Verghese J; Wallace L; Camicioli R; | 33094146 CRDH |
| 14 | Behavioral and Psychological Symptoms that Predict Cognitive Decline or Impairment in Cognitively Normal Middle-Aged or Older Adults: a Meta-Analysis. | Hudon C, Escudier F, De Roy J, Croteau J, Cross N, Dang-Vu TT, Zomahoun HTV, Grenier S, Gagnon JF, Parent A, Bruneau MA, Belleville S, Consortium for the Early Identification of Alzheimer’s Disease – Quebec | 32394109 HKAP |
| 15 | The Comprehensive Assessment of Neurodegeneration and Dementia: Canadian Cohort Study. | Chertkow H, Borrie M, Whitehead V, Black SE, Feldman HH, Gauthier S, Hogan DB, Masellis M, McGilton K, Rockwood K, Tierney MC, Andrew M, Hsiung GR, Camicioli R, Smith EE, Fogarty J, Lindsay J, Best S, Evans A, Das S, Mohaddes Z, Pilon R, Poirier J, Phillips NA, MacNamara E, Dixon RA, Duchesne S, MacKenzie I, Rylett RJ | 31309917 PSYCHOLOGY |
| 16 | SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment. | Montero-Odasso M, Almeida QJ, Burhan AM, Camicioli R, Doyon J, Fraser S, Li K, Liu-Ambrose T, Middleton L, Muir-Hunter S, McIlroy W, Morais JA, Pieruccini-Faria F, Shoemaker K, Speechley M, Vasudev A, Zou GY, Berryman N, Lussier M, Vanderhaeghe L, Bherer L | 29661156 PERFORM |
| Title: | Insomnia symptom subtypes and manifestations of prodromal neurodegeneration: a population-based study in the CLSA | ||||
| Authors: | Yao CW, Pelletier A, Fereshtehnejad SM, Cross N, Dang-Vu T, Postuma RB | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/34314348/ | ||||
| DOI: | 10.5664/jcsm.9562 | ||||
| Publication: | Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine | ||||
| Keywords: | dementia; insomnia; movement disorder; neurodegeneration; | ||||
| PMID: | 34314348 | Category: | Date Added: | 2021-07-27 | |
| Dept Affiliation: |
PERFORM
1 Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada. 2 Research Institute of the McGill University Health Centre, Montreal, QC, Canada. 3 Research center of the Hôpital du Sacré-Coeur de Montréal, Montreal, QC, Canada. 4 Division of Neurology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada. 5 Institut Universitaire de Gériatrie de Montréal and CRIUGM, CIUSSS du Centre-Sud-de-l'Île-de-Montréal, Montreal, QC, Canada. 6 PERFORM Centre, Center for Studies in Behavioral Neurobiology, Department of Health, Kinesiology and Applied Physiology, Concordia University, Montreal, QC, Canada. 7 Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada. |
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Description: |
Study objectives: To identify the association between insomnia symptoms and signs of prodromal neurodegeneration, including an analysis of potential differences between sleep-onset and sleep-maintenance insomnia. Methods: We included those aged 45-85 years, living in one of 10 Canadian provinces in between 2012-2015 (at the baseline), recruited via three population-based sampling methods. Insomnia symptoms were assessed using questions adapted/modified from the Pittsburgh Sleep Quality Index. A panel of potential prodromal neurodegenerative markers including self-reported symptoms and objective gait motor, cognitive, and autonomic variables were assessed cross-sectionally. We compared those who endorsed insomnia symptoms =3 times per week to controls, adjusting for age, sex and education via logistic regression. Results: Overall, 2,051/30,097 people screened positive for sleep-onset insomnia alone and 4,333 for sleep-maintenance insomnia alone, while 2,371 endorsed both subtypes. On objective gait tests, participants with sleep-onset insomnia, but not sleep-maintenance insomnia, had worse balance (OR = 1.33[1.16,1.52]) and slower gait speed (OR = 1.52[1.34,1.73]). Although participants with any insomnia subtype endorsed more motor symptoms, these were more severe in those with sleep-onset insomnia (OR onset vs. maintenance = 1.13 [1.07,1.18]). On objective cognitive tests, those with sleep-maintenance insomnia scored normally. However, participants with sleep-onset insomnia performed worse on tests of verbal fluency (OR = 1.24[1.06,1.43]) immediate memory (OR = 1.23[1.08,1.41]), and prospective memory task (OR = 1.29[1.11,1.50]). The sleep-onset insomnia group also had lower heart rate variability (OR = 1.23[1.07,1.43]). Secondary analyses found generally similar results in young vs. older age of insomnia development. Conclusions: Compared to maintenance insomnia, those with sleep-onset insomnia have more motor, cognitive and autonomic signs/symptoms. When evaluating neurodegenerative risk, differentiating insomnia subtypes may increase precision. |
