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Scalable Synthesis of High-Quality Graphene Quantum Dots by Reductive Intercalation/Exfoliation of Coal

Author(s): Bepete G; Ratnayake G; Sanchez DE; Yu Z; Dimitrov E; Fest Carreno A; Oliveira MCD; Viana BC; Santos FEP; Terrones M;

Coal, historically a low-cost and abundant energy resource, is emerging as a promising carbon-rich precursor for advanced nanomaterials. In this work, we introduce a reductive intercalation strategy to synthesize reduced (electron-rich) graphene quantum dots (GQDs) directly from anthracite coal. ...

Article GUID: 41081673


Cerebral small vessel disease lesion segmentation methods: A systematic review

Author(s): Phelps J; Singh M; McCreary CR; Dallaire-Théroux C; Stein RG; Potvin-Jutras Z; Guan DX; Wu JD; Metz A; Smith EE;

Cerebral small vessel disease (CSVD) can manifest as brain lesions visible on magnetic resonance imaging, including white matter hyperintensities (WMH), cerebral microbleeds (CMB), perivascular spaces (PVS), lacunes, and recent small subcortical infarcts (RSSI). Detection and segmentation of thes ...

Article GUID: 41080650


Preprocessing narrative texts in electronic medical records to identify hospital adverse events: A scoping review

Author(s): Jafarpour H; Wu G; Cheligeer CK; Yan J; Xu Y; Southern DA; Eastwood CA; Zeng Y; Quan H;

Background: Narrative electronic medical records (EMR), which include textual notes created by clinicians within healthcare environments, represent a significant resource for documenting various facets of patient care. This form of text exhibits distinctive characteristics, such as the occurrence of grammatically incorrect sentences, abbreviations, freque ...

Article GUID: 41072367


Toward a Sustainable Future: A Holistic Environmental, Social, and Economic Assessment of Industrial Recycling for All-Solid-State Batteries with Oxide-Based Electrolytes

Author(s): Wang Z; Tian X; Zhao S; Zhang P; An C;

The increasing demand for lithium-ion batteries has raised concerns about resource scarcity, battery accident risks, and end-of-life battery management. All-solid-state batteries (ASSBs) are emerging as a promising alternative due to their higher energy density and thermal stability. However, the large-scale production of ASSBs necessitates the developmen ...

Article GUID: 41073076


Automated abdominal aortic calcification and trabecular bone score independently predict incident fracture during routine osteoporosis screening

Author(s): Gebre AK; Sim M; Gilani SZ; Saleem A; Smith C; Hans D; Reid S; Monchka BA; Kimelman D; Jozani MJ; Schousboe JT; Lewis JR; Leslie WD;

Abdominal aortic calcification (AAC), a marker of subclinical cardiovascular disease, has previously shown to be associated with low bone mineral density (BMD) and fracture. However, it remains unclear whether AAC is associated with trabecular bone score (TBS), a gray-level textural measure, or w ...

Article GUID: 41071096


The Need for Health Systems to Engage With and Support Youth who are Caregivers-A Lived Experience Perspective From Young Carers

Author(s): Grant A; Goberdhan N; Mar K; Ramkishun A; Rahman S; Redublo T; Caven I; Okrainec K;

Caregivers under the age of 25, or young carers, lack significant recognition and support across sectors of education, employment, and healthcare. As young carer advisors on a prior research project exploring Canadian healthcare providers' awareness of young carers in their clinical practice, we were a part of an experience-based co-design process to ...

Article GUID: 41064416


Body maps of the sensation of musical groove

Author(s): Witek MAG; Matthews TE; Bechtold TA; Penhune V;

Rhythmic music often leads to an urge to move the body in time with the music. This urge to move can be a pleasurable experience. In psychology, we define the pleasurable wanting to move to music as groove. Here, we investigate where in the body these two groove components-movement and pleasure-are felt and whether the embodied sensations depend on the mu ...

Article GUID: 41064243


Predicting the way forward for the Global Biodiversity Framework

Author(s): Zurell D; Bocedi G; Velazco SJE; Gonzalez A; Purvis A; Wintle B; Merow C; Lundquist C; Guillera-Arroita G; Settele J; Serra-Diaz JM; Cabral JS; Travis JMJ; Schifferle K; Buckley L; Briscoe NJ; Isaac NJB; Peres-Neto PR; Keuth R; Gascoigne SJL; Ferrier S; Urban MC;

Article GUID: 41060752


Sequential antibiotic exposure restores antibiotic susceptibility

Author(s): Chowdhury FR; Findlay BL;

Background: The prevalence of antibiotic resistance continues to rise, rendering many valuable antimicrobial drugs ineffective. Pairwise cyclic antibiotic therapy, where treatment is rapidly switched between two antibiotics, has been demonstrated in vitro to limit the evolution of antibiotic resistance. However, what happens when resistance inevitably evo ...

Article GUID: 41060280


Enhancing X-ray Activated Photodynamic Therapy with Supported Lipid Bilayer-Coated Radioluminescent Nanoparticles

Author(s): Bondon N; Mandl GA; Mena-Giraldo P; Ferron Z; Sadeghipour N; DeWolf C; Capobianco JA;

We report the synthesis of supported lipid bilayer (SLB)-coated radioluminescent nanoparticles (RLNPs) possessing a lanthanide-based core for low-dose X-ray activated photodynamic therapy (XPDT). Methylene blue (MB) photosensitizer molecules, incorporated within the SLB, are excited by energy transfer from europium, leading to an enhanced generation of re ...

Article GUID: 41059546


Finding a Link Between the TRPV4 Ion Channel and Angiogenesis: A Potential Therapeutic Target for Vascular Remodeling

Author(s): Malka G; Salucci V; Bergdahl A;

Angiogenesis, the formation of new blood vessels, is crucial in ischemic heart disease to improve blood supply to the heart. Meanwhile, in cancer, inhibiting angiogenesis can limit tumor growth by reducing oxygen and nutrients. Calcium ions, key in cellular functions like proliferation and migration, play an important role in this process. TRPV4, a calciu ...

Article GUID: 41056565


Identification of five sleep-biopsychosocial profiles with specific neural signatures linking sleep variability with health, cognition, and lifestyle factors

Author(s): Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Yeo BTT;

Sleep is essential for optimal functioning and health. Interconnected to multiple biological, psychological, and socio-environmental factors (i.e., biopsychosocial factors), the multidimensional nature of sleep is rarely capitalized on in research. Here, we deployed a data-driven approach to iden ...

Article GUID: 41056215


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