Keyword search (3,681 papers available)


Four-week prehabilitation program is sufficient to modify exercise behaviors and improve preoperative functional walking capacity in patients with colorectal cancer.

Author(s): Chen BP, Awasthi R, Sweet SN, Minnella EM, Bergdahl A, Santa Mina D, Carli F, Scheede-Bergdahl C

Support Care Cancer. 2017 01;25(1):33-40 Authors: Chen BP, Awasthi R, Sweet SN, Minnella EM, Bergdahl A, Santa Mina D, Carli F, Scheede-Bergdahl C

Article GUID: 27539131
Adaptation of mitochondrial expression and ATP production in dedifferentiating vascular smooth muscle cells.

Author(s): Scheede-Bergdahl C, Bergdahl A

Can J Physiol Pharmacol. 2017 Dec;95(12):1473-1479 Authors: Scheede-Bergdahl C, Bergdahl A

Article GUID: 28846852
Evaluation of supervised multimodal prehabilitation programme in cancer patients undergoing colorectal resection: a randomized control trial.

Author(s): Bousquet-Dion G, Awasthi R, Loiselle SÈ, Minnella EM, Agnihotram RV, Bergdahl A, Carli F, Scheede-Bergdahl C

Acta Oncol. 2018 Jun;57(6):849-859 Authors: Bousquet-Dion G, Awasthi R, Loiselle SÈ, Minnella EM, Agnihotram RV, Bergdahl A, Carli F, Scheede-Bergdahl C

Article GUID: 29327644
Maximizing patient adherence to prehabilitation: what do the patients say?

Author(s): Ferreira V, Agnihotram RV, Bergdahl A, van Rooijen SJ, Awasthi R, Carli F, Scheede-Bergdahl C

Support Care Cancer. 2018 Aug;26(8):2717-2723 Authors: Ferreira V, Agnihotram RV, Bergdahl A, van Rooijen SJ, Awasthi R, Carli F, Scheede-Bergdahl C

Article GUID: 29478189
Cardiac mitochondrial respiration following a low-carbohydrate, high-fat diet in apolipoprotein E-deficient mice.

Author(s): Rocha C, Koury OH, Scheede-Bergdahl C, Bergdahl A

J Physiol Biochem. 2019 Feb;75(1):65-72 Authors: Rocha C, Koury OH, Scheede-Bergdahl C, Bergdahl A

Article GUID: 30362048
Title:Cardiac mitochondrial respiration following a low-carbohydrate, high-fat diet in apolipoprotein E-deficient mice.
Authors:Rocha C,  Koury OH,  Scheede-Bergdahl C,  Bergdahl A
Link:https://www.ncbi.nlm.nih.gov/pubmed/30362048?dopt=Abstract
Category:J Physiol Biochem
PMID:30362048
Dept Affiliation: HKAP
1 Department of Health, Kinesiology & Applied Physiology, Concordia University, 7141 Sherbrooke West, Montreal, QC, H4B 1R6, Canada.
2 Department of Kinesiology and Physical Education, McGill Research Centre for Physical Activity & Health, McGill University, 475 Pine Avenue West, Montreal, H2W 1S4, QC, Canada.
3 Department of Health, Kinesiology & Applied Physiology, Concordia University, 7141 Sherbrooke West, Montreal, QC, H4B 1R6, Canada. andreas.bergdahl@concordia.ca.

Description:

Cardiac mitochondrial respiration following a low-carbohydrate, high-fat diet in apolipoprotein E-deficient mice.

J Physiol Biochem. 2019 Feb;75(1):65-72

Authors: Rocha C, Koury OH, Scheede-Bergdahl C, Bergdahl A

Abstract

Low-carbohydrate diets are considered to be an effective approach to weight loss and have, subsequently, grown in popularity. Despite the apparent health benefits that these diets may provide for insulin resistance, hypertension, and dyslipidemia, their implications on cardiomyocyte oxidative capacity have yet to be investigated. To evaluate the adaptations induced by a 6-week low-carbohydrate, high-fat (LCHF) diet on mitochondrial respiration, two groups of male mice were investigated: Apolipoprotein E-deficient mice on a LCHF diet (L-DIET) and apolipoprotein E-deficient mice on a regular rodent diet (CON). Heart tissue was extracted and used for high-resolution respirometry (HRR), while immunoblotting was performed to quantify mitochondrial density and complexes. The results demonstrate increased expression of all five mitochondrial subunits in the L-DIET group compared to control condition. Furthermore, HRR revealed increased efficiency of substrate consumption, implying augmented oxidative capacity in the L-DIET group. These findings further support the notion that cardiomyocytes prefer lipids as a primary fuel source, by demonstrating that the shift in metabolism caused by a LCHF diet facilitates such an environment. This provides important information regarding the effects of a LCHF on cardiomyocytes, especially when considering free radical production and heart dysfunction.

PMID: 30362048 [PubMed - indexed for MEDLINE]