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Effects of bilateral anterior agranular insula lesions on food anticipatory activity in rats.

Author(s): Gavrila AM, Hood S, Robinson B, Amir S

PLoS One. 2017;12(6):e0179370 Authors: Gavrila AM, Hood S, Robinson B, Amir S

Article GUID: 28594962
Comprehensive mapping of regional expression of the clock protein PERIOD2 in rat forebrain across the 24-h day.

Author(s): Harbour VL, Weigl Y, Robinson B, Amir S

PLoS One. 2013;8(10):e76391 Authors: Harbour VL, Weigl Y, Robinson B, Amir S

Article GUID: 24124556
Phase differences in expression of circadian clock genes in the central nucleus of the amygdala, dentate gyrus, and suprachiasmatic nucleus in the rat.

Author(s): Harbour VL, Weigl Y, Robinson B, Amir S

PLoS One. 2014;9(7):e103309 Authors: Harbour VL, Weigl Y, Robinson B, Amir S

Article GUID: 25068868
Stress-induced changes in the expression of the clock protein PERIOD1 in the rat limbic forebrain and hypothalamus: role of stress type, time of day, and predictability.

Author(s): Al-Safadi S, Al-Safadi A, Branchaud M, Rutherford S, Dayanandan A, Robinson B, Amir S

PLoS One. 2014;9(10):e111166 Authors: Al-Safadi S, Al-Safadi A, Branchaud M, Rutherford S, Dayanandan A, Robinson B, Amir S

Article GUID: 25338089
Title:Phase differences in expression of circadian clock genes in the central nucleus of the amygdala, dentate gyrus, and suprachiasmatic nucleus in the rat.
Authors:Harbour VL,  Weigl Y,  Robinson B,  Amir S
Link:https://www.ncbi.nlm.nih.gov/pubmed/25068868?dopt=Abstract
Category:PLoS One
PMID:25068868
Dept Affiliation: PSYCHOLOGY
1 Center for Studies in Behavioral Neurobiology/Groupe de Recherche en Neurobiologie Comportementale, Department of Psychology, Concordia University, Montreal, QC, Canada.

Description:

Phase differences in expression of circadian clock genes in the central nucleus of the amygdala, dentate gyrus, and suprachiasmatic nucleus in the rat.

PLoS One. 2014;9(7):e103309

Authors: Harbour VL, Weigl Y, Robinson B, Amir S

Abstract

We performed a high temporal resolution analysis of the transcript level of two core clock genes, Period2 (Per2) and Bmal1, and a clock output gene, Dbp, in the suprachiasmatic nucleus (SCN), the master circadian clock, and in two forebrain regions, the lateral part of the central nucleus of the amygdala (CEAl), and dentate gyrus (DG), in rats. These regions, as we have shown previously, exhibit opposite rhythms in expression of the core clock protein, PERIOD2 (PER2). We found that the expression of Per2, Bmal1 and Dbp follow a diurnal rhythm in all three regions but the phase and amplitude of the rhythms of each gene vary across regions, revealing important regional differences in temporal dynamics underlying local daily rhythm generation in the mammalian forebrain. These findings underscore the complex temporal organization of subordinate circadian oscillators in the forebrain and raise interesting questions about the functional connection of these oscillators with the master SCN clock.

PMID: 25068868 [PubMed - indexed for MEDLINE]