Keyword search (3,254 papers available)


Multi-tissue patterning drives anterior morphogenesis of the C. elegans embryo.

Author(s): Grimbert S, Mastronardi K, Richard V, Christensen R, Law C, Zardoui K, Fay D, Piekny A

Complex structures derived from multiple tissue types are challenging to study in vivo, and our knowledge of how cells from different tissues are coordinated is limited. Model organisms have proven invaluable for improving our understanding of how chemical ...

Article GUID: 33309948

The phenotype associated with variants in TANGO2 may be explained by a dual role of the protein in ER-to-Golgi transport and at the mitochondria.

Author(s): Milev MP, Saint-Dic D, Zardoui K, Klopstock T, Law C, Distelmaier F, Sacher M

TANGO2 variants result in a complex disease phenotype consisting of recurrent crisis-induced rhabdomyolysis, encephalopathy, seizures, lactic acidosis, hypoglycemia, and cardiac arrhythmias. Although first described in a fruit fly model as a protein necessa...

Article GUID: 32909282

Photosystem Biogenesis Is Localized to the Translation Zone in the Chloroplast of Chlamydomonas.

Author(s): Sun Y, Valente-Paterno MI, Bakhtiari S, Law C, Zhan Y, Zerges W

Photosystem Biogenesis Is Localized to the Translation Zone in the Chloroplast of Chlamydomonas.

Plant Cell. 2019 Oct 07;:

Authors: Sun Y, Valente-Paterno MI, Bakhtiari S, Law C, Zhan Y, Zerges W

Abstract
Intracellular pro...

Article GUID: 31591163

Active Ran regulates anillin function during cytokinesis.

Author(s): Beaudet D, Akhshi T, Phillipp J, Law C, Piekny A

Mol Biol Cell. 2017 Nov 15;28(24):3517-3531 Authors: Beaudet D, Akhshi T, Phillipp J, Law C, Piekny A

Article GUID: 28931593


Title:Photosystem Biogenesis Is Localized to the Translation Zone in the Chloroplast of Chlamydomonas.
Authors:Sun YValente-Paterno MIBakhtiari SLaw CZhan YZerges W
Link:www.ncbi.nlm.nih.gov/pubmed/31591163?dopt=Abstract
Category:Plant Cell
PMID:31591163
Dept Affiliation: GENOMICS
1 Department of Biology and Centre for Structural and Functional Genomics, Concordia University, Montreal, Quebec H4B 1R6, Canada.
2 Centre for Microscopy and Cellular Imaging, Concordia University, Montreal, Quebec H4B 1R6, Canada.
3 Department of Biology and Centre for Structural and Functional Genomics, Concordia University, Montreal, Quebec H4B 1R6, Canada william.zerges@concordia.ca.

Description:

Photosystem Biogenesis Is Localized to the Translation Zone in the Chloroplast of Chlamydomonas.



Plant Cell. 2019 Oct 07;:



Authors: Sun Y, Valente-Paterno MI, Bakhtiari S, Law C, Zhan Y, Zerges W



Abstract

Intracellular processes can be localized for efficiency or regulation. For example, localized mRNA translation by chloroplastic ribosomes occurs in the biogenesis of photosystem II, one of the two photosystems of the photosynthetic electron transport chain in the chloroplasts of plants and algae. The biogenesis of both photosystems, I and II, requires the synthesis and assembly of their constituent polypeptide subunits, pigments, and cofactors. Although these biosynthetic pathways are well characterized, less is known about when and where they occur in developing chloroplasts. We used fluorescence microscopy in the unicellular alga Chlamydomonas reinhardtii to reveal spatiotemporal organization in photosystem biogenesis. We focused on translation by chloroplastic ribosomes and chlorophyll biosynthesis in two developmental contexts of active photosystem biogenesis: 1) growth of the mature chloroplast and 2) greening of a non-photosynthetic chloroplast. The results reveal that a translation zone is the primary location of the biogenesis of photosystems I and II. This discretely localized region within the chloroplast contrasts with the distributions of photosystems throughout this organelle and, therefore, is likely a hub where anabolic pathways converge for photosystem biogenesis.



PMID: 31591163 [PubMed - as supplied by publisher]